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  • Anisakis

    A. simplex (s.s.) larvae from chub mackerel tolerated the artificial gastric juice better than A. pegreffii, with 50% mortality in 2.6 and 1.4 days, respectively.[ncbi.nlm.nih.gov] The molecular identification of the etiological agent at the species level allows to identify what Anisakidae species play a zoonotic role and which are the fish host species[ncbi.nlm.nih.gov] RESULTS: Both Anisakis products led to increased production of reactive oxygen species (ROS), especially in EC-treated cells.[ncbi.nlm.nih.gov] In 4/17 patients, an increase in specific IgE level with the introduction of fish to the diet was observed.[ncbi.nlm.nih.gov] The experience with the fish parasite Anisakis simplex-associated allergic features still nurtures an open debate on the necessity of larvae being alive to induce allergic[ncbi.nlm.nih.gov] However, a concern in the raw sea food industry is that the parasitic nematode Anisakis simplex L3 occurs naturally in marine fish.[ncbi.nlm.nih.gov] In contrast, very limited molecular associations with other parasite groups are observed, including trematodes and cestodes.[ncbi.nlm.nih.gov] BACKGROUND: Serine proteinase inhibitors (serpins) finely regulate serine proteinase activity via a suicide substrate-like inhibitory mechanism.[ncbi.nlm.nih.gov] Anisakis larvae are resistant to the thermal or biocidal agent treatments.[ncbi.nlm.nih.gov] One cDNA clone, designated as α-methylacyl CoA racemase (Amacr) contained a 1,412 bp cDNA transcript with a single open reading frame that encoded 418 amino acids.[ncbi.nlm.nih.gov]

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  • Methicillin-resistant Staphylococcus Aureus

    The patient underwent surgery for the removal of the artificial left knee joint and placement of vancomycin-impregnated bone cement beads against methicillin-resistant S.[ncbi.nlm.nih.gov] RESULTS: The isolates showed good susceptibility to all five anti-MRSA agents; only five sporadic non-susceptible isolates were detected.[ncbi.nlm.nih.gov] Methods: This is a cross sectional study of the prevalence of LA-MRSA among hospital staff in a Danish hospital situated in a livestock production region.[ncbi.nlm.nih.gov] INTRODUCTION: With the advancement of medicine and surgery, various types of medical devices have become part of treatment strategies.[ncbi.nlm.nih.gov] The recently developed PCR-based open reading frame typing (POT) method is a useful molecular typing tool.[ncbi.nlm.nih.gov] BACKGROUND: Although most reports describing patients infected with methicillin-resistant Staphylococcus aureus enterocolitis have been published in Japan, this concept remains[ncbi.nlm.nih.gov] In conclusion, this study investigated the nature of RIF-R in Italy among RIF-R-MRSA strains, finding a prevalence of ST228, strongly associated with reduced susceptibility[ncbi.nlm.nih.gov] In contrast, sphingomyelin liposomes harboring a high cholesterol content (66 mol/%) were unable to protect human cells from phenol-soluble modulin-α3-induced lysis, however[ncbi.nlm.nih.gov] OBJECTIVE: Assess risk factors for MRSA colonization in NICUs via a systematic review and meta-analysis.[ncbi.nlm.nih.gov] INTRODUCTION: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) colonization and infection are increasingly being reported worldwide and are associated[ncbi.nlm.nih.gov]

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  • Aging

    RESULTS: While stored in artificial saliva, acid and ethanol the CA decreased especially for the low- and medium-filled composites.[ncbi.nlm.nih.gov] KEYWORDS: Antiplatelet agents; Arterial thrombosis; Bleeding; Cardiovascular risk factors; Factor VII deficiency[ncbi.nlm.nih.gov] Introduction: The relationship between cognition and the ability to hear is well known.[ncbi.nlm.nih.gov] Access Journals (DOAJ) OAIster : The Open Access Initiative Related journals you may also be interested in:[dovepress.com] Abstract The concept of "successful aging" is a contested discourse in gerontology.[ncbi.nlm.nih.gov] Observations about the natural history of aging in Cornelia de Lange syndrome (CdLS) are made, based on 49 patients from a multidisciplinary clinic for adolescents and adults[ncbi.nlm.nih.gov] In striking contrast to the difficulties with new learning and episodic memories in aging and especially in Alzheimer's disease (AD), musical long-term memories appear to[ncbi.nlm.nih.gov] The engulfment of PLTs assisted in delaying the aging of endothelial cells via girdin and p‑girdin, in which the AKT signal was involved.[ncbi.nlm.nih.gov] 30 am - 8:30 am Breakfast 9:00 am - 12:30 pm Fragility in Aging: Mitochondria and ER Discussion Leader: Daniel Promislow (University of Washington, USA) 9:00 am - 9:10 am Introduction[grc.org] Senescence-associated-β-galactosidase (SA-β-Gal) activity was assessed as a marker of natural senescence.[ncbi.nlm.nih.gov]

