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  • Spinal Metastasis

    Abstract The first case of a gallbaldder carcinoma with metastasis to dura and epidural space causing myelopathy is described.[] All patients had at least 1 level associated with epidural encroachment related to metastasis.[] Augmented prostaglandin E2 generation resulting from increased activities of cytosolic and secretory phospholipase A2 and induction of cyclooxygenase-2 in interleukin-1 beta-stimulated[] Abstract Preoperative direct percutaneous embolization has been very rarely used in hypervascular metastatic spinal tumors to decrease blood loss during the surgery.[] INTRODUCTION: Symptomatic metastatic spinal disease is on the increase.[] Using image-guidance, the pedicle is cannulated and the vertebral body injected with cement; the process is exothermic and thus antineoplastic locally and is typically an[] High doses of radiation are associated with major toxicity, therefore is preferred the administration of low doses.[] The results show that the proposed approach correctly detects all the spinal metastatic lesions while producing only 0.40 FPs per case.[] […] mass in L2-3 with infiltration of the cauda equina; the lesion measured 13 mm craniocaudally and 11 mm anteroposteriorly, and thus occupied the majority of the intrathecal space[] CT and myelography were very useful until the introduction of MRI, one of the most important diagnostic modalities when it comes to spinal metastasis.[]

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  • Interleukin-2

    Description The International Space Station provides a modern platform to study physiology and molecular changes in space.[] The authors report the case of a patient with a metastatic renal cell carcinoma who had an asymptomatic intra-epidural metastasis in the thoracic spine, which became symptomatic[] Effects of interleukin-2 and interleukin-2-activated cells on in vitro myelopoiesis.[] It is difficult to differentiate angiosarcoma from epithelioid hemangioendothelioma based on the image findings and pathological findings of percutaneous liver biopsy.[] The survivor whose condition 23 months following introduction of IL-2 therapy is very good, demonstrates that IL-2 offers some chance to these hopeless patients.[] System Agents Anti-HIV Agents Anti-Retroviral Agents Antineoplastic Agents, Phytogenic[] Ten patients who had received low-dose IL-2 were retrospectively identified.[] Due to the toxicities associated with systemic IL-2, an aerosolized delivery approach has been developed, which enables localized delivery and a higher local immune cell activation[] Introduction IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes.[] Using a human OS mouse model, we demonstrated the efficacy of this approach.[]

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  • Aspirin

    In the enclosed spinal canal, even a small space-occupying lesion may be rapidly symptomatic.[] OBJECTIVE: We present a case report of a patient who developed an epidural hematoma following an interlaminar epidural steroid injection with no risk factors aside from old[] Rho prevents apoptosis through Bcl-2 expression: implications for interleukin-2 receptor signal transduction . Eur J Immunol. 1997 ;27: 2793 - 2799 .[] Abstract Dual antiplatelet therapy including aspirin and a P2Y12 ADP receptor antagonist is given after percutaneous coronary intervention to avoid catastrophic complication[] INTRODUCTION: The antiplatelet effect of low-dose aspirin in patients with type 2 diabetes (T2DM) without cardiovascular disease (CVD) has not been thoroughly explored.[] There are also a number of non-COX–related pathways that may underlie aspirin's antineoplastic effects.[] Researchers have documented that low-dose aspirin, taken daily after the first trimester, can decrease the development of preeclampsia and reduce the incidence of preterm[] These studies used radiolabeled 3H or 14C aspirin, the only approach used to date for the detection of proteins acetylated by aspirin.[] OBJECTIVE: Spinal epidural hematoma is a rare, but potentially devastating, consequence of accessing the epidural space for anesthesia or interventional pain procedures.[] Nitric oxide amplifies interleukin 1-induced cyclooxygenase-2 expression in rat mesangial cells. J. Clin. Invest. 97 : 2051 –2056. Salvemini, D., T.P. Misko, J.L.[]

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  • Meningitis

    Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord and nerve roots[] Epidural inflammatory… Read More What are the recently reported neurological features of IgG4-related disease?[] 2, and interleukin 6. 114 Moreover, administration of OKT3 antibodies increases systemic cytokine levels, which may contribute to the inflammatory response. 144 It has been[] The principal intervention for reducing elevated intracranial pressure is percutaneous lumbar drainage [ 21 , 22 ] (AII).[] Abstract Meningitis caused by Haemophilus influenzae type b (Hib) was eliminated in Oman after the introduction of Hib vaccine in 2001.[] […] cents per dose.[] In addition to the unusual biological results (normoglycorachia and bacterial morphology after Gram staining), we present the biological diagnostic approach (molecular, biochemical[] […] persistent pressure elevation 25 cm of CSF and symptoms, repeat lumbar puncture daily until the CSF pressure and symptoms have been stabilized for 2 days and consider temporary percutaneous[] The history of community-acquired bacterial meningitis arguably represents the best example of the salutary effect of the introduction of antimicrobial agents.[] A multidisciplinary approach, including intensive care, is often required in the treatment of these infections.[]

