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Did you mean: cortisone, ENZYME, IMMUNOASSAY, SALIVARY

  • Cortisone

    No mutations affecting enzyme activity were identified in the HSD11B1 gene. Expression and activity assays demonstrate loss of function for all reported H6PDH mutations.[] Most routine laboratories measure cortisol levels using immunoassay tests which fail to determine low cortisol levels accurately due to the numerous interfering substances[] […] versus salivary cortisol.[] METHODS: We compared salivary liquid chromatography tandem mass spectroscopy cortisol and cortisone responses to those of serum cortisol measured on the Roche E170 immunoassay[]

  • Smoking

    Smoking is associated with the induction of the CYP 1A2 enzyme, and hence with diminished levels of drugs metabolized by this enzyme.[] Immunoassays for fentanyl were used in the service. In some cases, false negative results occurred.[] Point-prevalence abstinence was biochemically-verified by salivary cotinine at Week 1 and by exhaled carbon monoxide at Week 1, end-of-treatment, 6 and 12 months following[] Biochemical parameters were analyzed: total cholesterol, LDL-c, HDL-c, triglycerides, glucose, cortisol and insulin.[]

  • Adrenal Insufficiency

    Patients with partial deficiencies of steroidogenic enzymes are at risk to be misdiagnosed if adrenal function is not assessed.[] This paper reviews the limitations of immunoassay and liquid chromatography-tandem mass spectrometry (LC-MS/MS) in the measurement of total cortisol, the challenges of measuring[] […] cortisol levels, high ACTH levels, low serum aldosterone levels, high plasma renin activity Note: late night (11 pm to midnight) salivary cortisol level testing is also useful[] We aimed to investigate the value of basal cortisol level for prediction of AI.[]

  • Vegan Diet

    The fecal enzyme activities returned to normal values within 2 wk of resuming the conventional diet.[] […] obtained from fasting patients were determined by colorimetric methods, 25-hydroxyvitamin D by the chemiluminescence method and bone turnover markers by specific enzyme immunoassays[] Salivary pH showed no significant change in either subgroup.[] Think of cortisol as the puppet master, and a greedy one at that. Cortisol pulls the strings, and when it is too high, it will steal from our other sex hormones.[]

  • Ethosuximide

    These parameters could not be measured for other enzymes, since metabolite concentrations formed were below the HPLC detection limits. 5.[] Abstract We evaluated a new fluorescence polarization immunoassay (FPIA) for ethosuximide in the Abbott TDx and compared results with those by two other ethosuximide immunoassays[] CL/F was 0.0089 ( /- .0020) when the 120-h salivary concentration was used.[] BACKGROUND: Antiepileptics may affect cortisol metabolism through CYP3A4. There is little known about ethosuximide.[]

  • Thyroid Cancer

    We found that 6PGD mRNA, protein and enzyme activity levels are significantly upregulated in ATC cells during the prolonged exposure to doxorubicin in a time-dependent manner[] They are not currently as sensitive as Tg immunoassays and it is likely these assays will, like immunoassays, be limited by Tg heterogeneity and standardization issues, although[] Abstract Dear Editor, I read with great interest the article by Son et al about the radioprotective effect of selenium (Se) supplementation for the salivary glands from 131[] Serum cortisol, adrenocorticoitropic hormone, dehydroepiandrostenedione sulfate, and urinary free cortisol were elevated 8, 20, 4.4, and 340 folds, respectively.[]

  • Alzheimer Disease

    […] hypometabolism on F-deoxyglucose positron emission tomography and voxel-based statistical parametric mapping analysis, and tau and amyloid beta-42 in the cerebrospinal fluid with enzyme-linked[] […] interleukin [IL]-1β, IL-1ra, IL-2, IL-4, IL-6, IL-10, IL-17, interferon-γ, tumor necrosis factor-α, and vascular endothelial growth factor) was analyzed using a multiplex immunoassay[] In a case-control study, we assessed whether the cortisol response at awakening and diurnal cortisol would reflect these changes.[] Serum endocan levels were measured with an enzyme-linked immunosorbent assay kit.[]

  • Testosterone

    Abstract The steroidogenic enzyme 21-hydroxylase is necessary for the synthesis of both glucocorticoids and mineralocorticoids. 21-hydroxylase is a cytochrome P-450 enzyme[] When compared to LC-MS/MS, more immunoassays under-recovered in men and women and over-recovered in boys and girls.[] Salivary testosterone was measured using the Salimetrics test.[] Measurement of cortisol and testosterone in athletes: Accuracy of LC-MS/MS assays for cortisol and testosterone measurement in whole-blood microspecimens.[]

  • Caffeine

    We investigated the potential drug-drug interaction effect of OCA on metabolic CYP450 enzymes and drug transporters.[] OBJECTIVE: Evaluate whether saliva could be a useful alternative to serum for routine therapeutic drug monitoring of caffeine in preterm infants using the enzyme multiplied immunoassay[] Specifically, a single-point concentration of salivary caffeine (total overnight salivary caffeine assessment [TOSCA]) after an overnight period of the caffeinated beverages[] State anxiety, negative emotion, and salivary cortisol were heightened both 45 and 75 min after caffeine intake relative to placebo.[]

  • Dextromethorphan

    The ¹³C-dextromethorphan breath test (DM-BT), labeled with ¹³C at the O-CH3 moiety, measures CYP2D6 enzyme activity.[] Most of the initial screens use a specific type of immunoassay, the enzyme multiplied immunoassay technique (EMIT), (Dade Behring, San Francisco, CA) because of its low level[] DXM administration significantly increased MMN amplitudes but not salivary cortisol concentrations.[] Dextromethorphan (DEX) was used as common probe for CYP2D6 and CYP3A4 enzymes.[]

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