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  • Influenza Virus

    Both patients were improved by artificial ventilation with positive end-expiratory pressures and administration of broad spectrum antibiotics and corticosteroids before confirming[ncbi.nlm.nih.gov] […] recognize conserved epitopes within the influenza virus hemagglutinin (HA) stalk domain are of particular interest for their potential use as therapeutic and prophylactic agents[ncbi.nlm.nih.gov] MDCK-SIAT1 cells were transduced to express Ebolavirus glycoprotein as a stable transmembrane protein for E-S-FLU virus production.[ncbi.nlm.nih.gov] Abstract Introduction of influenza viruses with gene segments of avian origin into the human population may result in the emergence of new pathogenic human influenza viruses[ncbi.nlm.nih.gov] Seiya Yamayoshi & Yoshihiro Kawaoka Research 28 January 2019 open Ian Shannon , Chantelle L. White , Amy Murphy , Xing Qiu , John J. Treanor & Jennifer L.[nature.com] Altogether, these results show that FPR2signaling interferes with the endosomal trafficking of influenza viruses and provides, for the first time, the proof of concept that[ncbi.nlm.nih.gov] We previously showed that a naturally occurring deletion (the EALQR motif) in the NS1 effector domain of an H5N1 swine-origin avian influenza virus impairs the inhibition[ncbi.nlm.nih.gov] In contrast, secondary infection of H1N1 preimmune ferrets with an antigenically distinct H1N1 virus elicited a recall response against the original HA that was no longer[ncbi.nlm.nih.gov] In conclusion, CIV H3N2 induced the upregulation of cfa-miR-143, which contributes to apoptosis via indirectly activating the p53-caspase3 pathway.[ncbi.nlm.nih.gov] The third required support by an artificial heart, and died 8 mo later.[ncbi.nlm.nih.gov]

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  • Bicarbonate

    METHODS: Fourteen subjects who wore mandibular removable partial dentures embedded with bovine enamel blocks with artificial enamel lesions were included.[ncbi.nlm.nih.gov] Sodium bicarbonate may be an effective mucolytic agent for PMP.[ncbi.nlm.nih.gov] Drying/Sieving After drying separated sodium bicarbonate, it is then arranged by particle size using a sieving process and turned into a product. AGC Inc.[agc-chemicals.com] INTRODUCTION: Chronic Renal Failure (CRF) patients are considered to show genomic instability and are associated with a high risk of both cardiovascular diseases and cancer[ncbi.nlm.nih.gov] METHODS: We did a multicentre, open-label, randomised controlled, phase 3 trial.[ncbi.nlm.nih.gov] The concept of 'total buffer' that assumes that the combination of bicarbonate and acetate concentrations in the dialysate are added equally as bicarbonate equivalents is[ncbi.nlm.nih.gov] Use baking soda to clean your kitchen Stop smelly trainers with bicarb Soothe a sore throat naturally with baking soda Use bicarb to kill weeds in your garden Make natural[yours.co.uk] Radiographic contrast agent iohexol was used.[ncbi.nlm.nih.gov] Bicarbonate administration via the dialysate helps maintain the acid-base balance in these patients.[ncbi.nlm.nih.gov] […] to the final dialysis fluid, will have a better knowledge of the amount of bicarbonate and bicarbonate precursors delivered to the patient. 2017 International Center for Artificial[ncbi.nlm.nih.gov]

