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3,339 Possible Causes for COA

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  • Invasive Ductal Carcinoma

    […] survival with acyl-CoA oxidase 1 positivity (p 0.027).[ncbi.nlm.nih.gov] […] lipid metabolism-related proteins including hormone-sensitive lipase (HSL), perilipin A, fatty acid binding protein (FABP)4, carnitine palmitoyltransferase (CPT)-1, acyl-CoA[ncbi.nlm.nih.gov] Univariate analysis found associations of shorter disease-free survival with CPT-1 positivity (p 0.004) and acyl-CoA oxidase 1 positivity (p 0.032) and of shorter overall[ncbi.nlm.nih.gov]

  • Antimetabolite

    […] involved in CoA biosynthesis or utilization.[ncbi.nlm.nih.gov] This compound may be excreted with the urine, or it may be transaminated and converted to acetyl-CoA.[watcut.uwaterloo.ca] Its close structural resemblance to pantothenic acid, the vitamin precursor of coenzyme A (CoA), and its Michael acceptor moiety suggest that it irreversibly inhibits an enzyme[ncbi.nlm.nih.gov]

  • Aging

    Argan oil protected the liver against LPS toxicity and interestingly enough preservation of peroxisomal acyl-CoA oxidase type 1 (ACOX1) activity against depression by LPS.[ncbi.nlm.nih.gov]

  • Bacteroides Gingivalis

    These eleven strains were the only organisms which gave a positive reaction using the CoA test.[ncbi.nlm.nih.gov] B. gingivalis was the only organism tested which gave a specific positive reaction with the CoA reagent.[ncbi.nlm.nih.gov]

  • Low Protein Diet

    The activity of propionyl-CoA carboxylase in leucocytes was about 20% of the normal activity.[ncbi.nlm.nih.gov] These metabolites are all known to be associated with propionyl-CoA accumulation. Free propionic acid was not detected in the urine.[ncbi.nlm.nih.gov] In addition, the urine contained 3-oxo-2-methylvaleric acid and 3-hydroxy-2-methylvaleric acid, probably formed by condensation of two molecules of propionyl-CoA.[ncbi.nlm.nih.gov]

  • Developmental Disabilities

    Long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency is a rare autosomal recessive disorder with varied expression, from severe hypoglycemia and possible sudden infant[ncbi.nlm.nih.gov]

  • Coarctation of the Aorta

    What are the symptoms of COA in a child?[cedars-sinai.edu] Also known as: COA What is Coarctation of the Aorta (COA)? Coarctation of the aorta is a heart condition that is present at birth involving the narrowing of the aorta.[nicklauschildrens.org] Your child has been diagnosed with coarctation of the aorta (COA). COA is a narrowing in the aorta.[saintlukeshealthsystem.org]

  • Digitalis

    In this work, the Arabidopsis thaliana HMG1 cDNA, coding the catalytic domain of 3-hydroxy-3-methylglutaryl CoA reductase (HMGR1S), a key enzyme of the MVA pathway, was expressed[ncbi.nlm.nih.gov]

  • Klebsiella

    In S. malonica and K. oxytoca, malonyl-CoA decarboxylase was active only after growth with malonate; malonyl-CoA: acetate CoA transferase was found as well.[kops.uni-konstanz.de] These results indicate that malonate fermentation by these bacteria proceeds via malonyl-CoA mediated by a CoA transferase and that subsequent decarboxylation to acetyl-CoA[kops.uni-konstanz.de] […] actually malonyl-CoA was the substrate of decarboxylation.[kops.uni-konstanz.de]

  • Anisakis

    One cDNA clone, designated as α-methylacyl CoA racemase (Amacr) contained a 1,412 bp cDNA transcript with a single open reading frame that encoded 418 amino acids.[ncbi.nlm.nih.gov]

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