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193 Possible Causes for Allele, B2M, wt

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  • Uremia

    We investigated whether B2M is proinflammatory by inducing oxidative burst in leukocytes.[] The parathyroid phenotype and serum chemistries of wild-type (WT) and transgenic mice were examined after 14 weeks of either sham operation or 75% renal mass reduction (NX[] These HLA-DRB1 alleles may be closely associated with uremia.[]

  • Scoliosis

    […] included N-acetyl-beta-D-glucosaminidase (NAG), urine microalbumin, serum transferrin, immunoglobulin G (IgG), urinary alpha-1-microglobulin (A1M), and beta-2-microglobulin (B2M[] Morpholino-induced rps6ka3-knockdown in zebrafish embryos led to body curvature, which was reversed by WT RPS6KA3 mRNA.[] The polymorphic T allele and TT genotype were associated with a greater incidence of IS and can be considered as predisposing factors with a moderate effect on deformity development[]

  • B-Cell Chronic Lymphocytic Leukemia

    Serum levels of beta-2-microglobulin (B2M) and lactate dehydrogenase (LDH) and blood WBC, RBC, Plt and ESR were measured.[] In addition, B cells from TCL1 transgenic mice showed a significant decrease in DNA methylation compared with WT controls.[] These findings suggest that this is a case of B-CLL lacking allelic exclusion and undergoing a class switch of one allele with the incomplete expression of the VH gene.[]

  • Mast Cell Leukemia

    Fusion analysis was performed using WTS data, possibility of RARα-B2M fusion has been arised. However, it was not validated by PCR sequencing.[] Sequencing of whole coding region of c-kit cDNA revealed that c-kit genes of HMC-1 cells were composed of a normal, wild-type allele and a mutant allele with two point mutations[] Sequencing of c-kit cDNA revealed that c-kit genes of HMC-1 cells were composed of a normal, wild-type allele and a mutant allele with two point mutations in codon 560 and[]

  • Pulmonary Edema

    Seven candidate reference genes (RPL13A, YWHAZ, GUSB, SDHA, GAPDH, B2M, and ACTB) were evaluated in the lung by the geNorm module in qBase plus software.[] [cited 2017 Mar 1] Krum H, Abraham WT. Heart failure. Lancet 2009;373:941-55.[] However, there is no significant difference in the genotype frequency and allele frequency between patients with HAPE and healthy subjects without HAPE.[]

  • Indomethacin

    For KIM-1, B2M and NGAL, antibodies were obtained from R&D Systems (Minneapolis, MN, intra-assay CV 7.4%, 9.7% and 6.8%, respectively).[] Wt 357.79 Formula C 19 H 16 ClNO 4 Storage Store at RT Purity 99% (HPLC) CAS Number 53-86-1 PubChem ID 3715 InChI Key CGIGDMFJXJATDK-UHFFFAOYSA-N Smiles COC1 CC C2N(C( O)C3[] Among indomethacin responders, the G allele of rs2153628 and the T allele of rs1799853 were overtransmitted from the parents to their child (OR: 2.667, 95% CI: 1.374, 5.177[]

  • Avascular Necrosis of the Femoral Head

    Abstract This study aimed to evaluate 12 genes (18S, GAPDH, B2M, ACTB, ALAS1, GUSB, HPRT1, PBGD, PPIA, PUM1, RPL29, and TBP) for their reliability and stability as reference[] […] in the series of 72 hips (general population) w/ MRI changes c/w AVN (followed by Ito H, et al (1999)), 64% became symptomatic; - necrotic lesions greater than 2/3 of the wt[] Statistically significant differences between GANFH patients and either healthy controls or glucocorticoid-resistant patients (non-GANFH) were found for the T allele or TT[]

  • Amyloidosis

    RESULTS: We present design of NGS panel for 11 genes ( TTR , FGA , APOA1 , APOA2 , LYZ , GSN , CST3 , PRNP , APP , B2M , ITM2B ) connected to various forms of amyloidosis.[] […] natriuretic peptide ; Pcdh10 , protocadherin-10 ; PET , positron emission tomography ; SAP , serum amyloid P component ; TTR , transthyretin ; TUDCA , tauroursodeoxycholic acid ; wt[] There is a single orthologous gene in flies, CG30016 , for which classical amorphic and hypomorphic alleles, RNAi-targeting constructs, and alleles caused by insertional mutagenesis[]

  • Treponema Pallidum

    […] while the three middle regions demonstrated higher sensitivities and specificities for detecting IgG antibody, with 92.7% and 96.1% for FlaB1M ('B1M'), 91.6% and 94.8% for B2M[] […] per day (equivalent to 1 g per day wt/wt in humans) given orally once daily for two weeks, or erythromycin at 90 mg per day (equivalent to 2 g per day wt/wt in humans) given[] Four of these heterogeneous sites were found in both genomes but the frequency of alternative alleles differed.[]

  • Amegakaryocytic Thrombocytopenia

    RAD51, BUB1B, GALNT12, NSD2, HOXD13, NKX3-2, ALOX12B, CYLD, CTNNA3, FLG, NLRP1, FLT1, KDR, WNT10A, ZNF384, TNFAIP3, NCSTN, LYN, PSENEN, CARD8, HTR1A, PLCG2, GATA5, KDSR, B2M[] Stable expression of FLAG-HOXA11-WT or -DeltaH3 in K562 cells significantly impacts megakaryocytic differentiation.[] […] both abnormal alleles.[]