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652 Possible Causes for Acetylcholine, Antibody:Arbitrary, Concentration:Point, IN, receptor, time:Serum:Ordinal

  • Tubocurarine

    Abbreviations: nAChR acetylcholine receptor ACh acetylcholine ECS extracellular solution Received March 19, 2001. Accepted July 3, 2001.[molpharm.aspetjournals.org] The intensity of fasciculations and intubating conditions were assessed using a four-point rating scale.[ncbi.nlm.nih.gov] The mechanograms were divided by an arbitrary straight line connecting the starting point of the contraction curve and the notch.[ncbi.nlm.nih.gov] An arbitrary straight line was drawn connecting the starting point of the contraction curve and the notch.[ncbi.nlm.nih.gov] Wild-type, chimeric, and point mutant 5-HT3A receptors were expressed in Xenopus oocytes, and two-electrode voltage clamp electrophysiological recordings were performed.[ncbi.nlm.nih.gov] De Da L implements several data pre-processing and layout post-processing steps such as continuous morphing between two arbitrary network layouts and aligning one network[science.gov]

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  • Urinary Tract Infection

    Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes . Proc. Natl Acad. Sci. USA 111 , 8287–8292 (2014). 51. Ratner, J.[doi.org] Armant MA, Fenton MJ (2002) Toll like receptors: a family of pattern recognition receptors in mammals. Genome Biol 3(8):3011.1–3011.6 CrossRef Google Scholar 8.[doi.org] OBJECTIVES: To investigate the effect of adding point-of-care (POC) susceptibility testing to POC culture on appropriate use of antibiotics as well as clinical and microbiological[ncbi.nlm.nih.gov] An arbitrary minimum number of ten studies is needed to perform funnel plot analysis and Egger tests to objectify publication bias.[doi.org] […] primary and secondary end points consistently with this guidance.[ncbi.nlm.nih.gov] Well-known steps in the pathogenesis of UTIs are urogenital colonization and adherence of uropathogens to uroepithelial cell receptors.[ncbi.nlm.nih.gov]

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  • Dementia

    The mainstays of current pharmacotherapy for AD are compounds aimed at increasing the levels of acetylcholine in the brain, thereby facilitating cholinergic neurotransmission[doi.org] Molecular cloning studies have identified three α 1 -adrenergic receptor subtypes (α 1A , α 1B , and α 1D ).[ncbi.nlm.nih.gov] We assessed change in the 30-point MMSE score over 2 years and the VAT score at 2 years-dichotomized as perfect (6 points) or imperfect ( 5 points)-and evaluated the predictive[ncbi.nlm.nih.gov] It was recognised at the time that these conditions had much in common, and that the cut‐off period of 12 months was arbitrary.[doi.org] Finally, the arbitrary age cut-off of the patients (more than 60 years of age) and the exclusion of reviews published before 2009 constitute other limitations of the present[doi.org] Two of the studies used a cut point of 22 to determine normal cognition ( Brayne 1989 ; Clarke 1991 ), one used a cut point of 23 ( Huppert 2005 ), and two used a cut point[doi.org]

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  • Anticholinergic

    Some bioactives in Traditional Chinese Medicine (TCM) are known to block acetylcholine receptors and thus potentially cause AA.[ncbi.nlm.nih.gov] The Muscarinic Acetylcholinergic Receptor ANTagonist Exposure (MARANTE) scale was tested for clinimetric properties using cohorts of community-dwelling older adults and nursing[ncbi.nlm.nih.gov] Outcome was judged based on an end-point of hospitalization or death. Kaplan-Meier survival and Cox proportional hazard analyses were performed.[ncbi.nlm.nih.gov] The rankings are somewhat arbitrary and controversial since some research categorizes these drugs differently. This is our best assessment at this time.[peoplespharmacy.com] Cultured CHO cells stably expressing M1 receptors M1WT3 were used.[ncbi.nlm.nih.gov] We found that both DM and its metabolite dextrorphan block nicotinic receptor function in a noncompetitive but reversible manner, suggesting that both drugs block the receptor[jpet.aspetjournals.org]

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  • Acute Bronchitis

    It has an antagonistic effect on muscarinic acetylcholine receptors.[doi.org] CC chemokine receptor 2 in the lung tissue of smokers and exsmokers with moderate-to-severe COPD.[doi.org] […] of mean BSS from 5.2 /-2.5 points to 1.2 /-2.1 points.[ncbi.nlm.nih.gov] Cerebral Blood Flow Supplementary Oxygen CaO2 Neonatal Resuscitation ... the aim of oxygen therapy should be to increase the delivery of oxygen rather than to reach any arbitrary[doi.org] Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled[ajrccm.atsjournals.org] The overall BSS score decreased during treatment from 6.0 /-3.0 points at baseline to 2.7 /-2.5 points after 7 days and to 1.4 /-2.1 points after 14 days.[ncbi.nlm.nih.gov]

