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5,243 Possible Causes for Aryl, Hydrocarbon, Nuclear, Receptor, Translocator

Did you mean: Aryl, hydrocarbons, Nuclear, Receptor, Translocator

  • Acromegaly

    The gene aryl hydrocarbon receptor interacting protein, AIP (11q13.3), has been identified as a major susceptibility factor, particularly in cases of familial acromegaly or[orpha.net] […] to investigate the effect of hyperprolactinemia and high levels of insulin-like growth factor-I (IGF-I) on bone resorption and their relation with receptor activator of nuclear[ncbi.nlm.nih.gov] Somatostatin receptor ligands (SRLs) and pegvisomant (PegV) are used for treatment of acromegaly and there is evidence that both drugs may exert direct effects on peripheral[ncbi.nlm.nih.gov] Clarke JF, Young PW, Yonezawa K, Kasuga M, Holman GD, 1994 Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor[doi.org] Daly AF and Beckers A (2015) Familial isolated pituitary adenomas (FIPA) and mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene.[els.net]

  • Urinary Tract Infection

    Using X-ray structure-guided methods, virtual screening, and multiplex ELISA arrays, we rationally designed aryl galactosides and N -acetylgalactosaminosides that inhibit[ncbi.nlm.nih.gov] […] pathways in prostate cancer Jason Kubinak – Interaction of primary antibody deficiency and inflammation caused by host-microbiome dysbiosis Narendra Singh – Role of aryl hydrocarbon[pathmicro.med.sc.edu] Author information 1 Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China. 2 Department of Nuclear Medicine[ncbi.nlm.nih.gov] Armant MA, Fenton MJ (2002) Toll like receptors: a family of pattern recognition receptors in mammals. Genome Biol 3(8):3011.1–3011.6 CrossRef Google Scholar 8.[doi.org] We hypothesised that in hospitalised patients, UPEC strains might translocate from the gut to the blood stream and that this could be due to the presence of virulence genes[ncbi.nlm.nih.gov]

  • Retinoid

    Those two drugs act asimmunomodulators and potential activators of aryl hydrocarbon receptor.[tdx.cat] Basic Hydrocarbon The hydrocarbon ( 4 ), also known as axerophthene, should be designated deoxyretinol (see note).[sbcs.qmul.ac.uk] Abstract The promiscuous protein retinoid X receptor (RXR) displays essential allosteric regulation of several members in the nuclear hormone receptor superfamily via heterodimerization[ncbi.nlm.nih.gov] Karyotype analysis and RNA-Seq revealed the presence of a novel t(4;15)(q31;q22) reciprocal translocation involving the TMEM154 and RASGRF1 genes.[ncbi.nlm.nih.gov] […] significantly improved by access to a key C-benzyl-glucuronide intermediate through employment of a Suzuki coupling reaction between an exoanomeric methylene sugar and an aryl[ncbi.nlm.nih.gov]

  • LIG4 Syndrome

    […] reveal the mechanism by which C1P is transported from its Alcohols as Latent Coupling Fragments for Metallaphotoredox Catalysis: sp 3 –sp 2 Cross-Coupling of Oxalates with Aryl[clippingpathtoindia.com] Vaccinia Intercalating polycyclic aromatic hydrocarbon-DNA adducts poison DNA religation by Vaccinia topoisomerase and act as roadblocks to digestion by exonuclease III.[brenda-enzymes.org] Ligase IV might facilitate efficient nuclear localization of XRCC4 by increasing its nuclear retention and/or by allowing its nuclear translocation.[docksci.com] NHEJ is also used to repair the DNA double-strand break intermediates that occur in the production of T and B lymphocyte receptors.[en.wikipedia.org] Chromosome 7/14 translocations are also common.[orpha.net]

  • Malignant Neoplasm

    Paul Gleeson , Synthesis and evaluation of the NSCLC anti-cancer activity and physical properties of 4-aryl- N -phenylpyrimidin-2-amines , Bioorganic & Medicinal Chemistry[dx.doi.org] Of major concern are: outdoor air pollution by carbon particles associated with polycyclic aromatic hydrocarbons; indoor air pollution by environmental tobacco smoke, formaldehyde[ncbi.nlm.nih.gov] Nuclear cytomegaly was present focally enhancing the atypical appearance of the tumor cell population in 17 cases. Mitoses were sparse ([ncbi.nlm.nih.gov] The receptor status determines if the cancer calls are receptive to certain hormones. This status helps decide which treatment methods will be best.[knowcancer.com] Most solid tumors have dozens of translocations; however, as with point mutations, the majority of translocations appear to be passengers rather than drivers.[doi.org]

