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92 Possible Causes for Agents,, Antimutagenic

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  • Phenothiazine

    The chemical structure of phenothiazine provides a most valuable molecular template for the development of agents able to interact with a wide variety of biological processes[] These compounds did not show any apparent mutagenic activity, but rather be antimutagenic.[] […] that phenothiazines reduce the incidence of cancer in humans generated a broad range of experimental studies, which confirmed their antitumor, cancer-chemopreventive and antimutagenic[]

  • Croton

    Studies on active principles of plant have motivated researchers to develop new antitumor agents that are specific and effective for treatment of neoplasms.[] The mutagenic and antimutagenic activity of C. lechleri sap was examined by means of the Ames/Salmonella test.[] While experimental latency reversal agents (LRAs) can promote HIV expression in these cells, thereby exposing them to immune recognition, existing LRAs exhibit limited clinical[]

  • Lilium

    Organisms are constantly exposed to the detrimental effect of environmental DNA-damaging agents.[] One of the modern approaches to reduce the mutagenic burden is based on exogenous natural and synthetic compounds that possess protective and antimutagenic potential against[]

  • Dendrobium

    In conclusion, our study suggested that endophytic fungi of D. officinale are great potential resources to discover novel agents for preventing or treating pathogens and tumors[] Gigantol isolated from Dendrobium nobile has shown antimutagenic properties.[] These findings demonstrate the potential of isoviolanthin as a therapeutic agent for the treatment of advanced-stage metastatic HCC.[]

  • Momordica Charantia

    Results reveal that the mode of action of these newly found antileishmanial agents is mediated through inhibiting parasite SOD which is one of the key enzymes of the oxidative[] […] activities of M. charantia have been reported, such as antihyperglycemic, antibacterial, antiviral, antitumor, immunomodulation, antioxidant, antidiabetic, anthelmintic, antimutagenic[] All these findings suggest the potential application of PEGylated α-MMC and PEGylated MAP30 as antitumor and antivirus agents.[]

  • Honey

    Based on these results, the authors advised honey as a new agent for split thickness skin graft fixation.[] antimutagenicity.[] Furthermore, it can be used as an antibacterial agent to reduce the ocular flora.[]

  • Atorvastatin

    […] alkylating agents of DNA.[] Background In patients with stable coronary artery disease, aspirin, a statin, and an angiotensin-converting enzyme inhibitor are recommended as first-line agents for secondary[] This is known as a 'paradoxical HDL-C decrease' as both groups of agents usually increase HDL-C.[]

  • Capsaicin

    These results suggest that 68Ga-SCN-Bn-DOTA-capsaicin is a potential targeting agent for PET imaging of MCF-7.[] […] genotoxic except green hot pepper and capsaicin at the highest tested concentration (5 mg/mL and 11.5 μM respectively), ii) all tested substances except green hot pepper are antimutagenic[] Sensory System Agents Peripheral Nervous System Agents Physiological Effects of Drugs[]

  • Quinacrine

    With 1 Figure 699 Subject Index 719 Urheberrecht Häufige Begriffe und Wortgruppen Bibliografische Informationen Titel Mechanism of Action of Antimicrobial and Antitumor Agents[] We suggest that these antimutagenic effects of quinacrine could be possibly attributed, at least in part, to its ability to block the bioactivation of NNK, mainly by the inhibition[] Our results suggest that the administration of quinacrine in combination with chemotherapeutic agents and targeted agents should be further explored in patients with recurrent[]

  • Belamcanda Chinensis

    Phytoestrogens (50 microM) combined with bicalutamide (10 microM) further decreased the number of RWPE-1 and PC-3 cells compared to these agents alone.[] In addition to the antimutagenic activities of these compounds against furylfuramide, Trp-P-1 and activated Trp-P-1 were also assayed by an Ames test using S. typhimurium[] The downregulation of PDEF, PSA, hTERT and IGF-1 receptor gene expression by tectorigenin demonstrates the antiproliferative potential of these agents.[]

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