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  • Lymphoblastic Lymphoma

    KEYWORDS: T-lymphoblastic lymphoma; adult; chemotherapy; childhood; treatment[] PROCEDURE: We used molecular inversion probe (MIP) technology to analyze and compare copy number alterations (CNAs) in archival formalin-fixed paraffin-embedded pediatric[] OBJECTIVES: This session of the 2013 Society of Hematopathology/European Association for Haematopathology Workshop was dedicated to B-acute lymphoblastic leukemia (B-ALL)[] We encountered a case of concurrent acute myeloid leukemia (AML) and T lymphoblastic lymphoma.[] Patients were treated according to the therapy protocol used for acute lymphoblastic leucemia.[] PURPOSE: We examined whether FDG PET can be used to predict outcome in patients with lymphoblastic lymphoma (LL).[] Publication type, MeSH terms Publication type Case Reports MeSH terms Acute Kidney Injury/complications Acute Kidney Injury/diagnosis* Acute Kidney Injury/pathology Cell Movement[] Primary/pathology* Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology* Sarcoma, Myeloid/genetics Sarcoma[] […] of chemotherapy and with radiotherapy of contralateral testis.[]

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  • Furazolidone

    Schnitzer , Frank Hawking Elsevier , 12 set 2013 - 632 pagine Experimental Chemotherapy, Volume II: Chemotherapy of Bacterial Infections: Part I is devoted to the history,[] BACKGROUND: Furazolidone-based regimens for the eradication of Helicobacter pylori are low cost and effective.[] Paterson CRC Press , 2 ott 2017 - 5338 pagine Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious[] […] drug therapy Leukemia, Myeloid, Acute/genetics Leukemia, Myeloid, Acute/pathology Oncogene Proteins, Fusion/genetics Oncogene Proteins, Fusion/metabolism Retroviridae/genetics[] Furazolidone was found to be efficacious, safe and cost-effective in the treatment of most cases of childhood typhoid fever caused by multi-resistant S. typhi.[] All the patients with duodenal ulcer (n 7) were successfully treated (100% vs 56.2% with antral nodularity).[] These results indicate that furazolidone, given as either a single dose or divided doses for 3 days, is effective treatment for childhood cholera.[] Various regimens including quadruple therapies have been recommended as rescue therapies after the first H. pylori eradication attempt failed.[] After we get the result of antibiotics sensitivity the patient will be divided randomly into two groups, Regimen A, Regimen B.[]

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  • Severe Acute Respiratory Syndrome

    This perspective focuses on the status of various efficacious anti-SARS-CoV 3CL(pro) chemotherapies discovered during the last 12 years (2003-2015) from all sources, including[] Co-infection and other treatable conditions should not be missed and conventional antibiotics should remain as part of the first-line treatment regimen.[] One of the most important findings was the use of inexpensive polyclonal IgY antibody to increase the sensitivity of the detection system for SARS-CoV at the picogram level[] The present study reports a case of SARS, which presented as acute abdomen, warranting laparotomy.[] We report the case of a woman who had undergone a successful allogeneic bone marrow transplant for acute myeloid leukemia.[] Large proportions of children and adults in Beijing have evidence of anti-S IgG against four the HCoVs, and first infections by all four non-SARS HCoVs takes place during childhood[] Pseudotyped virus carrying S protein (S-pseudovirus) produced by human cells that were treated with small interfering RNA (siRNA) for calnexin expression (calnexin siRNA-treated[] Different types of treatment regimens have been used for people who are severely ill and hospitalized including antibiotics, antivirals and steroids.[] Ruuskanen O, Mertsola J (1999) Childhood community-acquired pneumonia. Semin Respir Infect 14:163–172 PubMed Google Scholar 32.[]