  • Atypical Chronic Myeloid Leukemia

    Gentil M, Hugues P, Desterke C, Telliam G, et al « Aryl hydrocarbon receptor (AHR) is a novel druggable pathway controlling malignant progenitor proliferation in chronic myeloid[ca.wikipedia.org] 5;10)(q33;q22) in a 49-year-old man with atypical chronic myeloid leukemia (a-CML) and history of occupational exposure to petroleum products including benzene and other hydrocarbons[ncbi.nlm.nih.gov] Factors/genetics Transcription Factors/metabolism Substances Carrier Proteins Histone Chaperones Nuclear Proteins SET protein, human SETBP1 protein, human Transcription Factors[ncbi.nlm.nih.gov] These findings indicate transformation to have occurred in a hemopoietic stem cell with the capacity for antigen receptor gene rearrangement.[ncbi.nlm.nih.gov] We report a case of BCR-ABL-negative atypical chronic myeloid leukemia (CML) with translocation t(4;22) (q12;q11.2) juxtaposing the breakpoint cluster region (BCR) and platelet-derived[ncbi.nlm.nih.gov]

  • Chenodeoxycholic Acid

    […] semicarbazones EP0442816A1 ( de ) 1991-08-21 Alpha-Hydroxylsäuren, Verfahren zu ihrer Herstellung und Verwendung BE858897A ( fr ) 1978-01-16 Esters phtalidyliques d'acides aryl-alcanoiques[google.co.ug] Secondary alcohols Cyclic alcohols and derivatives Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon[foodb.ca] CDCA derivatives demonstrated various apoptosis hallmarks, such as mitochondrial changes, activation of caspase, DNA fragmentation, and nuclear condensation.[ncbi.nlm.nih.gov] Abstract Farnesoid X receptor (FXR), the receptor for bile acids, including chenodeoxycholic acid (CDCA), is a member of the nuclear receptor superfamily, which also includes[ncbi.nlm.nih.gov] These results provide evidence for a nuclear bile acid signaling pathway that may regulate cholesterol homeostasis.[ncbi.nlm.nih.gov]

  • Synovial Sarcoma

    Wang S, Hankinson O (2002) Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex[doi.org] CONCLUSIONS: In this series nuclear phospho-Rb and nuclear β-catenin expression were negative prognostic factors.[ncbi.nlm.nih.gov] KEYWORDS: NY-ESO-1; adoptive T-cell therapy; chimeric antigen receptor; engineered T cell; synovial sarcoma; tumor-infiltrating lymphocytes Publication type, MeSH terms, Substances[ncbi.nlm.nih.gov] Some of these factors such as grade and histology, specific translocations (SS18-SSX1 vs.[ncbi.nlm.nih.gov] Histopathological examination showed spindled morphology of tumor cells with hypercellularity and nuclear atypia.[ncbi.nlm.nih.gov]

  • Influenza

    Access to the fourth and fifth series of compounds was achieved by click chemistry, introducing single alkyl/aryl chains directly or through a tetraethylene glycol linker[ncbi.nlm.nih.gov] To insure efficient transport across the nuclear membrane, these viruses use nuclear import and export signals exposed on the vRNPs.[ncbi.nlm.nih.gov] Electron density of the receptors.[doi.org] Surprisingly, the majority of viruses experience their initial acidification in the perinuclear region immediately following the dynein-directed rapid translocation step.[doi.org] Science and Technology Genetics Genomics and Human Genetics Immunology Law and Social Science Linguistics Marine Science Materials Research Medicine Microbiology Neuroscience Nuclear[doi.org]

    Missing: Hydrocarbon
  • Translocation Renal Cell Carcinoma

    […] for up to 50% of cases. [14] Occupational exposure to some chemicals such as asbestos, cadmium, lead, chlorinated solvents, petrochemicals and PAH ( polycyclic aromatic hydrocarbon[en.wikipedia.org] nuclear immunoreactivity for TFE3.[ncbi.nlm.nih.gov] […] feasibility and opportunity of treating such a patient with multiple line of tyrosine kinase inhibitor (TKI) targeting vascular endothelial and platelet-derived growth factor receptors[ncbi.nlm.nih.gov] In recent years, at least 6 different Xp11.2 translocation RCCs have been identified and characterized at the molecular level.[ncbi.nlm.nih.gov] Immunohistochemically, the tumor cells marked with TFE3, focally marked with smooth muscle actin, HMB-45, CD68, progesterone receptor (PR) and CD10 but did not mark with epithelial[ncbi.nlm.nih.gov]

    Missing: Aryl