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5,039 Possible Causes for Bone, cell, hematopoietic, marrow, or, stem, transplant

  • Stem Cell Transplant

    What It Is Types of Bone Marrow Transplant Bone marrow transplant is most commonly used to treat leukemia and lymphoma.[loyolamedicine.org] KEYWORDS: fungemia; fusarium; hematopoietic stem cell transplant; skin lesion[ncbi.nlm.nih.gov] […] proceed to transplant.[ncbi.nlm.nih.gov] Mantle cell lymphoma is a relatively rare malignancy, comprising fewer than 10% of all non-Hodgkin lymphomas.[ncbi.nlm.nih.gov] […] globulin followed by re-infusion of autologous stem cells as per standard institute protocol.[ncbi.nlm.nih.gov] This review summarizes background information about hematopoietic stem-cell transplantation and discusses the current role of the procedure.[nejm.org] […] associated with antibodies against red cells, platelets and granulocytes.[ncbi.nlm.nih.gov]

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  • Severe Aplastic Anemia

    The transplant protocol tested the hypothesis that the incidence of chronic GvHD could be reduced by limiting the marrow grafts to 2.5 10 8 nucleated marrow cells/kg.[ncbi.nlm.nih.gov] […] the registration data of the Japanese Society for Hematopoietic Cell Transplantation.[ncbi.nlm.nih.gov] The median age of the patients at the time of transplantation was 30 (range, 11 to 69) years.[ncbi.nlm.nih.gov] Although temozolomide is generally well tolerated with temporary myelosuppression as the primary dose-limiting toxicity, irreversible bone-marrow aplasia after treatment with[ncbi.nlm.nih.gov] Analysis of T cell subset chimerism showed that CD4 T cells were predominantly donor-derived at 1 year, whereas recipient-derived CD8 T cells shaped mixed chimerism with a[ncbi.nlm.nih.gov] The combination of CY and TBI and the infusion of sufficient peripheral blood stem cells may contribute to the successful engraftment.[ncbi.nlm.nih.gov] No giant proerythroblasts were found in her bone marrow at diagnosis.[ncbi.nlm.nih.gov]

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  • Hematopoietic Stem Cell Transplantation

    Clinical Services Bone Marrow/Hematopoietic Stem Cell Transplantation Program The University of Miami Miller School of Medicine’s pediatric bone marrow/hematopoietic stem[pediatrics.med.miami.edu] Allogeneic hematopoietic stem cell transplantation (allo-HSCT) still remains to be the curative treatment option for various non-malignant and malignant hematopoietic diseases[ncbi.nlm.nih.gov] KEYWORDS: bronchiolitis obliterans syndrome (BOS); hematopoietic stem cell transplantation (HSCT); lung transplantation (LTX)[ncbi.nlm.nih.gov] The time from diagnosis to transplant seems to influence negatively both OS (log-rank p KEYWORDS: Allogeneic stem cell transplantation; Cutaneous T cell lymphoma[ncbi.nlm.nih.gov] BACKGROUND: Proper stem cell mobilization is one of the most important steps in hematopoietic stem cell transplantation (HSCT).[ncbi.nlm.nih.gov] KEYWORDS: Allogeneic hematopoietic stemcell transplantation; Autologous hematopoietic stem cell transplantation; Geriatric patients[ncbi.nlm.nih.gov] Indeterminate cell histiocytosis (ICH) is a rare disease composed of so-called indeterminate cells, an alleged cutaneous dendritic cell subset displaying histological and[ncbi.nlm.nih.gov]