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  • Bacillus Cereus

    Abstract A 5-year-old boy with standard-risk B-cell acute lymphoblastic anemia developed fever during induction chemotherapy. The patient had no neurological symptoms.[] Although B. cereus-induced meningoencephalitis is often lethal, the immediate treatment with a regimen of antibiotics including vancomycin was effective in eradicating the[] Abstract We report a case of rapidly progressive vision loss in a young woman with a history of injection drug use.[] We present an 11-year-old boy diagnosed as having acute encephalopathy and liver failure with the underlying condition of a metabolic dysfunction.[] Here we report an 8-year-old boy undergoing induction therapy for acute lymphoblastic leukemia who developed multifocal B. cereus cerebral abscesses, highlighting the propensity[] , Acute/complications* Leukemia, Myeloid, Acute/diagnosis Leukemia, Myeloid, Acute/drug therapy Lung/diagnostic imaging Male Middle Aged Neutropenia Pneumonia, Bacterial/complications[] We describe the clinical course of early-onset Bacillus cereus bacteremia in a preterm neonate who was successfully treated with vancomycin.[] Furthermore, multiple cases of fulminant septicaemia have been reported among individuals receiving chemotherapy for acute myelogenous leukaemia.[] Explantation of the shunt and addition of fosfomycin to the antibiotic regimen resulted in a complete cure of the infection.[]

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  • Acute Subdural Hematoma

    His peripheral white blood count normalized after Gleevec and hydroxyurea chemotherapy.[] RESULTS Of 116 patients, 74 (64%) had been following an OAT regimen at presentation with aSDH.[] For linear acceleration, the posterior-anterior direction showed the greatest force (41.0 2.6 G using Osoto-gari, and 86.5 4.3 G using Ouchi-gari).[] […] left-sided subdural hematoma with midline shift shortly after craniotomy for evacuation of a traumatic right-sided acute subdural hematoma.[] In childhood, hematomas are a common complication of falls. A subdural hematoma also may be an indication of child abuse , as evidenced by shaken baby syndrome .[] Conclusion Historically, elderly patients with ASDH treated with a traditional craniotomy performed under general anesthesia have not had a good prognosis.[] Computed tomography revealed a high density lentiform lesion in the right convexity, which was thought to be acute epidural hematoma preoperatively.[] Univariate and multivariate logistic regression analyses were used to identify factors predictive of rapid spontaneous ASDH resolution.[] […] to recovery after surgical intracranial decompression, we reviewed the records of 82 consecutive comatose patients with traumatic acute subdural hematoma (ASDH) who were treated[]

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  • Human Parvovirus B19

    The present cross sectional study was designed to estimate the prevalence and genotype distribution of B19V in children receiving chemotherapy for solid malignancies at a[] (iv) A switch of the baseline immunosuppressive regimen may achieve a favourable curative effect. 2015 John Wiley & Sons Ltd.[] B19 DNA quantitative analysis was performed using real-time PCR while screening for IgM and IgG anti-B19 antibodies was performed using ELISA.[] Abstract Parvovirus is a rare cause of acute hepatitis. Two children with non A-E acute hepatitis in whom human parvovirus B19 was detected by PCR are reported.[] Children with aplastic anemia/leukemia/chronic hematological disorders, and healthy blood donors were enrolled in the study.[] It was concluded that this patient represents the first published case of childhood chorea-encephalopathy associated with, and probably caused by, human parvovirus B19 infection[] These include cytopenias affecting the erythroid, megakaryoblastoid, myeloid and lymphoid lineages, as well as a variety of bicytopenias, pancytopenia, bone marrow necrosis[] treated with rabbit anti‑B19‑NS1 and anti‑B19‑VP2 IgG, as compared with the control group.[] Syndromes predisposing to persistent B19 viraemia and PRCA include acquired immunodeficiency syndrome (AIDS), 47 chemotherapy for acute lymphoblastic leukaemia, 129 acute[]

