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130 Possible Causes for Assays,, Micronucleus

  • Senna

    From the results, the in vitro clastogenic activity of the senna extract could not be confirmed in the mouse micronucleus assay.[ncbi.nlm.nih.gov] The extract was assayed for the in vitro anticancer activity using Jurkat T cells, antioxidant activity using DPPH assay and antibacterial activity by bioautographic method[ncbi.nlm.nih.gov] The antioxidant properties were evaluated using a DPPH free radical scavenging assay and by examining the extract's inhibition of AAPH-induced lipid peroxidation in human[ncbi.nlm.nih.gov]

  • Bicarbonate

    METHODS: The cytokinesis-block micronucleus (MN) assay was performed on peripheral blood lymphocytes to evaluate genetic damage.[ncbi.nlm.nih.gov] Cell viability and apoptosis of human peritoneal mesothelial cells (HPMCs) were examined by water-soluble tetrazolium salt-1 and TUNEL assays, respectively.[ncbi.nlm.nih.gov] METHODS: The cytokinesis-block micronucleus (MN) assay was performed on peripheral blood lymphocytes to evaluate genetic damage.[ncbi.nlm.nih.gov]

  • African Trypanosomiasis

    No significant genotoxicity was observed at the chromosome level (micronucleus assay).[ncbi.nlm.nih.gov] The diagnosis was confirmed when the PCR assay demonstrated the presence of parasite DNA in CSF and blood.[ncbi.nlm.nih.gov] Antigens were subjected to Luminex multiplex assays using sera from HAT and VL patients to assess the antigens' immunodiagnostic potential.[ncbi.nlm.nih.gov]

  • Clofibrate

    The repeated-dose liver micronucleus (MN) assay is a newly established in vivo genotoxicity test for evaluation of liver carcinogens.[ncbi.nlm.nih.gov] The assay involves extraction of the compounds into chloroform-isoamyl alcohol (99:1, v/v) from plasma acidified with sulfuric acid.[ncbi.nlm.nih.gov] A nuclear run-off assay and RT-PCR measurements of L-FABP mRNA revealed that clofibrate increased the L-FABP gene transcription rate.[ncbi.nlm.nih.gov]

  • Chromosome Aberration

    Peripheral blood samples were collected from three victims exposed to (60)Co 10 days after the accident and were used for the chromosome aberration and micronucleus assays[ncbi.nlm.nih.gov] Comet assay were always at higher doses than in the cytogenetic test.[ncbi.nlm.nih.gov] Micronuclei were detected using the cytokinesis block micronucleus assay.[ncbi.nlm.nih.gov]

  • Chlortetracycline

    The lowest concentration of chlortetracycline slightly augmented the frequency of micronucleus (MN), chomosomal aberration (CA), and sister chomatid exchange (SCE) in the[ncbi.nlm.nih.gov] […] and triple stain assays.[ncbi.nlm.nih.gov] Capacitation and the acrosome reaction were monitored by a chlortetracycline (CTC) fluorescence assay. Four distinct CTC patterns were observed on the sperm head.[ncbi.nlm.nih.gov]

  • Permethrin

    Genotoxicity was evaluated using the cytokinesis-block micronucleus cytome (CBMN cyt) assay by measuring the frequency of micronuclei (MN), nuclear division index (NDI), formation[ncbi.nlm.nih.gov] Ex vivo assays showed no surviving lice after a 1-hour contact with malathion while most lice died after a 1-hour exposure to permethrin and piperonyl butoxide (85.7%, 95%[ncbi.nlm.nih.gov] […] commercial parental bulk form of permethrin (BP) on human peripheral erythrocyte/lymphocyte by erythrocyte morphology analysis, cell viability assay, and cytokinesis-block micronucleus[ncbi.nlm.nih.gov]

  • Thiabendazole

    In the present study, the genotoxic potential of thiabendazole have been evaluated, by micronucleus assay in freshly isolated human peripheral lymphocytes.[ncbi.nlm.nih.gov] Mutagenesis 13(2):193–198 PubMed CrossRef Google Scholar Fenech M (2000) The in vitro micronucleus technique.[link.springer.com] TBZ at 50-100 microg/ml with UVA-irradiation significantly induced micronuclei in WTK1 cells in the in vitro cytochalasin-B micronucleus assay.[ncbi.nlm.nih.gov]

  • Dimethyl Sulfoxide

    […] of DNA damage, A549 cells were exposed to toner-powder suspensions and to their DMSO extracts, and then subjected to the comet assay and to the in-vitro cytokinesis block micronucleus[ncbi.nlm.nih.gov] Therefore, using DMSO in invitro assays might result in misinterpretation of actual efficacy of drugs.[ncbi.nlm.nih.gov] […] to assess both the induction of DNA strand-breaks as identifiable by the alkaline comet assay and the persistence of chromosomal damages (micronuclei) as analyzed by the micronucleus[ncbi.nlm.nih.gov]

  • Onion

    In addition, we measured the frequency of micronuclei (MN) and DNA damage following treatment with BLM using a cytokinesis-blocked micronucleus assay and a single cell gel[ncbi.nlm.nih.gov] Based on immunofluorescent staining assay, western blot assay, and RNA knockdown data, we found that 8-CEPQ did not cause apoptotic cell death.[ncbi.nlm.nih.gov] Fasting blood samples were collected at initial, 2nd, 6th, 8th, 10th week for estimating various biochemical assays, as well as anthropometric indices.[ncbi.nlm.nih.gov]

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