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28 Possible Causes for Amidophosphoribosyltransferase, Inhibitor

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  • Hereditary Angioedema

    We present the case of a patient with HAE-nC1INH who was successfully managed in the perioperative period with plasma derived C1-esterase inhibitor (pdC1INH).[ncbi.nlm.nih.gov] […] hydrolase Deficiency of alpha-amylase Deficiency of alpha-galactosidase Deficiency of alpha-glucosidase Deficiency of amidase Deficiency of amidinotransferase Deficiency of amidophosphoribosyltransferase[icd9data.com] KEYWORDS: Berinert ; C1 inhibitor; drug safety; hereditary angioedema; off label; pharmaco-epidemiological; registry[ncbi.nlm.nih.gov]

  • Angioedema

    OBJECTIVE: To describe 2 cases of angiotensin-converting enzyme inhibitor (ACEI)-induced angioedema treated with C1 esterase inhibitor (human) [Berinert].[ncbi.nlm.nih.gov] […] hydrolase Deficiency of alpha-amylase Deficiency of alpha-galactosidase Deficiency of alpha-glucosidase Deficiency of amidase Deficiency of amidinotransferase Deficiency of amidophosphoribosyltransferase[icd9data.com] ACE inhibitor–related angioedema.[doi.org]

  • Allopurinol

    The prototypical xanthine oxidase (XO) inhibitor allopurinol, has been the cornerstone of the clinical management of gout and conditions associated with hyperuricemia for[ncbi.nlm.nih.gov] These metabolites may act to inhibit de novo purine biosynthesis by inhibiting the enzyme, amidophosphoribosyltransferase .[drugbank.ca] Other Review Article Pharmacological Reviews March 2006, 58 (1) 87-114; DOI: Abstract The prototypical xanthine oxidase (XO) inhibitor allopurinol, has been the cornerstone[dx.doi.org]

  • Aromatic L-Amino Acid Decarboxylase Deficiency

    We now report one female patient who improved her motor and cognitive function after being prescribed a MAO-B inhibitor.[ncbi.nlm.nih.gov] […] hydrolase Deficiency of alpha-amylase Deficiency of alpha-galactosidase Deficiency of alpha-glucosidase Deficiency of amidase Deficiency of amidinotransferase Deficiency of amidophosphoribosyltransferase[icd9data.com] There may be differences in the mode of action, side-effect risk and effectiveness between different dopamine agonists and monoamine oxidase inhibitors currently used for[ncbi.nlm.nih.gov]

  • Mevalonate Kinase Deficiency

    Farnesyltransferase inhibitors (FTIs) act at the end of mevalonate pathway.[ncbi.nlm.nih.gov] […] hydrolase Deficiency of alpha-amylase Deficiency of alpha-galactosidase Deficiency of alpha-glucosidase Deficiency of amidase Deficiency of amidinotransferase Deficiency of amidophosphoribosyltransferase[icd9data.com] México - Estados Unidos The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.[pesquisa.bvsalud.org]

  • Mycobacterium Smegmatis

    These data reveal that a significant proportion of M. tuberculosis inhibitors are missed in library screening with M. smegmatis.[ncbi.nlm.nih.gov] .: #20218] Marker Gene (GenBank Direct submission) Mycobacterium smegmatis strain DSM 43756 amidophosphoribosyltransferase PurF (purF) gene, partial cds KF410464 687 1772[bacdive.dsmz.de] SIGNIFICANCE AND IMPACT OF THE STUDY: These results provided a possibility of combined application of rifampin together with tunicamycin or other WecA inhibitors, which could[ncbi.nlm.nih.gov]

  • Mercaptopurine

    Thus, ongoing clinical trials are testing mTOR inhibitors in combination with chemotherapy in B-ALL.[ncbi.nlm.nih.gov] Humans Pharmacological action Unknown Actions Inhibitor General Function Metal ion binding Specific Function Not Available Gene Name PPAT Uniprot ID Q06203 Uniprot Name Amidophosphoribosyltransferase[drugbank.ca] […] to a PARP inhibitor or cisplatin.[ncbi.nlm.nih.gov]

  • Guanabenz

    Proteasomal inhibitors, lactacystin, Cbz-leucine-leucine-leucinal, and N-acetyl-leucine-leucine-norleucinal, but not the lysosomal protease inhibitor leupeptin, were found[ncbi.nlm.nih.gov] PPAT 0.0006 2515 Amidophosphoribosyltransferase purF 0.0006 3714 Amidophosphoribosyltransferase purF 0.0006 422 Vitamin K-dependent protein C PROC 0.0006 537 ATP synthase[alpha.dmi.unict.it] Inhibitor 0.884 CYP450 2C19 inhibitor Non-inhibitor 0.9158 CYP450 3A4 inhibitor Non-inhibitor 0.9135 CYP450 inhibitory promiscuity Low CYP Inhibitory Promiscuity 0.8825 Ames[drugbank.ca]

  • Disorder of Purine Metabolism

    By decreasing the synthesis of uric acid using Enzyme inhibitor 3. By increasing oxidation of uric acid.[7med-pdf.com] The first committed step is the reaction of PRPP, glutamine and water to 5'-phosphoribosylamine (PRA), glutamate , and pyrophosphate - catalyzed by amidophosphoribosyltransferase[en.wikipedia.org] A more recent xanthine oxidase inhibitor is febuxostat. Febuxostat (Uloric) is a non-purine analog selective inhibitor of xanthine oxidase.[themedicalbiochemistrypage.org]

  • Hypoxanthine Guanine Phosphoribosyltransferase Partial Deficiency

    A more recent xanthine oxidase inhibitor is febuxostat. Febuxostat (Uloric) is a non-purine analog selective inhibitor of xanthine oxidase.[themedicalbiochemistrypage.org] 4.1 2 3 4 5 6 5.1 2 3 4 99 6.1-3 4 5-6 Metabolism : amino acid metabolism · nucleotide enzymes Purine metabolism Anabolism R5P - IMP : Ribose-phosphate diphosphokinase · Amidophosphoribosyltransferase[dictionnaire.sensagent.leparisien.fr] "Establishment of Correlation between In-Silico &In-Vitro Test Analysis against Leishmania HGPRT to inhibitors".[ipfs.io]

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