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  • Aplastic Anemia

    KEYWORDS: Aplastic anemia; Bone marrow failure; Hematopoietic stem cell transplantation; Immunobiology; Myelodysplastic syndromes; Novel therapies[ncbi.nlm.nih.gov] PURPOSE OF REVIEW: Improvements in allogeneic hematopoietic cell transplantation (HCT) with better donor selection, conditioning regimens and graft vs. host disease prophylaxis[ncbi.nlm.nih.gov] BACKGROUND: Acquired aplastic anemia (AA) is characterized by deficiency or dysfunction of the bone marrow (BM) microenvironment.[ncbi.nlm.nih.gov] Abstract We report here the preliminary results of allogeneic hematopoietic stem cell transplantation with mesenchymal stem cells (MSCs) for 6 cases of severe aplastic anemia[ncbi.nlm.nih.gov] Cell apoptosis on T cells and BMHSCs was also detected by FCM.[ncbi.nlm.nih.gov] A 21-year-old man with aplastic anemia was treated with an allogeneic stem cell transplant. He developed fatal Fusarium solani infection.[ncbi.nlm.nih.gov] In conclusion, DGBX can relieve the immune-mediated destruction of HSCs, repair hematopoietic failure, and recover the hematopoietic function of HSCs in hematogenesis.[ncbi.nlm.nih.gov]

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  • Fanconi Anemia

    Abstract More than 90% of Fanconi anemia (FA) patients experience progressive bone marrow failure during life with a median onset at 8 years of age.[ncbi.nlm.nih.gov] Abstract Hematopoietic cell transplantation for Fanconi Anemia (FA) has improved dramatically over the past 40 years.[ncbi.nlm.nih.gov] Abstract We developed a haploidentical transplantation protocol with post-transplant cyclophosphamide (CY) for in vivo T-cell depletion (TCD) using a novel adapted-dosing[ncbi.nlm.nih.gov] KEYWORDS: Fanconi anemia; bone marrow transplant; renal insufficiency; renal transplant[ncbi.nlm.nih.gov] In cell culture and transplantation models of FA, we further demonstrate that LV carrier cells migrate along SDF-1α gradients and transfer vector particles that stably integrate[ncbi.nlm.nih.gov] In addition, neural stem cells from FA mice had a reduced capacity to self-renew in vitro.[doi.org] Fanconi anemia (FA) is a rare inherited bone marrow failure syndrome associated with high risks of severe bone marrow failure (BMF), acute myeloid leukemia (AML), and solid[ncbi.nlm.nih.gov]

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  • Acute graft versus host disease

    This is called an autologous bone marrow transplant. Bone marrow cells are a major component of the immune system.[healthline.com] The risk of acute graft-versus-host disease (aGVHD) can be reliably estimated by the hematopoietic cell transplantation-specific comorbidity index (HCT-CI), which can be further[ncbi.nlm.nih.gov] […] and (ii) a composite endpoint of acute GVHD or death within 100 days post-transplant.[ncbi.nlm.nih.gov] KEYWORDS: Acute graft versus host disease; Allogeneic hematopoietic stem cell transplantation; Tc17 cells; Th17 cells[ncbi.nlm.nih.gov] […] allogeneic hematopoietic stem cell transplantation.[ncbi.nlm.nih.gov] Abstract Several genetic polymorphisms have been implicated to affect the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT).[ncbi.nlm.nih.gov] GVHD is not always a negative development following a blood and bone marrow transplant.[leukemiabmtprogram.org]

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  • Graft-versus-Host-Disease

    This is called an autologous bone marrow transplant. Bone marrow cells are a major component of the immune system.[healthline.com] Abstract A 30-year-old woman with myelodysplastic syndrome underwent allogeneic hematopoietic stem cell transplantation (HSCT) derived from her HLA-matched sister six years[ncbi.nlm.nih.gov] Allogeneic blood or marrow transplantation (alloBMT) may lead to long-term disease control in patients with multiple myeloma (MM).[ncbi.nlm.nih.gov] Alloreactive T cells infused with the stem cell inoculum may generate graft-versus-host disease (GVHD) representing one the most relevant obstacles to the successful outcome[ncbi.nlm.nih.gov] Abstract Graft-versus-host disease (GvHD) remains a major treatment-related risk in patients undergoing stem cell transplantation.[ncbi.nlm.nih.gov] BACKGROUND: Infection and graft-versus-host disease (GVHD) are among the most common complications after hematopoietic stem cell transplantation (HSCT).[ncbi.nlm.nih.gov] Abstract Allogeneic hematopoietic cell transplantation (HCT) is the treatment of choice for a variety of hematologic malignancies and disorders.[ncbi.nlm.nih.gov]