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  • Myocardial Infarction

    Figure 1 Cholesterol transport within cells and extracellular space.[] Favorites PDF Get Content & Permissions Open Epidural chloroma and spinal cord compression Koh, Hyun Jung; Baek, Jungwon; Lee, Min Soo; More Chinese Medical Journal. 132(7[] Soluble serum interleukin-2 receptor, interleukin-6 and interleukin-1a in patients with endometriosis and in controls. Arch Gynecol Obstet . 1994 ; 255 :107–112.[] Management of patients after primary percutaneous coronary intervention for myocardial infarction Practice Clinical updates BMJ 2017 ; 358 doi: (Published 20 July 2017) Cite[] OBJECTIVE: Introduction: The number of elderly people in society is increasing.[] […] and possibly other anticancer drugs may alter biomarker levels. 815 Antineoplastic agents can induce changes in the arterial wall, 813 and modulators of inflammation may[] There was low inter-observer variability in the classification of wall motion and the response to low-dose dobutamine (agreement 96%).[] Case Report Lateral Left Ventricular Wall Rupture Following Acute Myocardial Infarction: Pathophysiological Interpretation by Multimodality Imaging Approach Corresponding[] Indeed, significantly increased levels of proinflammatory cytokines such as interleukin 1β, tumor necrosis factor-α, interleukin 6, as well as other proinflammatory active[] Introduction: miRNAs contribute to a variety of essential biological processes including development, proliferation, differentiation, and apoptosis.[]

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  • Pneumonia

    She underwent surgical lung biopsy that revealed inflammatory infiltrate, macrophage desquamation, fibroblasts proliferation and fibrin deposition in the alveolar spaces,[] 2 (IL‐2) and tumour necrosis factor‐α (TNF‐α) ( Krebs 2014 ).[] To confirm the diagnosis, we performed bronchoscopy and percutaneous lung biopsy; pathology was consistent with AFOP.[] We cannot determine to what extent the observed changes are due to the introduction of vaccination or to other factors.[] PubMed Google Scholar Blum RH, Carter SK, Agre K: A clinical review of bleomycin - a new antineoplastic agent.[] Different doses (low, medium, high). 2. Duration of treatment.[] This review summarizes the recent advances in the field of therapy and novel approaches.[] For this test, a fluid sample is taken from the pleural space (a thin space between two layers of tissue that line the lungs and chest cavity).[] Hallmarks of pathological findings are characterized by the presence of intra-alveolar fibrin in the form of fibrin "balls" within the alveolar spaces and organizing pneumonia[] However, as the efficacy of minimally invasive interventional procedures has been well established, image-guided small percutaneous drainage tubes have been considered as[]

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  • Cauda Equina Syndrome

    Caudal migration of the bullet within the spinal subarachnoid space leads to the appearance of cauda equina syndrome.[] His pain had greatly intensified 1 day after spinal epidural steroid injection.[] KEYWORDS: Cauda equina syndrome; Endoscope; Lumbar disc herniation; Percutaneous discectomy[] INTRODUCTION: Cauda equina syndrome (CES) is a condition with significant implications and medico-legal profile.[] Publication type, MeSH terms, Substance Publication type Case Reports MeSH terms Aged Antineoplastic Combined Chemotherapy Protocols/therapeutic use Biomarkers, Tumor/analysis[] Adjuvant medication such as low dose antidepressants, anticonvulsants, and neurontin often help the person.[] Surgical outcome immediately and 3, 6, 12, 36 months after the surgery were compared to evaluate the effectiveness two different approaches.[] INTRODUCTION: Patients with cauda equina syndrome (CES) are frequently referred late when neurological damage cannot be reversed.[] BACKGROUND CONTEXT: Percutaneous intradiscal therapies are gaining popularity as a regenerative treatment option for spinal disc degeneration.[] INTRODUCTION: Correlation between magnetic resonance imaging (MRI) and clinical features in cauda equina syndrome (CES) is unknown; nor is known whether there are differences[]

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  • Essential Thrombocythemia