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  • Ketamine

    Abstract The implantation of total artificial hearts (TAH) via midline sternotomy for the treatment of severe biventricular cardiac dysfunction is associated with complex[ncbi.nlm.nih.gov] Given the unique side effect profile of ketamine, it is imperative that information is disseminated on potential utilization of this agent.[ncbi.nlm.nih.gov] Formulation: A neat solid Description Features This product has been manufactured and tested to meet ISO/IEC 17025:2005 and ISO Guide 34:2009 specifications This product is[caymanchem.com] Only on reduction of the ketamine dose and introduction of additional antihypertensive medication, did her BP normalise.[ncbi.nlm.nih.gov] Twelve ketamine treatments were given in the open-label phase. Mood, hemodynamic, and psychotomimetic outcomes were assessed by blinded raters.[ncbi.nlm.nih.gov] In conclusion, this proof-of-concept trial provides initial evidence that ketamine may be effective in reducing anxiety.[ncbi.nlm.nih.gov] Further research is required to elucidate the natural course of depression after ketamine withdrawal.[ncbi.nlm.nih.gov] Here, we show that memantine and ketamine have contrasting effects on NMDAR desensitization.[ncbi.nlm.nih.gov] If they are not breathing, begin artificial (mouth-to-mouth) respiration. Ketamine is illegal and possession can result in long prison terms.[dancesafe.org] Evidence of widespread cytokeratin 13, basal p75(NTR), and sparse superficial uroplakin 3a immunoreactivity suggested the urachal epithelium was fundamentally transitional in nature[ncbi.nlm.nih.gov]

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  • Echinococcus Multilocularis

    This model can be trained with a high class imbalance and without the artificial definition of a negative class.[ri.conicet.gov.ar] Author information 1 Institute of Parasitology, University of Zurich, Zurich, Switzerland. [email protected] Abstract Echinococcus multilocularis, the causative agent[ncbi.nlm.nih.gov] Using an in vitro T-cell stimulation assay, we found that primary cell E/S products promoted interferon (IFN)-γ release by murine CD4 T-cells, whereas metacestode E/S products[ncbi.nlm.nih.gov] Molecular epidemiological techniques are a useful tool for detecting and tracing introductions, and differentiating these from range expansions.[ncbi.nlm.nih.gov] The recent sequencing of E. multilocularis and E. granulosus genomes opens new possibilities for performing in-depth phylogenetic analyses.[ncbi.nlm.nih.gov] KEYWORDS: Echinococcus multilocularis; animal model; fluorescent imaging; in vivo MeSH terms, Substances, Supplementary concept MeSH terms Albendazole/pharmacology* Animals[ncbi.nlm.nih.gov] Science Foundation of China/ No. 32571231/National Natural Science Foundation of China/ No. 2015-ZJ-745/The Provence Natural Science Foundation of Qinghai/ No. 2016-wjzd-[ncbi.nlm.nih.gov] These contrasted outcomes suggest that the frequency of fox anthelmintic treatment should be adapted to the local situation. Copyright 2013 Elsevier B.V.[ncbi.nlm.nih.gov] Trials to counteract the spread of this parasite have been performed by application of anthelmintics to foxes via baits, and gave encouraging results on different spatial[ncbi.nlm.nih.gov] The findings show that the Em2 ELISA may be positive in patients having lesions of AHD in which the etiologic agent is no longer viable.[ncbi.nlm.nih.gov]

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  • Trichinella Spiralis

    The artificially infected rats were sacrificed on 42nd day after the infection and meat was examined by the following methods--artificial digestion and trichinoscopy.[ncbi.nlm.nih.gov] Therefore, this mAb is a protective antibody that has potential as a preventive and therapeutic agent for T. spiralis infection.[ncbi.nlm.nih.gov] As indicators of DC maturation, the cytokine production (IL-1alpha, IL-6, IL-10, IL-12p70 and TNF-alpha) and the expression of various surface molecules (MHC-II, CD40, CD80[ncbi.nlm.nih.gov] Introduction: Trichinosis (also called trichinellosis) is caused by nematodes (roundworms) of the genus Trichinella.[genwaybio.com] The open reading frame of Ts-Hsp70 cDNA encoded a 623-amino acid peptide with a predicted molecular weight of 68.7kDa, which shares a high degree of sequence conservation[ncbi.nlm.nih.gov] Hence arises the concept that helminths strongly influence the immune system and enable protective pathways against these hyperimmune-associated disorders.[ncbi.nlm.nih.gov] From the above findings, it was confirmed that T. spiralis is present in Korea, and the badger plays a role of as the natural host.[ncbi.nlm.nih.gov] Studies performed in placentas and umbilical cords by artificial digestion and/or immunofluorescence did not reveal the presence of parasites or parasite antigens.[ncbi.nlm.nih.gov] Historical Introduction. Trichinella and trichinellosis. 1983. (Campbell, WC, ed.). Plenum Press, Pubs, New York pages. 1-30. CDC.[web.stanford.edu] The enzyme cDNA was cloned and sequenced, allowing the characterization of a single open reading frame of 307 amino acids coding for a putative protein of 35,582 Da molecular[ncbi.nlm.nih.gov]

