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101 Possible Causes for B3(Fv) PE38, Immunotoxin

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  • T-cell Acute Lymphoblastic Leukemia

    These recombinant immunotoxins were expressed in Escherichia coli and showed that nanobody immunotoxins have the benefits of easy soluble expression in a prokaryotic expression[ncbi.nlm.nih.gov] METHODS AND RESULTS: Three new types of immunotoxins, dhuVHH6-PE38, dVHH6-PE-LR, and dhuVHH6-PE-LR, were successfully constructed.[ncbi.nlm.nih.gov] In our previous efforts, we have successfully generated the monovalent and bivalent CD7 nanobody-based immunotoxins, which can effectively trigger the apoptosis of CD7-positive[ncbi.nlm.nih.gov]

    Missing: B3(Fv) PE38
  • Diphtheria Toxoid

    Ex-vivo treatment of donor bone marrow with anti-T-cell immunotoxins for prevention of graft-versus-host disease.[nature.com] Resimmune is an immunotoxin that is in clinical trials in Cutaneous T cell lymphoma patients.[en.wikipedia.org] Immunotoxins: a new approach to cancer therapy. Science 219 : 644–650. 15 Cawley, D.B., Herschman, H.R., Gilliland, D.G. and Collier. R.J. 1980.[nature.com]

    Missing: B3(Fv) PE38
  • Sambucus

    KEYWORDS: ribosome-inactivating proteins; Sambucus; endoglin (CD105); immunotoxin; transferrin[ncbi.nlm.nih.gov] The lack of toxicity of type 2 RIPs from Sambucus make them good candidates as toxic moieties in the construction of immunotoxins and conjugates directed against specific[ncbi.nlm.nih.gov]

    Missing: B3(Fv) PE38
  • Toxic Effect

    Abstract Immunotoxins are chimeric proteins consisting of a toxin coupled to an antibody.[ncbi.nlm.nih.gov] The percentage of AnnexinV cells was over 95% in both cell lines treated with 10 nM immunotoxin.[ncbi.nlm.nih.gov] A complete elimination of Raji clones was reached with the 10 nM immunotoxin, whereas a mixture of free RIP and mAb gave about 90% of clonogenic growth.[ncbi.nlm.nih.gov]

    Missing: B3(Fv) PE38
  • Promyelocytic Leukemia

    Immunotoxins, such as gemtuzumab ozogamicin, may find certain cancer cells and kill them without harming normal cells.[clinicaltrials.gov]

    Missing: B3(Fv) PE38
  • Trichosanthes Kirilowii

    Purification, partial characterization and use for preparation of immunotoxins . Eur J Biochem. 176 , 581–588 (1988). 4. Lee-Huang, S. et al.[nature.com]

    Missing: B3(Fv) PE38
  • Thiotepa

    Bju International 94(3): 317-321, 2004 Prevention of postoperative recurrence of human bladder carcinoma by intravesical instillation of immunotoxin, a clinical study .[eurekamag.com]

    Missing: B3(Fv) PE38
  • Shigella Dysenteriae

    […] efficient immunotoxins.[cordis.europa.eu] Toxins of this group are extensively used to form immunotoxins for targeted cytotoxic therapy, and knowledge of the translocation mechanism is essential for development of[cordis.europa.eu]

    Missing: B3(Fv) PE38
  • Methotrexate

    BMJ Case Rep. 2017 Oct 24;2017. pii: bcr-2017-221844. doi: 10.1136/bcr-2017-221844. Author information 1 Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Delhi, Delhi, India. Abstract Two cases of live caesarean scar ectopic pregnancies are presented. Beta human chorionic gonadotropin[…][ncbi.nlm.nih.gov]

    Missing: B3(Fv) PE38
  • Ureteral Obstruction

    Transgenic mice expressing hCD25 in podocyte (NEP25) were injected with 1.25 or 10 ng/g body wt of LMB2, a hCD25-targeted immunotoxin, subjected to unilateral ureteral ligation[ncbi.nlm.nih.gov]

    Missing: B3(Fv) PE38

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