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9,109 Possible Causes for CLC 6, channel, chloride, human, protein

Did you mean: CLC 6, channel, chloride, human, proteus

  • Trypanosoma Brucei

    TLF-1 is a subclass of high density lipoprotein particles defined by two primate-specific apolipoproteins: the ion channel-forming toxin ApoL1 (apolipoprotein L1) and the[ncbi.nlm.nih.gov] Upon expression in Xenopus oocytes, all three proteins induce similar outward rectifying chloride ion currents.[ncbi.nlm.nih.gov] Springer Science & Business Media , 1 dic 2013 - 346 pagine Human African Trypaniosomiasis (HAT) or sleeping sickness is an old disease to be now considered as reemergent.[books.google.it] All together our results demonstrate that TbTim62, a unique mitochondrial protein in T. brucei, is required for the formation of a stable TbTim17 protein complex.[ncbi.nlm.nih.gov] The outlines of the cells have been traced in the phase contrast channel and are projected onto the stained pictures.[mcponline.org]

  • Osteoporosis

    Six DEmRNAs [diacylglycerol O‑acyltransferase 2, potassium voltage‑gated channel subfamily S member 1, peptidase inhibitor 3, secretory leukocyte peptidase inhibitor, galectin‑related[ncbi.nlm.nih.gov] Intervention • The participant took 680 mg daily of strontium chloride for 2.5 y.[ncbi.nlm.nih.gov] Abstract Abaloparatide is a synthetic 34-amino acid peptide analogue of the 1-34 portion of the human parathyroid hormone-related protein (PTHrP).[ncbi.nlm.nih.gov] […] phosphorylated‑protein kinase B (AKT) protein expression in osteoblasts in vitro.[ncbi.nlm.nih.gov] To visualize region-specific structural bony alterations with age, the bone mineral density (Hounsfield units) was additionally analyzed in 168 human proximal tibiae.[ncbi.nlm.nih.gov]

    Missing: CLC 6
  • Ovariectomy

    Both endothelial SK3 and IK1 channels are functionally coupled to TRPV4 (transient receptor potential, vanilloid type 4) channels: the activation of TRPV4 channels activates[ncbi.nlm.nih.gov] Further, we showed that Cyanidin Chloride protects against ovariectomy-induced bone loss in vivo.[ncbi.nlm.nih.gov] While native blood group A-like glycans have not been demonstrated in prokaryotic microorganisms as a source of human "natural" anti-A isoagglutinin production, and metazoan[ncbi.nlm.nih.gov] CD56 and CD16 are recognized as specific NK markers in the dogs as well as in humans. Surgical interventions suppress NK cells both in rats and humans.[ncbi.nlm.nih.gov] The data are consistent with an ovariectomy-induced increase and estrogen-induced decrease in L-type calcium channel density in rabbit myocardium.[jpet.aspetjournals.org]

    Missing: CLC 6
  • Phenformin

    Phenformin reduced the open probability of Kir6.1/SUR2B channels by approximately 90% in inside-out patches.[ncbi.nlm.nih.gov] They received either moroxydine chloride in a dose of 0.04 g/kg a day or no specific treatment.[ncbi.nlm.nih.gov] Abstract The effects of the oral hypoglycemic agent, phenformin, were studied on the binding of 125I-insulin to its receptors in IM-9 human cultured lymphocytes.[ncbi.nlm.nih.gov] Activation of the unfolded protein response (UPR) is associated with the disruption of endoplasmic reticulum (ER) homeostasis and has been implicated in the pathogenesis of[ncbi.nlm.nih.gov] Abstract Metformin, a biguanide that has been used to treat type 2 diabetes mellitus, is reportedly transported into human hepatocytes by human organic cation transporter[ncbi.nlm.nih.gov]

    Missing: CLC 6
  • Atypical Teratoid Rhabdoid Tumor

    […] drug therapy Teratoma/metabolism* Substances Anti-Inflammatory Agents, Non-Steroidal Antineoplastic Agents Chloride Channels Hypoglycemic Agents Potassium Channels Niflumic[ncbi.nlm.nih.gov] Even though no increased recurrence rate seems to be reported in patients with brain tumors receiving recombinant human growth hormone (rhGH) replacement, in some patients[ncbi.nlm.nih.gov] This case emphasizes the importance of immunostaining for INI1 protein for distinguishing CPC from AT/RT in cases with atypical or indeterminate features.[ncbi.nlm.nih.gov] OBJECTIVE: This study investigated epigenetic modifications in human central nervous system atypical teratoid rhabdoid tumors (AT/RTs), in response to inhibition of insulin-like[ncbi.nlm.nih.gov] The impact of let-7b miRNA on HMGA2 expression and the malignant potential of human rhabdoid tumor cell G401 (SMARCB1(-/-)) were investigated by antisense inhibition and ectopic[ncbi.nlm.nih.gov]