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  • Rabies Virus

    In monoclonal antibodies, the VH and VL interact non-covalently, while in scFvs the VH is connected covalently with the VL by the artificial linker.[ncbi.nlm.nih.gov] The results of both computational and experimental methods demonstrated that nAChRα1 peptides and their analogs may serve as potential antiviral agents against RABV infection[ncbi.nlm.nih.gov] Select up to 5 products from below to compare or request more information.[biocompare.com] Phylogenetic reconstructions show that the currently circulating RABV lineages in Yunnan result from at least seven independent introductions (95% BCI: 6-9 introductions)[ncbi.nlm.nih.gov] METHODS: We conducted a phase I, open label, randomized study in healthy adults to assess the safety and immunogenicity of the PIKA Rabies vaccine and an accelerated vaccine[ncbi.nlm.nih.gov] It has long been held that a rabies infection is lethal in humans once the causative RABV reaches the central nervous system (CNS); however, this concept was challenged by[ncbi.nlm.nih.gov] Abstract Rabies virus glycoprotein (RVG), a 505 amino acid type-1 glycoprotein, is responsible for the neurotrophic nature of the rabies virus infection.[ncbi.nlm.nih.gov] (M-Tha) was previously shown to be able to interact with RelAp43, a protein of the NF-κB family, and to efficiently suppress NF-κB-dependent reporter gene expression, in contrast[ncbi.nlm.nih.gov] Results showed that these pathways were highly activated; misfolded RABV-G was degraded in the cytosol via the ERAD mechanism.[ncbi.nlm.nih.gov] INTRODUCTION: After 29 years, rabies was detected in a cat in Curitiba, southern Brazil.[ncbi.nlm.nih.gov]

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  • Pneumonia

    PATIENTS AND METHODS: Materials and methods: A prospective cohort randomized clinical study was organized, particularly artificial ventilation of the lungs was conducted on[ncbi.nlm.nih.gov] METHODS: We did a systematic review using PRISMA methodology to identify the main etiological agents in Brazilian NICUs.[ncbi.nlm.nih.gov] Patients should specifically be asked about lipid-based over-the-counter products and cosmetic agents. Copyright 2017 American Pharmacists Association .[ncbi.nlm.nih.gov] INTRODUCTION: Ventilator-associated pneumonia (VAP) is frequent in Intensive Care Unit (ICU) patients.[ncbi.nlm.nih.gov] METHODS: In this multi-centric, controlled, open-labeled phase 3 trial, adult patients with PORT risk III-IV CAP were randomized to receive either intravenous CSE-1034 (3g[ncbi.nlm.nih.gov] BACKGROUND: The concept of sepsis was redefined recently, and a new screening system termed the quick Sequential Organ Failure Assessment (qSOFA) was recommended for identifying[ncbi.nlm.nih.gov] This is more likely to occur if your immune system is weak due to injury or illness or if your natural airway has been bypassed by a tracheostomy tube.[craighospital.org] The rMPV-RSV-F vectors expressing RSV F from the first, third, or fourth gene position were genetically stable and were not restricted for replication in vitro In contrast[ncbi.nlm.nih.gov] Abstract Smoking heroin (chasing the dragon), is a method of inhaling heroin via heating the drug on a tin-foil above a flame.[ncbi.nlm.nih.gov] Since both patients had an infection and temporarily elevated B12, we suggest a possible inflammatory response or a vitamin B12 production by the infectious agents as the[ncbi.nlm.nih.gov]

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