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98 Possible Causes for CCR3

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  • Lymphomatoid Papulosis

    Both tissues were negative for regulated upon activation, normal T-cell expressed and secreted (RANTES) and CCR3.[] Chemokine studies in a subset of 25 patients showed chemokine receptor (CCR) CCR4( ) and thymus and activation-related chemokine (TARC( )) in all LyP types and CCR3( ) and[] Additionally, data have shown an increased risk of associated lymphomas in lymphomatoid papulosis cases with CCR3 atypical cells or the 30M362 allelic form of the CD30 promoter[]

  • Eosinophilic Leukemia

    Abstract Leukotactin-1 (Lkn-1)/CCL15 is a CC chemokine that binds to the CCR1 and CCR3.[]

  • Anti-HIV Agent

    TCS also significantly augmented chemokine-stimulated activation of chemokine receptors CCR5 and CXCR4 as well as CCR1, CCR2B, CCR3, and CCR4 transiently expressed in HEK293[] Hoffman TL, Stephens EB, Narayan O, Doms RW (1998) HIV type I envelope determinants for use of the CCR2b, CCR3, STRL33, and APJ coreceptors.[] Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, Wu L, Mackay CR, LaRosa G, Newman W, Gerard N, Gerard C, Sodroski J (1996) The beta-chemokine receptors CCR3 and[]

  • Renal Transplant Rejection

    CCR1 mRNA was detectable in both allografts and controls, but CCR3 and CCR8 were absent.[] […] receptor phenotype is associated with types of immune responses, ie, T helper subtype 1 (Th1; CXC chemokine receptor 3 [CXCR3], CC chemokine receptor 5 [CCR5]) versus Th2 (CCR3[] The upregulation of the CXCR3 ligand IP-10, as well as CCR5 and its ligands, in the absence of CCR3 and CCR8 is indicative that renal allograft rejection is primarily the[]

  • AIDS Dementia Complex

    Abstract The chemokine receptor CCR5 and to a lesser extent CCR2b and CCR3 have been shown to serve as coreceptors for HIV-1 entry into macrophages.[] Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates . J.[] Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia . Exp. Mol. Pathol. 69 , 192–201 (2000). 47.[]

  • Eosinophilic Pustular Folliculitis

    Indomethacin down-modulated cell surface expression of both CRTH2 and CCR3.[] […] regard, we have recently demonstrated a peculiar pharmacological action of indomethacin; down-modulation of the expressions and functions of CRTH2, a PGD2 receptor, and CCR3[] […] migration to PGD2 and, to a much lesser extent, to eotaxin (CCL11); these effects could be mediated by homologous and heterologous desensitization of eosinophil CRTH2 and CCR3[]

  • Autoimmune Thrombocytopenia

    This activation by Tat requires the chemokine receptor CCR3 and β3-integrin expression on platelets, as well as calcium flux.[]

  • Behçet Disease

    Imputation analyses of genome wide association studies revealed new associations such as ERAP-1, CCR1-CCR3, KLRC4 and STAT4.[] Met694Val TLR4 (involved in pathogen recognition and activation of innate immunity) ERAP1 (codes for a molecule that processes microbial proteins in white blood cells) CCR1-CCR3[]

  • Schistosomiasis Mansoni

    Our main focus has been on the plasma chemokines (CXCL8/CCL2/CCL3/CCL24) and chemokine receptors (CCR2/CCR3/CCR5/CXCR1/CXCR2/CXCR3/CXCR4) expressed by circulating eosinophils[] Although no differences were detected for beta-chemokine receptors (CCR2, CCR3 and CCR5) or alpha-chemokine receptors (CXCR3 and CXCR4), a significantly lower frequency of[]

  • Anaplastic Large Cell Lymphoma

    One study showed that CCR3 was expressed by atypical lymphoid cells in 10 (83%) of 12 cases of ALCL but in only 5 (38%) of 13 cases of LyP.[] RANTES was strongly expressed by lymphoma cells in ALCL (11 [92%] of 12) but was weak or sporadic in LyP (7 [54%] of 13). [39] The presence of CCR3 and its ligand, RANTES,[]

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