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195 Possible Causes for Acetylases,, Arylamine

Did you mean: Acetylases, acrylamide

  • Malignant Neoplasm

    Ikura T, Ogryzko VV, Grigoriev M, Groisman R, Wang J, et al. (2000) Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 102: 463–473.[doi.org] […] mutagenesis or tumorigenesis induced by vinyl carbamate and N-nitrosodimethylamine; aflatoxin B1-induced and N-nitrosodiethylamine-induced liver preneoplastic foci in rats; arylamine[dx.doi.org]

  • Isoniazid

    .: The frequency of isoniazid acetylase enzyme deficiency among Egyptians. American Journal of Physical Anthropology 31: 97–102 (1969).[link.springer.com] Details Arylamine N-acetyltransferase 1 NAT1*14B Not Available G A ADR Inferred Increased risk of toxic reactions.[drugbank.ca] Table 1 Pharmacokinetic assessment at 1 month after initiation of antituberculosis treatment, according to arylamine N -acetyltransferase 2 ( NAT2 ) genotype.[dx.doi.org]

  • Dimethyl Sulfoxide

    IC50 : HII4E cells : IC 50 199 µg.mL-1 (mouse) Ki Data : Choline acetylase: K i 25 mM (rat) pK Values : pK a : -4.54 (Predicted) For Research Use Only.[scbt.com] Notably, the arylamine reactants also acted as indispensable catalysts to promote enamine formation. X. Geng, X. Wu, P. Zhao, J. Zhang, Y.-D. Wu, A.-X. Wu, Org.[organic-chemistry.org] IC50 : HII4E cells : IC 50 199 µg/ml (mouse) Ki Data : Choline acetylase: K i 25000000 nM (Rattus norvegicus) For Research Use Only.[scbt.com]

  • Shigella Flexneri

    PubMed Google Scholar Clark CA, Beltrame J, Manning PA: The oac gene encoding a lipopolysaccharide O-antigen acetylase maps adjacent to the integrase-encoding gene on the[bmcmicrobiol.biomedcentral.com] Structure of arylamine N -acetyltransferase reveals a catalytic triad . Nature Struct. Biol. 7 , 560–564 (2000) 19. Kitadokoro, K. et al.[doi.org] Clark CA, Beltrame J, Manning PA (1991) The oac gene encoding a lipopolysaccharide O-antigen acetylase maps adjacent to the integrase-encoding gene on the genome of Shigella[journals.plos.org]

  • Sulfonamide

    […] that lack the arylamine group, and may therefore safely take non-arylamine sulfonamides.[en.wikipedia.org] ., an N-containing ring attached to the N1 nitrogen of the sulfonamide group and an arylamine group at the N4 position), and only two agents (amprenavir and fosamprenavir)[ncbi.nlm.nih.gov] The sulfonamides were all classified according to the presence or absence of the N1 substituent and the N4 arylamine.[ajhp.org]

    Missing: Acetylases
  • Sulfasalazine

    Arylamine N-acetyltransferase 1 NAT1*14A Not Available G A T A C A ADR Inferred Increased risk of Sulfapyridine dose related adverse effects, including skin rash.[drugbank.ca] METHODS: Arylamine N-acetyltransferase 1 (NAT1) and arylamine N-acetyltransferase 2 (NAT2) genotypes were determined in 266 AS patients who received SSZ treatment and 280[ncbi.nlm.nih.gov] Details Arylamine N-acetyltransferase 1 NAT1*14B Not Available G A ADR Inferred Increased risk of Sulfapyridine dose related adverse effects, including skin rash.[drugbank.ca]

    Missing: Acetylases
  • Carcinoma of Bladder

    […] factors cyclophosphamide (a chemotherapy agent) increases the risk of bladder transitional cell carcinoma with a dose-response pattern 8 aromatic amines in tobacco smoke arylamines[radiopaedia.org] Arylamines exposure used to be very high in Dye, Rubber, Aluminum, Leather industry workers along with truck drivers and pesticide applicators but most arylamines usage has[disabled-world.com] An environmental risk is presented by a class of organic chemicals called arylamines .[britannica.com]

    Missing: Acetylases
  • Mycobacterium Smegmatis

    Arylamine N-acetyltransferase is an enzyme that is conserved in most Mycobacterium spp.[ncbi.nlm.nih.gov] Abstract MSMEG_0307 is annotated as a transcriptional regulator belonging to the AraC protein family and is located adjacent to the arylamine N-acetyltransferase (nat) gene[ncbi.nlm.nih.gov]

    Missing: Acetylases
  • Aminoglutethimide

    Previous studies have shown that arylamine metabolism by MPO results in protein radical formation.[ncbi.nlm.nih.gov] Siraki Canadian Journal of Physiology and Pharmacology 2013 91 (3), 228-235 Free Radical Metabolites in Arylamine Toxicity Arno G.[doi.org] HL-60 cells contain abundant amounts of myeloperoxidase (MPO), a hemoprotein, which catalyzes one-electron oxidation of arylamines using H2O2 as a cofactor.[ncbi.nlm.nih.gov]

    Missing: Acetylases
  • Toxic Oil Syndrome

    Genotype analyses were performed to assess the metabolic capacity of phase I [cytochrome P450 1A1 (CYP1A1), CYP2D6] and phase II [arylamine N-acetyltransferase-2 (NAT2), GSTM1[ncbi.nlm.nih.gov] Abstract The most basic arylamine, aniline, belongs to a class of compounds notorious for inducing allergic and autoimmune reactions.[ncbi.nlm.nih.gov]

    Missing: Acetylases

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