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292 Possible Causes for CFTR, Inbred, Mice

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  • Croton

    […] chemistry Diterpenes/isolation & purification Diterpenes/pharmacology* Gene Expression Regulation Human Umbilical Vein Endothelial Cells Humans Hydrogen Bonding Mice Mice, Inbred[] Acute and sub- acute toxicity studies of the crude extracts were carried out in Swiss albino mice.[] Both extracts inhibited a time- and voltage-independent Cl- conductance, which indicated the involvement of CFTR Cl- channels.[]

  • Lactococcus Lactis

    BALB C Mice, Inbred C57BL Papillomavirus E7 Proteins/immunology* Papillomavirus Infections/prevention & control* Plasmids Staphylococcus aureus T-Lymphocytes, Cytotoxic/immunology[] Cured mice remained responsive to disease-unrelated antigens, which argues against excessive immunosuppression.[] CFTR.[]

  • Carbachol

    Conductance Regulator/metabolism Endocytosis/drug effects* Endosomes/drug effects Endosomes/metabolism Enterocytes/drug effects* Enterocytes/metabolism Humans Male Mice Mice, Inbred[] All four secretory stimuli resulted in brush-border membrane (BBM) recruitment of CFTR in crypts and villi.[] Mice, Inbred C57BL Microscopy, Confocal Mucins/metabolism* Protein Transport Sodium-Hydrogen Exchanger 3 Sodium-Hydrogen Exchangers/metabolism* Time Factors Substances CFTR[]

  • Adenovirus

    BALB C Mice, Inbred C57BL Mice, Knockout Protein Binding Receptors, Immunologic/genetics Receptors, Immunologic/metabolism* Receptors, Immunologic/physiology* Virus Internalization[] […] generated rAd2-ZGP, a recombinant replication-incompetent adenovirus serotype 2 expressing codon-optimized Zaire ebolavirus glycoprotein, and evaluated its immunogenicity in mice[] The idea has great promise: for instance, a functional CFTR gene could be delivered to cells in people with cystic fibrosis, replacing the defective gene and restoring the[]

  • Asthma

    […] blood Epitopes, B-Lymphocyte/immunology* Epitopes, T-Lymphocyte/blood Epitopes, T-Lymphocyte/immunology* Female Gene Expression Regulation/immunology* Humans Male Mice Mice, Inbred[] […] smoke: rs8069176 rs2305480 rs4795400 Related genes: TNF ADH1C ORMDL3 TBX21 , for which at least six SNPs have been reported to be associated with several asthma subtypes CFTR[] Compared to wild-type mice, IL-32γ transgenic mice show decreased levels of inflammatory cells, recruited eosinophils, and lymphocytes in bronchoalveolar lavage fluid in a[]

  • Methylmalonic Acidemia

    […] analysis Glutathione/metabolism Homozygote Humans Male Methylmalonyl-CoA Mutase/deficiency Methylmalonyl-CoA Mutase/genetics* Methylmalonyl-CoA Mutase/metabolism* Mice Mice, Inbred[] Metabolite studies defined the magnitude and tempo of plasma MMA concentrations in the mice.[] The following genes are required for Invitae carrier screening and will be added to your order, CFTR (cystic fibrosis), SMN1 (spinal muscular atrophy), FMR1 (fragile X syndrome[]

  • Coffin-Lowry Syndrome

    Animals Coffin-Lowry Syndrome/genetics* Coffin-Lowry Syndrome/metabolism Disease Models, Animal Gene Expression Profiling Hippocampus/enzymology* Humans Male Mice Mice, Inbred[] The following genes are required for Invitae carrier screening and will be added to your order, CFTR (cystic fibrosis), SMN1 (spinal muscular atrophy), FMR1 (fragile X syndrome[] To discriminate between periodontal bone loss and systemic bone loss, we additionally crossed Rsk2-deficient mice with transgenic mice overexpressing the osteoanabolic transcription[]

  • Mucolipidosis

    Abstract Two brothers, offspring of an Arab inbred family suffered from both mucolipidosis III (ML-III) and Bardet-Biedl syndrome (BBS).[] In osteoclasts, no morphological or functional abnormalities are detected whereas osteoclastogenesis is dramatically increased in MLII mice.[] The Cystic Fibrosis Carrier Status test is indicated for the detection of 28 variants in the CFTR gene and is most relevant for people of Ashkenazi Jewish, European and Hispanic[]

  • Spinal and Bulbar Muscular Atrophy

    Gov't MeSH terms Aged Animals Autophagy/genetics Disease Models, Animal Female Gene Expression Regulation/genetics Humans Inclusion Bodies/pathology* Male Mice Mice, Inbred[] In vivo, SBMA transgenic mice overexpressing a muscle-specific isoform of IGF-1 selectively in skeletal muscle show evidence of increased Akt activation and AR phosphorylation[] Adrenoleucodistrofie/adrenomieloneuropatie (ALD/AMN) Alele HLA asociate cu boala celiaca Alele HLA asociate cu narcolepsia Aplazia congenitala a ductelor deferente, CBAVD (CFTR[]

  • Polycystic Liver Disease

    C57BL Rats, Inbred F344 Receptors, Vasopressin/metabolism Vasopressins/physiology* Substances Keratin-19 Receptors, Vasopressin Vasopressins Cyclic AMP Supplementary concept[] METHODS: PC2/AC6 double conditional knockout (KO) mice were generated (Pkd2/AC6 KO) and compared to Pkd2 KO mice.[] Basolateral secretin stimulates intracellular cAMP signaling and bicarbonate fluid rich secretion by activation of apical CFTR chloride channel.[]