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261 Possible Causes for Agonist,, H3, Histamine

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  • Neuroblastoma

    Abstract In stably-transfected human neuroblastoma SH-SY5Y cells, we have compared the effect of activating two isoforms of 445 and 365 amino acids of the human histamine[] , but not by the agonists R-α-methylhistamine and immepip or the antagonists/inverse agonists ciproxifan and A-331440.[] The synergism of treatment of cells with VPA and ellipticine seems to be connected with increased acetylation of histones H3 and H4.[]

  • Dopamine

    BACKGROUND: Clobenpropit, a potent antagonist/inverse agonist at the histamine H 3 receptor (H 3 R), reduced the cytotoxic action of 6-hydroxydopamine (6-OHDA) in neuroblastoma[] RESULTS: Neutropenia was recurrent after changing to various different dopamine agonists necessitating surgical treatment of a prolactinoma.[] This monoamine chain can be found in many neurotransmitters, including histamine , serotonin , adrenaline and noradrenaline .[]

  • Terfenadine

    We have therefore studied the effect of terfenadine (an H1-histamine receptor antagonist) in prostate cancer cell lines.[] ] External links [ edit ] Hoechst Marion Roussel Committed to Education Regarding Seldane Usage , an April 30, 1996 press release v t e Histamine receptor modulators H 1 Agonists[] Abstract The effects of ebastine and terfenadine, long-acting nonsedating histamine H1 receptor antagonists, were studied on hKv1.5 channels using the whole-cell voltage-clamp[]

  • Sophora

    SFA (200mg/kg) inhibited the mast cell-mediated passive cutaneous anaphylaxis reaction in vivo and the release of histamine from rat peritoneal mast cells by compound 48/80[] Furthermore, the genistein and DCM fractions similarly modulated the expression of estrogen target genes and were both active in transfection assays that measured estrogen agonistic[] This occurs via attenuation of extracellular signal-regulated protein (ERK) and RSK2 kinase pathways and inhibition of S6 kinase ribosomal protein (S6RP) and histone H3 S10[]

  • Astemizole

    DESIGN: They first underwent three inhalation tests and skin prick tests with histamine on three different days.[] The requirements of beta-agonist inhalations and the number of bronchospasm episodes were recorded throughout the study period.[] Abstract Polycomb Repressive Complex 2 (PRC2) modulates the chromatin structure and transcriptional repression by trimethylation lysine 27 of histone H3 (H3K27me3), a process[]

  • Sulfone

    Author information 1 Arena Pharmaceuticals, 6166 Nancy Ridge Drive, San Diego, CA 92121, USA. [email protected] Abstract The design of a new clinical candidate histamine-H[] Abstract A series of novel, potent, and selective human β2 adrenoceptor agonists incorporating a sulfone moiety on the terminal right-hand-side phenyl ring of (R)-salmeterol[] Species: Human Sample Types: Protein Applications: Bioassay Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation Authors: L Yamaguchi, A Nishiyama[]

  • Bruxism

    Complex and poorly understood interactions between multiple central nervous system neurotransmitters, such as histamine, serotonin, and dopamine, are involved.[] The dopamine agonist pramipexole is currently indicated for the symptomatic treatment of restless legs.[] Centre-ville, Montréal, Québec H3 C 3J7, Canada. 3 Department of Oral Treatment and Clinical Education, Tokushima University Hospital, 3-18-15 Kuramoto-cho, Tokushima 770-[]

  • Sulfonamide

    AMG8379 dose-dependently inhibited intradermal histamine-induced scratching and intraplantar capsaicin-induced licking, and reversed UVB radiation skin burn-induced thermal[] In contrast to intepirdine (SB-742457), which prevented 5-HT 6 R-elicited neurite growth and behaved as an inverse agonist of cyclin-dependent kinase 5 (Cdk5), compound 17[] Further, their target modulating effect, measured as the expression of acetyl-H3 histone and acetyl α-tubulin was determined by Western blots.[]

  • Dementia with Lewy Bodies

    This comparative ligand autoradiographical study has quantified histamine H 3 receptors (H 3 R) in a series of major cortical and basal ganglia structures in human DLB and[] KEYWORDS: DLB; Parkinson's disease; dopaminergic agonist; psychiatric symptoms; visual hallucinations [Indexed for MEDLINE] Free full text[] […] dementia appears later in the disease memory deficits seen early in Alzheimer's disease visual hallucinations parkinsonism fluctuations in cognition Poor response to dopamine agonist[]

  • Dexamethasone

    Abstract Conessine, a steroidal alkaloid, is a potent histamine H3 antagonist with antimalarial activity.[] (against FGF23) FGFR4 Agonists: Ersofermin FGF ( 1 , 2 (bFGF) , 4 , 6 , 8 , 9 , 19 ) Trafermin Unsorted Agonists: FGF15/19 HGF (c-Met) Agonists : Hepatocyte growth factor[] ), R848 (TLR7/8 agonist) or LPS/adenosine triphosphate (ATP) (inflammasome induction).[]