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  • Decamethonium

    It is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor.[drugbank.ca] […] agonist An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. nicotinic acetylcholine receptor agonist An agonist that selectively binds[ebi.ac.uk] An arbitrary straight line was drawn connecting the starting point of the contraction curve and the notch.[ncbi.nlm.nih.gov] Fire Hazard Flash point data for this chemical are not available. It is probably combustible.[cameochemicals.noaa.gov] It is suggested that the first step in a depolarizing end-plate reaction is the formation of an intermediate, inactive, compound between drug and receptor.[rspb.royalsocietypublishing.org] Dexamethonium, which has a short action time, is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor .[chemeurope.com]

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  • Terfenadine

    Gene Name CHRM4 Uniprot ID P08173 Uniprot Name Muscarinic acetylcholine receptor M4 Molecular Weight 53048.65 Da References Yasuda SU, Yasuda RP: Affinities of brompheniramine[drugbank.ca] None of the histamine receptor blockers were found to modulate cell-cycle progression in neoplastic MCs.[ncbi.nlm.nih.gov] Abstract Torsades de pointes (TDP) is a ventricular tachycardia that can deteriorate into ventricular fibrillation.[ncbi.nlm.nih.gov] A marker (M1) was placed to set an arbitrary threshold between annexin-V-binding cells and control cells.[karger.com] Although found in many clinical settings, torsades de pointes is most often drug induced.[ncbi.nlm.nih.gov] […] commonly used over-the-counter antihistamines, brompheniramine and chlorpheniramine, as well as terfenadine in comparison with atropine at the five human muscarinic cholinergic receptor[ncbi.nlm.nih.gov]

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  • Neuromuscular Blocking Agent

    Acetylcholine receptor (AChR) - A protein that binds to the molecule acetylcholine.[paralytics.wikia.com] Infusion orders should identify either: Identify the titration end-point (such as "no spontaneous ventilation trigger", "no shivering" or "temperature 32-34C") Or Include[lhsc.on.ca] If the patient is paralyzed before a baseline mA dose can be established, choose an arbitrary mA dose of 20-40 mA, and always assess the patient at this mA level.[pharmacyjoe.com] Neuromuscular junction (NMJ) is the synapse which serves as the point where the nerve communicates with the muscles to stimulate contraction and movement.[nurseslabs.com] The tool was designed to be a quick summary of key points regarding the most commonly used neuromuscular blockers and is not meant to be exhaustive for every situation.[ebmconsult.com] Biotoxins include black widow spider venom, which depletes acetylcholine stores; botulinum toxin, which decreases acetylcholine release; tetradotoxin from the puffer fish[merckvetmanual.com]

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  • Thymectomy

    Although amyosthenia was absent, the patient's anti-acetylcholine-receptor antibody level was high, and she was positive for anti-desmoglein 3 antibodies.[ncbi.nlm.nih.gov] , Antigen, T-Cell/deficiency Receptors, Antigen, T-Cell/genetics Receptors, Antigen, T-Cell/immunology T-Lymphocytes, Regulatory/cytology T-Lymphocytes, Regulatory/immunology[ncbi.nlm.nih.gov] The end points improvement of MG and recurrence of thymoma are comparable to open procedures.[ncbi.nlm.nih.gov] […] perioperative deaths The early RR (44%) achieved after thymectomy had increased significantly by the end of the first year (72%, P Early and late RRs of 6 months and 1 year seem arbitrary[academic.oup.com] Compared to the sternotomy group, the video-assisted thoracoscopic thymectomy group had lower pain scores and morphine consumption at all time points, significantly less operative[ncbi.nlm.nih.gov] Her weakness improved with intravenous edrophonium administration.Initial binding acetylcholine receptor antibody titer was 1.22 nmol/L (normal value, 0.03 nmol/L).[ncbi.nlm.nih.gov]

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  • Atropine

    Atropine can be used to reduce the effect of the poisoning by blocking muscarinic acetylcholine receptors, which would otherwise be overstimulated, by excessive acetylcholine[en.wikipedia.org] 5-HT3 Receptor Antagonists/pharmacology Xenopus laevis Substances Muscarinic Antagonists Receptors, Serotonin, 5-HT3 Serotonin 5-HT3 Receptor Antagonists Atropine Scopolamine[ncbi.nlm.nih.gov] Intravenous atropine significantly increased HR at the 1-5 minute time points, mean arterial pressure at the 1-4 minute time points, and cardiac output at the 1-3 minute time[ncbi.nlm.nih.gov] […] studies showed that this permitted an accurate automatic computation of the average number of bursts in a time unit (minute) and of the average burst amplitude (expressed in arbitrary[dx.doi.org] RESULTS: Intraprocedural within-group comparison between the median of the 15-minute period before angioplasty and each of three single measure points with 5-minute intervals[ncbi.nlm.nih.gov] These provide evidence pointing to a combination of electrostatic and hydrophobic interactions as the driving forces for dendrimer complexation with the alkaloid drug molecule[ncbi.nlm.nih.gov]

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