    Missing: CLC 6
  • Myotonia Congenita

    INTRODUCTION: Myotonia congenita (MC) is caused by congenital defects in the muscle chloride channel CLC-1.[ncbi.nlm.nih.gov] "Extracellular magnesium and calcium reduce myotonia in ClC-1 inhibited rat muscle". Neuromuscular Disorders . 23 (6): 489–502. doi : 10.1016/j.nmd.2013.03.009 .[en.wikipedia.org] Abstract Myotonia congenita is a hereditary muscle disorder caused by mutations in the human voltage-gated chloride (Cl(-)) channel CLC-1.[ncbi.nlm.nih.gov] Our study addresses two points: 1) molecular genetic diagnostics of MC by analysis of the CLCN1 gene and 2) structural analysis of mutations in the homology model of the human[ncbi.nlm.nih.gov] OBJECTIVE: To determine the functional consequences of missense mutations within the skeletal muscle chloride channel gene CLCN1 that cause myotonia congenita.[ncbi.nlm.nih.gov]

  • Desipramine

    Finally, desipramine triggered apoptosis in cells expressing hERG channels.[ncbi.nlm.nih.gov] Desipramine's effect on acid ceramidase appeared specific for amphiphilic agents (desipramine, chlorpromazine, and chloroquine) but not other lysomotropic agents such as ammonium chloride[ncbi.nlm.nih.gov] In dissociated human submandibular acinar cells, desipramine inhibited intracellular pH recovery in a concentration-dependent manner.[ncbi.nlm.nih.gov] Immunoblotting revealed that 100 mmol/L desipramine activated extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein[ncbi.nlm.nih.gov] TH mRNA levels were determined by Northern blot in vitro, and by in situ hybridization ex vivo; TH protein levels were measured by western blot.[ncbi.nlm.nih.gov]

    Missing: CLC 6
  • Phenothiazine

    […] such as the human ether-a-go-go-related gene (hERG) channel, which plays a central role in arrhythmogenesis.[ncbi.nlm.nih.gov] MATERIALS AND METHODS: SaOS-2 cells were treated with the photosensitizer phenothiazine chloride before irradiation with matched laser light.[ncbi.nlm.nih.gov] BACKGROUND: The metabolism of phenothiazine neuroleptics (promazine, perazine) in a primary culture of human hepatocytes after pretreatment of cells with those neuroleptics[ncbi.nlm.nih.gov] In this work, the molecular recognition of methylene blue by two globular proteins, hemoglobin and lysozyme was characterized by employing fluorescence, circular dichroism[ncbi.nlm.nih.gov] […] promazine in human liver. 2.[ncbi.nlm.nih.gov]

    Missing: CLC 6
  • Ethanol

    Isoflurane increased the probability of channel opening.[ncbi.nlm.nih.gov] Abstract We describe a case of a 51-year-old man who ingested methylene chloride and presented with the classical clinical features.[ncbi.nlm.nih.gov] AntagomiR-451 efficiently protected GES-1 cells and primary human GECs from ethanol-induced viability reduction and apoptosis.[ncbi.nlm.nih.gov] Therefore, the present study was undertaken to evaluate the role of ABC transporters and heat shock proteins mediated response in human neural precursor cells (NPCs) and its[ncbi.nlm.nih.gov] Also incompatible with potassium dioxide, bromine pentafluoride; acetyl bromide; acetyl chloride; platinum, sodium.[chemicalbook.com]

    Missing: CLC 6
  • Probucol

    Here, we investigated the mechanisms of probucol effects on I hERG and hERG-channel expression.[ncbi.nlm.nih.gov] chloride; 3-fluorobenzyl chloride; (3,4-dichlorobenzyl) chloride; 2- pale benzyl bromide; 4- Yue-methoxybenzyl chloride; 4- Yue benzyl chloride; inter-methylbenzyl chloride[patents.google.com] METHODS: Human glioma U87 and glioblastoma SF295 cell lines were used. Cell proliferation was accessed using the cell proliferation assay and BrdU incorporation.[ncbi.nlm.nih.gov] Abstract Probucol, an antioxidative and hypolipidemic agent, has been postulated to increase reverse cholesterol transport by enhancing cholesteryl ester transfer protein[ncbi.nlm.nih.gov] The present study examined whether the decreased level of ADMA by probucol is related to enhancement of protein arginine methyltransferase I (PRMT I) expression and reduction[ncbi.nlm.nih.gov]

    Missing: CLC 6