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  • Neostigmine

    We report a 9-year-old boy with acute colonic pseudo-obstruction caused by chemotherapy for brain tumor who did not respond to initial supportive therapy, but who was successfully[] The patient was initially diagnosed with adynamic ileus and treated conservatively with bowel rest, reduction in narcotic dosage, and a regimen of stool softeners, laxatives[] A combination of artificial respiration and neostigmine has been useful in resuscitating a child bitten by a snake.[] OBJECTIVE: To review the literature on the safety and effectiveness of neostigmine for the treatment of postoperative acute colonic pseudo-obstruction.[] It is characterized by signs of large-bowel obstruction, without a mechanical cause, and has been reported in various settings, including acute leukemias as a complication[] We report the first pediatric case of acute pseudoobstruction secondary to sickle cell disease that was treated successfully with neostigmine.[] Group 2 constituted patients who had a poor first response to colonoscopic decompression, and neostigmine was added to the treatment regimen.[] However, experience in using neostigmine for this indication in pregnant women is limited.[] We present two poisoning cases in which neostigmine was used to facilitate gut decontamination complicated by ileus.[]

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  • Peripheral T-cell Lymphoma

    Development and persistence of corneal infiltration despite systemic chemotherapy may be a warning sign for resistance to treatment.[] The primary endpoint was the overall response rate (ORR); secondary endpoints were survival, duration of response, and safety of the regimen.[] Patient-level healthcare resource utilization data and associated costs (in US dollars) were measured. Mean costs per patient per month were determined.[] We highlight the potential pitfall of acute EBV masquerading as PTCL and show the critical role of the multidisciplinary integration of histopathological, serology, molecular[] A splenectomy revealed T-LGL leukemia.[] However, CM , EBV-associated PTCL is extremely rare in the childhood, with only 1 study having been reported to date, including both pediatric and adult patients.[] Abstract Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm underlain by the formation of BCR-ABL1 - an aberrant tyrosine kinase - in the leukaemic blasts.[] METHODS: Patients with PTCL relapsed/refractory to 1 prior therapy were treated with the approved dose of 14 mg/m(2) romidepsin on days 1, 8, and 15 of six 28-day cycles;[] PTCLs are a heterogeneous and rare group of childhood NHLs.[]

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  • Moxifloxacin

    PURPOSE: Patients receiving intensive chemotherapy regimens are at high risk for infectious complications due to prolonged neutropenia and hospital stay.[] Regimens of standard linezolid and moxifloxacin plus faropenem T MIC 60%, as well as higher-dose moxifloxacin, achieved slopes equivalent to those of the standard regimen[] In this patient, ATIN was likely associated with moxifloxacin use.[] We suggest close follow-up to investigate the efficacy of moxifloxacin for treating M. genitalium infections.[] Recruiting Treatment Helicobacter Infection 2 Not Available Terminated Supportive Care Chronic Myeloproliferative Disorders / Fever, Sweats, and Hot Flashes / Infection NOS / Leukemias[] Abstract Control of multi-drug-resistant tuberculosis (MDR-TB) requires extensive, supervised chemotherapy because second-line anti-TB drugs have a narrower therapeutic range[] The use of second-line drugs not approved for use in children may be necessary to treat a life-threatening disease such as MDR TB, but it requires careful monitoring to quickly[] Increasing experience with well-absorbed, well-tolerated and highly active agents such as the new quinolones has prompted interest in their use as therapeutic alternatives[] BACKGROUND: Acute interstitial nephritis (AIN) is an important cause of reversible acute kidney injury.[]

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  • Cantharidin

    ; and the control group receiving only chemotherapy.[] The systematic analysis suggested that, in all patients, pooled RR was 46.5% (72/155) in cantharidin combined regimens.[] The purpose of this study was to determine the breadth of usage of cantharidin, most frequently used protocols, and common side effects seen with use of cantharidin.[] The ultimate prognosis is good with regard to renal function if the patient survives the acute phase [ 2 ].[] , Myelogenous, Chronic, BCR-ABL Positive/drug therapy* Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism[] CONCLUSION: To our knowledge ours is the largest retrospective series of childhood MC treated with cantharidin.[] There are several lesions and growths of the skin that can be treated with Cantharidin.[] […] molluscum contagiosum and give detailed information about distribution sources, how to apply it, and caveats regarding its use.Molluscum contagiosum is a common viral disease of childhood[] This regimen resulted in 90% of lesions clearing in 12 patients, with half of these being totally clear. Two patients had 80-90% of lesions resolve.[]

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