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  • Bone Marrow Transplant

    KEYWORDS: bone marrow transplantation; cerebral palsy; congenital bone marrow failure; mental retardation[ncbi.nlm.nih.gov] High-intensity treatments and complications after hematopoietic cell transplantation (HCT) injure normal tissues and may increase the risk of frailty even among nongeriatric[ncbi.nlm.nih.gov] Louis for a bone marrow transplant or stem cell transplant, you are cared for by one of the 10 largest bone marrow and stem cell transplant programs in the world.[barnesjewish.org] However, all 4 subjects showed prevalence of CD20 CD27 memory B cells around 6 months posttransplant when B cell counts were still low and the clonal B cell repertoire very[ncbi.nlm.nih.gov] Stem cell donation If it isn't possible to use your own stem cells for the transplant (see above), stem cells will need to come from a donor.[nhs.uk] Abstract We report 5 individuals in 3 unrelated families with severe thrombocytopenia progressing to trilineage bone marrow failure (BMF).[ncbi.nlm.nih.gov] Abstract Cutaneous squamous cell carcinomas arise as secondary cancers in hematopoietic stem cell transplant survivors.[ncbi.nlm.nih.gov]

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  • Juvenile Myelomonocytic Leukemia

    The inhibitory effect of TNF-a on normal hematopoiesis causes bone marrow suppression and results in anemia and thrombocytopenia.[78stepshealth.us] The two karyotypically abnormal clones might have developed from multipotential hematopoietic stem cells with the potential to differentiate into myeloid and B-lymphoid lineages[ncbi.nlm.nih.gov] transplant.[ncbi.nlm.nih.gov] */diagnosis Histiocytosis, Langerhans-Cell*/pathology Histiocytosis, Langerhans-Cell*/therapy Humans Japan Leukemia, Myelomonocytic, Juvenile*/diagnosis Leukemia, Myelomonocytic[ncbi.nlm.nih.gov] Gov't MeSH terms Cells, Cultured HEK293 Cells Humans Induced Pluripotent Stem Cells/cytology* Induced Pluripotent Stem Cells/metabolism Leukemia, Myelomonocytic, Juvenile[ncbi.nlm.nih.gov] Stem Cells/drug effects* Hematopoietic Stem Cells/metabolism Hematopoietic Stem Cells/pathology Humans Leukemia, Myelomonocytic, Juvenile/genetics* Leukemia, Myelomonocytic[ncbi.nlm.nih.gov] Gov't MeSH terms Cord Blood Stem Cell Transplantation/adverse effects Diseases in Twins/diagnosis Diseases in Twins/immunology Diseases in Twins/metabolism Diseases in Twins[ncbi.nlm.nih.gov]

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  • Hepatic Veno-Occlusive Disease

    Abstract Veno-occlusive disease (VOD) is a frequent complication early after bone marrow transplantation.[ncbi.nlm.nih.gov] Abstract Hepatic veno-occlusive disease (HVOD) after hematopoietic stem cell transplantation (HSCT) results in considerable morbidity and mortality.[ncbi.nlm.nih.gov] VOD has been described after all types of stem cell transplantation, irrespective of the stem cell source, type of conditioning therapy, or underlying disease.[ncbi.nlm.nih.gov] Abstract Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a complication that is typically associated with conditioning for hematopoietic stem cell[ncbi.nlm.nih.gov] Abstract Hepatic veno-occlusive disease (VOD) is a common and potentially devastating complication of hematopoietic stem cell transplantation.[ncbi.nlm.nih.gov] Veno-occlusive disease may now become a dose-limiting factor in the use of the combined high-dose mitomycin C-bone marrow transplantation therapy.[ncbi.nlm.nih.gov] On the 42nd day after CBT, he underwent living related liver transplantation (LRLT) with a left lateral segment graft from his father.[ncbi.nlm.nih.gov]

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