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1,517 Possible Causes for Antibody, Histone

Did you mean: antimony, Histone

  • Drug-induced Lupus Erythematosus

    In those patients with antihistone antibodies (DILE versus DANA patients), there were no differences in the mean antibody titers.[ncbi.nlm.nih.gov] Furthermore, Anti-Histone antibodies can also be positive in drug induced lupus. Anti-Histone antibodies are positive in up to 95% of patients with drug induced lupus.[en.wikipedia.org] […] characterized by typical lupus-like symptoms including skin signs, usually mild systemic involvement and a typical laboratory profile with positive antinuclear and anti-histone[ncbi.nlm.nih.gov]

  • Viral Lower Respiratory Infection

    Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication.[ijcancerprevention.com] A swab is dipped in the urine and then placed on a nitrocellulose membrane that contains rabbit antibodies against S. pneumoniae.[mja.com.au] However, over time, the virus can change into different forms, which means the body may not have the right antibodies to fight it again.[europeanlung.org]

  • Drug-induced Fever

    Thus they are called anti-histone antibodies. Anti-histone antibodies may be seen in both systemic lupus erythematosus and drug-induced lupus.[clinicaladvisor.com] The antihistone antibodies in DIL primarily form against a complex of the histone dimer H2A-H2B, which is in contrast to idiopathic SLE in which complexes are formed against[uspharmacist.com] Anti-isoniazid antibody could not be assessed due to nonavailability of this antibody detection facility.[lungindia.com]

  • Dementia

    Fischer , Histone Deacetylases as Therapeutic Targets in Neurodegenerative Diseases , Medical Epigenetics , 10.1016/B978-0-12-803239-8.00003-X , (33-45) , (2016) .[doi.org] Pittock SJ, Kryzer TJ, Lennon VA: Paraneoplastic antibodies coexist and predict cancer, not neurological syndrome . Ann Neurol 2004, 56: 715–719.[doi.org] Read More Computer-designed antibodies target toxins associated with Alzheimer’s disease 22 Jun 2017 Researchers at the University of Cambridge have designed antibodies that[cam.ac.uk]

  • Osteoporosis

    However, unlike PTH, sclerostin antibody also decreases bone resorption (anti-catabolic). Although, the U.S.[ncbi.nlm.nih.gov] Histone modifications can regulate gene expression by influencing interactions between DNA and histones, for example by acetylation and methylation of conserved lysine residues[doi.org] Denosumab is a fully human monoclonal antibody to RANK Ligand that is administered as a 60-mg subcutaneous injection every 6 months.[ncbi.nlm.nih.gov]

  • Adrenal Insufficiency

    Tõnis Org, Ana Rebane, Kai Kisand, Martti Laan, Uku Haljasorg, Reidar Andreson and Pärt Peterson , AIRE activated tissue specific genes have histone modifications associated[doi.org] Since serum aldosterone was below the reference range, more importantly, assessments for both antiadrenal antibodies and anti-21-hydroxylase antibodies were positive, she[ncbi.nlm.nih.gov] […] was very difficult to confirm that the sarcomatoid carcinomas were derived from the cortex of the adrenal glands, but careful morphological observation and the panel of antibodies[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    Like other antibodies involved in lupus that are directed against self (auto-antibodies), antiphospholipid antibodies can come and go or increase and decrease.[hopkinslupus.org] Systemic lupus erythematosus (SLE) is an autoimmune disease in which patients develop autoantibodies to DNA, histones, and often to neutrophil proteins.[ncbi.nlm.nih.gov] This review provides data that show that such autoantibodies cause the renal lesions of systemic lupus erythematosus, and it emphasizes the importance of histones, histone[doi.org]

  • Herpes Simplex Virus 2 Infection

    Unlike trichostatin A that promotes HSV-2 infection and histone modifications, myriocin treatment did not alter histone modifications.[ncbi.nlm.nih.gov] The presence of complement in combination with HSV-1- or HSV-2-specific antibodies more or less abolished HSV-2 infection of DCs.[ncbi.nlm.nih.gov] In 49 out of the 100 HIV seropositives, IgG2 antibodies against HSV-2 were detected.[ncbi.nlm.nih.gov]

  • Microscopic Polyangiitis

    Anti-neutrophil cytoplasmic antibodies (ANCA) appear to play an important role in the pathogenesis of ANCA-associated vasculitis (AAV).[ncbi.nlm.nih.gov] Biopsy revealed citrullinated histone H3 (citH3)-positive neutrophils adherent to the temporal artery endothelium.[ncbi.nlm.nih.gov] Stored nerve samples from 17 patients with microscopic polyangiitis (MPA) were immunohistochemically analyzed using antibodies for citrullinated histone H3 (citH3) and various[ncbi.nlm.nih.gov]

  • Tuberculosis

    Comparative gene expression profiling revealed that many of the Mtb genes involved in protein synthesis, ESX-3/secretion, iron metabolism and histone-like proteins were up-regulated[ncbi.nlm.nih.gov] , and none had anti-PR3 antibodies.[ncbi.nlm.nih.gov] METHODS: BMMs were isolated and co-cultured with CD4 T helper 1 cells (Th1 cells), pretreated with anti-IFN-γ antibody.[ncbi.nlm.nih.gov]

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