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109 Possible Causes for CYSTEINE, INHIB, PROTEASE

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  • Exfoliative Ichthyosis

    […] proteasematriptase leads to autosomal-recessive ichthyosis accom-panied by disturbance of the stratum corneum,24,25 butalso a defect in themouse ortholog of thematriptase inhib-itor[] Autosomal recessive exfoliative ichthyosis (AREI) results from mutations in CSTA, encoding cysteine protease inhibitor A (cystatin A).[] We show here evidence of a key role for a protease inhibitor in epidermal adhesion within the lower layers of the human epidermis.[]

  • HIV-proteinase Inhibitor

    Inhib. 6 , 65–98 (1992) 3 Norbeck, D.W. & Kempf, D.J. HIV protease inhibitors. Ann. Rep. med.[] It contains inhibitors of multiple cysteine and serine protease families.[] J Enzyme Inhib 2:1–22.[]

  • Anti-HIV Agent

    J Enzyme Inhib Med Chem 28(1):113–122 PubMed CrossRef Google Scholar 72.[] WEB RESOURCES Links to other new chemotherapeutic approaches to treating HIV infection HIV therapy tricks cell into suicide Thiol-based reagents N-acetyl cysteine and procysteine[] 抄録 Selective and potent HIV protease inhibitors containing allophenylnorstatine [Apns; (2S, 3S)-3-amino-2-hydroxy-4-phenylbutyric acid] as a transition-state mimic were designed[]

  • Hereditary Angioedema Type 3

    Se origina por la ausencia o la deficiencia funcional del inhibidor de la C1 esterasa (C1-INH), que en condiciones normales inhibe la actividad proteolítica de la primera[] Following these discoveries, researchers identified the association of the deficiency of C1-INH with the superfamily of genes known as serine (or cysteine) peptidase inhibitors[] C1 esterase inhibitor (C1-INH) is a protease inhibitor that blocks the activation of the classic complement pathway, but there are also many others biochemical pathways, including[]

  • Alpha 2 Macroglobulin Deficiency

    Se conocen otras nuevas proteínas con funciones reguladoras como la hepcidina (Hpc), hor- mona de síntesis hepática que inhibe la expresión de la ferroportina y del DMT1 con[] A2M is able to inactivate many kinds of proteinases (including serine-, cysteine-, aspartic- and metalloproteinases).[] […] nicotine normal obstructive pulmonary disease oxidants panniculitis pathogenesis patients with alpha-1 patients with severe Pediatr pharmacotherapy phenotype physema PiZZ protease[]

  • Hereditary Angioedema Type 1

    […] disorders of bradykinin metabolism, attacks being generated by an imbalance between production and degradation with over production of the mediator due to lack of the C1 inhib[] Specifically, serine (or cysteine) peptidase inhibitor (SERPIN) genes located on chromosome 11 code for C1-INH and more than 450 missense, nonsense, deletions, or insertion[] C1 esterase inhibitor (C1-INH) is a protease inhibitor that blocks the activation of the classic complement pathway, but there are also many others biochemical pathways, including[]

  • Dermatosparaxis

    Este trastorno del tejido inhibe la capacidad del cuerpo de producir colágeno provocando que la piel se atrofie.[] The pNPI enzyme is a metalloproteinase containing properdin repeats and a cysteine-rich domain with similarities to the disintegrin domain of reprolysins.[] Hereceived his Ph.D in 1984 from the University of Leeds with a thesison the "Metabolism of Neuropeptides by Cell-surface Peptidases" whichstimulated his interest in proteases[]

  • Congenital Alpha-2-Antiplasmin Deficiency

    ADP, collagen, Epi, and thrombin Rx: DDAVP (promotes release of vWf and factor VIII); platelet txfusions Term Acquired platelet fxn disorder - ASA, NSAIDs Definition COX inhib[] […] use a nucleophilic cysteine residue, rather than a serine, in their active site.[] (i.e., conformationally abnormal) protease molecules that accumulate in tissue.[]

  • Lactococcus Lactis

    Les cations bivalents Hg 2 et Cu 2 inhibent l'activité de l'estérase.[] Interestingly, replacement of the 4th cysteine residue (pISTY215) reduced antigenicity of the recombinant protein.[] By contrast, the effects of protease-treated metabolites on the AGS cell line verified the protein nature of anti-cancer metabolites.[]

  • Mannose-Binding Lectin Deficiency

    Die A-ketting (RTA) in die B-ketting (RTB), met die hulp van maklik deur selmembrane, skade aan 60S ribosomale subeenheid en proteïensintese inhibeer, wat lei tot seldood.[] A secreted protein with plant-specific cysteine-rich motif functions as a mannose-binding lectin that exhibits antifungal activity.[] IgM innate immunity mannose-binding lectin (MBL) mannose-binding lectin-associated serine protease (MASP) murine model pathogen Footnotes 23rd International Lectin Meeting[]