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286 Possible Causes for C11, Raclopride

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  • Ketamine

    (16) C12—C11—H11B 111.3 (12) C3—C4—H4 123.7 (13) C10—C11—H11A 106.8 (14) C5—C4—H4 115.9 (13) C12—C11—H11A 110.4 (13) C4—C5—C6 121.81 (16) H11B—C11—H11A 109.3 (17) C4—C5—H5[doi.org] These effects of dopamine were blocked by the dopamine D2 receptor antagonist (-)raclopride.[ncbi.nlm.nih.gov] […] clinically relevant doses caused a significant increase in the incorporation of [(35)S]GTP-gamma-S binding in CHO-cells expressing D(2) receptors, which was prevented by raclopride[ncbi.nlm.nih.gov]

  • Antipsychotic Agent

    Radioligands that are often used in these studies are [F18] Altanserin and [C11] MDL 100907 labeled, which have been administered to patients that are either drug-naïve or[ncbi.nlm.nih.gov] In each study, both PET scans with [ 11 C]raclopride and [ 11 C]FLB 457 were performed sequentially.[doi.org] After 2 weeks of treatment, D(2) receptor occupancy was determined with [(11)C]raclopride and positron emission tomography, and clinical response, extrapyramidal side effects[ncbi.nlm.nih.gov]

  • Sulpiride

    Increased synthesis of dopamine in prefrontal cortex and striatum in drug-naive schizophrenic patients studied by use of C11-labelled l-DOPA and positron emission tomography[doi.org] MATERIALS AND METHODS: Positron emission tomography scans were acquired in ten healthy volunteers with [11C]-raclopride.[ncbi.nlm.nih.gov] Iodobenzamide Isocorypalmine L-741,626 L-745,870 Levofenfluramine LEK-8829 Metergoline Metitepine (methiothepin) N-Methylspiperone Nafadotride Nuciferine PNU-99,194 Pridopidine Raclopride[en.wikipedia.org]

  • Phenylalanine Increased

    University of Cambridge (2008) Proc Physiol Soc 11, C11 Oral Communications Decreased Fischer’s ratio and increased cerebral delivery of phenylalanine after LPS infusion in[physoc.org] Iodobenzamide Isocorypalmine L-741,626 L-745,870 Levofenfluramine LEK-8829 Metergoline Metitepine (methiothepin) N-Methylspiperone Nafadotride Nuciferine PNU-99,194 Pridopidine Raclopride[en.wikipedia.org]

  • Schizophrenia

    Dopamine D2 receptor binding in drug-naïve patients with schizophrenia examined with raclopride-C11 and positron emission tomography .[ncbi.nlm.nih.gov] Cloned D2Long dopamine, using [ 3 H]raclopride (Seeman, 2001, 2002, 2006).[scholarpedia.org] Dopamine D2 receptor binding in drug-naïve patients with schizophrenia examined with raclopride-C11 and positron emission tomography.[doi.org]

  • Dysthymic Disorder

    Increased synthesis of dopamine in prefrontal cortex and striatum in drug-naive schizophrenic patients studied by use of C11-labelled l-DOPA and positron emission tomography[dx.doi.org] Their detailed pharmacodynamics are reported elsewhere. 69 , 70 Remoxipride and raclopride are two other recently described members of this class.[dx.doi.org] Distribution of dopaminergic receptors in the primate cerebral cortex: quantitative autoradiographic analysis using 3H raclopride, 3H spiperone and 3H SCH23390 Neuroscience[dx.doi.org]

  • Ecstasy

    ISI Szabo Z , McCann U D , Wilson A A , Scheffel U , Owonikoko T , Mathews W B , Ravert H T , Hilton J , Dannals R F , Ricaurte ( 2002 ) Comparison of ( )- 11C-McN5652 and C11[dx.doi.org] Comparison of methods for analysis of clinical [11C]raclopride studies. J Cereb Blood Flow Metab . 1996;16(1):42-528530554 PubMed Google Scholar Crossref 68.[archpsyc.jamanetwork.com]

  • Pipobroman

    InChI 1S/C10H16Br2N2O2/c11-3-1-9(15)13-5-7-14(8-6-13)10(16)2-4-12/h1-8H2 NJBFOOCLYDNZJN-UHFFFAOYSA-N N1(CCN(CC1)C(CCBr) O)C( O)CCBr alkylating agent Highly reactive chemical[ebi.ac.uk] InChI 1S/C10H16Br2N2O2/c11-3-1-9(15)13-5-7-14(8-6-13)10(16)2-4-12/h1-8H2 What’s the InChIKey format of pipobroman?[molinstincts.com] Molecular Weight 356.05424 g/mol IUPAC Name 3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one SMILES String BrCCC( O)N1CCN(CC1)C( O)CCBr InChI InChI 1S/C10H16Br2N2O2/c11[molinstincts.com]

    Missing: Raclopride
  • Aripiprazole

    (Bottom) Typical [ 11 C]raclopride brain PET images before and after 30 mg of aripiprazole (OPC 14597).[dx.doi.org] Figure 1 (Top) Typical [ 11 C]raclopride brain positron emission tomography (PET) images before and after 2 mg of aripiprazole (OPC 14597).[dx.doi.org] Dopamine D 2 and D 3 receptor occupancy in fifteen normal male human brains was measured using positron emission tomography (PET) with [ 11 C]raclopride.[dx.doi.org]

    Missing: C11
  • Guanadrel

    InChI 1S/C10H19N3O2/c11-9(12)13-6-8-7-14-10(15-8)4-2-1-3-5-10/h8H,1-7H2,(H4,11,12,13) HPBNRIOWIXYZFK-UHFFFAOYSA-N adrenergic antagonist An agent that binds to but does not[ebi.ac.uk] Interactive image ChEBI CHEBI:5555 ChEMBL ChEMBL1037 ChemSpider 35305 IUPHAR/BPS 7193 KEGG D08029 MeSH C004945 PubChem CID 38521 UNII 765C9332T4 InChI InChI 1S/C10H19N3O2/c11[en.wikipedia.org] Weight 213.2768 Optical Activity ( / - ) Defined Stereocenters 0 / 1 E/Z Centers 0 Charge 0 SHOW SMILES / InChI InChI InChIKey HPBNRIOWIXYZFK-UHFFFAOYSA-N InChI 1S/C10H19N3O2/c11[drugs.ncats.io]

    Missing: Raclopride

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