    Orbital computed tomography revealed a relatively well-defined homogenous mass-like lesion in the left subconjunctival and intraconal space.[] Postoperative spinal epidural hematoma is an uncommon, but well-known, complication after spinal surgery.[] […] effect of platelet- inhibiting factors (transforming growth factor [TGF] beta) 7. mutation Janus kinase 2 (JAK2) V617F • 50% in ET patient • Turn thrombopoietin receptor[] Percutaneous aspiration thrombectomy was performed with no residual stenosis. The patient was discharged on antiplatelet agents, aspirin, and clopidogrel.[] INTRODUCTION: A high platelet count, or thrombocytosis, is either a reactive process or a result of a myeloproliferative disorder.[] Publication type, MeSH terms, Substances Publication type Case Reports MeSH terms Antineoplastic Agents/therapeutic use Benzamides/therapeutic use Female Humans Imatinib Mesylate[] We assessed the benefit/risk of low-dose aspirin in 433 patients with low-risk essential thrombocythemia (271 with a CALR mutation, 162 with a JAK2(V617F) mutation) who were[] Several unmet needs remain, above all, the lack of a curative approach that might overcome the still burdensome morbidity and mortality of these hematologic neoplasms, as[] The author apologizes to many eminent colleagues whose work in the field can not be cited because of space limitations.[] Introduction:: In patients with essential thrombocythemia (ET), the vascular complications contribute to morbidity and mortality.[]

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  • Idiopathic Pulmonary Fibrosis

    […] article we review the profound alterations in lung mechanics (reduced lung compliance and lung volumes), pulmonary gas exchange (reduced diffusing capacity, increased dead space[] Idiopathic pulmonary fibrosis is etiologically heterogeneous and biologically dynamic, and sequence changes in MUC5B , transcriptional signatures in the fibrotic lung, 2 ,[] Therefore, findings on bronchoscopic or percutaneous lung biopsy are difficult to interpret.[] Moreover, FVC was improved 6 months after nintedanib introduction in 12 out of 24 patients with the complete set of the relevant data.[] Bleomycin is a glycopeptide produced by Streptococcus verticillus that is used in human medicine as an antineoplastic chemotherapeutic and is known to induce pulmonary fibrosis[] Abstract We report on a 74-year-old man with an acute exacerbation of idiopathic pulmonary fibrosis (IPF) who was successfully treated with prolonged low-dose methylprednisolone[] Here we highlight the strengths and limitations of the multidisciplinary approach to IPF diagnosis through MDT discussion of two patient cases. Copyright ERS 2015.[] Lung ultrasound (LUS) as a noninvasive, non-radiating examination is very sensitive to detect subtle changes in the subpleural space.[] Low-dose nebulized morphine does not improve exercise in interstitial lung disease . Am J Respir Crit Care Med 1995 ; 152: 1940 – 1945 .[] The patient underwent a single lung transplantation by means of a normothermic ex vivo lung perfusion (EVLP) approach according to the Toronto model.[]

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  • Subdural Hematoma

    OBJECTIVE: To compare the outcome after surgery for chronic subdural hematoma when the drain is placed in subdural space or subgaleal space.[] […] a recognized dural puncture occurred during epidural catheter placement.[] IMA J Math Appl Med. 2001;18(2):159–92. View Article Google Scholar Moore KW, O’Garra A, deWaal MR, et al. Interleukin-10. Annu Rev Immunol. 1993;11:165–90.[] Few patients of DASH after mild traumatic brain injury associated with percutaneous coronary intervention (PCI) have been published.[] This study, solely focused on the Brazilian population, is the first of its kind in the English literature, and it could serve as a useful introduction to a more complex,[] BACKGROUND: The aim of this international survey was to investigate the current management of patients undergoing surgery for chronic subdural hematoma (cSDH) treated with low-dose[] BACKGROUND: Calcified chronic subdural hematoma (CCSDH) is a rare disease for which no standard approach to treatment has been established.[] SPINAL TRATAMENTUL OSTEO-MIELITEI VERTEBRALE TRATAMENTUL MALFORMATIILOR SPINALE Interventii spinale minim invazive VERTEBROPLASTIE KIPHOPLASTIE STENTOPLASTIE FIXARE SPINALA PERCUTAN[] INTRODUCTION: Traumatic spinal subdural hematoma involving the retroclival region and upper cervical spine is a rare pathology.[] The blood from a ruptured aneurysm may dissect through the brain parenchyma or subarachnoid space into the subdural space.[]

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