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390 Possible Causes for B, Factor, Properdin

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  • Dirofilaria Immitis

    We have developed a single-tube, real-time PCR with a high-resolution melting (HRM) analysis assay for detection and identification of B. malayi, B. pahangi, and D. immitis[ncbi.nlm.nih.gov] […] the presence of diethylcarbamazine whereas the complement-fixing activity of microfilarial products was little affected by diethylcarbamazine; (2) complement proteins C3, properdin[ncbi.nlm.nih.gov] Positivity to mixed agents was not found to be a risk factor for disease.[ncbi.nlm.nih.gov]

  • Atypical Hemolytic Uremic Syndrome

    To date, influenza B has not been reported to trigger aHUS. A 6-month-old boy presented with hemolytic uremic syndrome triggered by influenza B infection.[ncbi.nlm.nih.gov] The same approach was used to model in vitro a potential aHUS treatment approach based on blocking the AP effector properdin (complement factor P; CFP) with an anti-properdin[ncbi.nlm.nih.gov] The subgroup of aHUS designated as DEAP (DEficiency of CFHR Proteins and CFH Autoantibody Positive)-HUS because of autoantibody to complement factor H (CFH) and CFH-related[ncbi.nlm.nih.gov]

  • Epilepsy

    Results Four patients (22.2%) were assigned to group A, 13 (72.2%) were assigned to group B, and 1 patient was assigned to group C (5.6%).[ncbi.nlm.nih.gov] Concentrations of 10 complement analytes (C1q, C3, C4, factor B [FB], terminal complement complex [TCC], iC3b, factor H [FH], Clusterin [Clu], Properdin, C1 Inhibitor [C1Inh[ncbi.nlm.nih.gov] Interpersonal factors explained more variation in depression levels in patients with PNES than those with epilepsy, for whom illness related factors were more influential,[ncbi.nlm.nih.gov]

  • Ovariectomy

    However, mice lacking RANKL in B lymphocytes were partially protected from the bone loss caused by ovariectomy.[ncbi.nlm.nih.gov] Results established upregulation of macrophage-associated (Cd45, Iba1, Cd68, Cd11b, Cd18, Fcgr1a, Fcgr2b) and complement (C3, factor B, properdin) genes in response to ovariectomy[ncbi.nlm.nih.gov] […] ovariectomy and ERT on serum leptin levels and anthropometric measurements as well as interaction among leptin, sex hormone binding globulin (SHBG), and insulin like growth factor-I[ncbi.nlm.nih.gov]

  • Lupus Nephritis

    Areas covered: This review provides an update regarding targeting B cells in LN.[ncbi.nlm.nih.gov] Serial sera samples were analyzed, and autoantibodies to complement alternative pathway proteins (Factor I, Factor B, C3 and Properdin) were found.[ncbi.nlm.nih.gov] MSCs suppressed systemic and intrarenal activation of C5, increased the plasma levels of factor H (FH), and ameliorated renal disease in lupus mice.[ncbi.nlm.nih.gov]

  • Pneumococcal Pneumonia

    […] pneumonia and influenza B infection in these facilities.[ncbi.nlm.nih.gov] Serum complement studies revealed decreased levels of C4, properdin, and C3.[ncbi.nlm.nih.gov] This retrospective study assessed these factors in hospitalized patients suffering from pneumococcal pneumonia from 2002 to 2015.[ncbi.nlm.nih.gov]

  • Membranoproliferative Glomerulonephritis

    PRES as a complication during the treatment of MPGN secondary to hepatitis B has, to our knowledge, never been reported previously in the literature.[ncbi.nlm.nih.gov] NFt stabilizes the alternative pathway properdin-dependent C3/C5 convertase (C3Bb2,Bb,P) and leads to C3 activation and consumption.[emedicine.medscape.com] Factor H autoantibodies are found in 10% of aHUS patients.[ncbi.nlm.nih.gov]

  • Gamma Globulin

    A 49-yr-old man with chronic hepatitis B manifested hypergammaglobulinemia, lymphadenopathy, and a high serum interleukin-6 level following treatment with recombinant human[ncbi.nlm.nih.gov] […] to belong to the γ 1A (β 2A ) globulins of similar size, and an ever increasing number of antibodies and biologically active substances such as the rheumatoid factor and properdin[annals.org] The VII:C level was 2%, and 4 Bethesda units of factor VIII inhibitor were detected.[ncbi.nlm.nih.gov]

  • Cefotaxime

    The authors describe a case of relapse of Neisseria meningitidis serogroup B meningitis in a 21-y-old male, 48 h after a 5-day treatment with cefotaxime 215 mg/kg per day.[ncbi.nlm.nih.gov] Risk factors and antibiograms may improve the selection of appropriate therapy for CTXNS-En bacteremia.[ncbi.nlm.nih.gov] Group B Streptococcus is a primary source of pneumonia, which is a leading cause of death worldwide.[ncbi.nlm.nih.gov]

  • Necrotizing Ulcerative Gingivitis

    Specific alleles at complement factors C3 and C4, and properdin factor B (Bf) loci were determined indirectly by high voltage agarose gel electrophoresis in 58 subjects with[ncbi.nlm.nih.gov] However, with regard to Synergistetes cluster B bacteria, there were no differences between NUG and gingivitis patients.[ncbi.nlm.nih.gov] She initially failed to respond to treatment with amphotericin B but the infection resolved following the introduction of oral itraconazole.[ncbi.nlm.nih.gov]