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10,912 Possible Causes for Cell, Component, Present, Spindle

  • Dedifferentiated Liposarcoma

    Abstract A 75-year-old male presented with complaint of painless left inguinoscrotal mass slowly increasing in size since 9 years.[ncbi.nlm.nih.gov] The latter was composed predominantly of loosely arranged, benign-appearing spindle cells and fat cells.[ncbi.nlm.nih.gov] […] well-differentiated liposarcoma component.[ncbi.nlm.nih.gov] In normal adipose-derived stem cells, C/EBPα expression was strongly induced when cells were cultured in differentiation media, but in three DDLS cell lines, this induction[ncbi.nlm.nih.gov]

  • Spindle Cell Carcinoma of the Larynx

    We present two cases of SPCC of the true vocal fold that presented as a benign appearing subepithelial mass.[experts.umich.edu] The results support the hypothesis that the spindle cell carcinomas are true carcinomas with mesenchymal metaplasia and that the spindle-shaped cells are part of the neoplasm[ncbi.nlm.nih.gov] We describe a case of spindle cell carcinoma of the larynx with a verrucous carcinoma component. To our knowledge, this entity has never been documented before.[ncbi.nlm.nih.gov] The histologic pattern of this entity was mainly that of a malignant spindle cell process, but a definite squamous cell carcinoma component was evident.[ncbi.nlm.nih.gov]

  • Gliosarcoma

    Abstract A 51-year-old right-handed woman initially presented with generalized tonic-clonic seizures.[ncbi.nlm.nih.gov] A large amount of relative sparse spindle cells (sarcomatous areas) were positive for vimentin.[ncbi.nlm.nih.gov] Abstract A 49-year-old man developed a gliosarcoma with prominent osteoid components 15 months after surgical resection and postoperative radiation and chemotherapy for a[ncbi.nlm.nih.gov] Giant cell glioblastomas had LOH 10q in 50% and LOH 19q in 42% of cases.[ncbi.nlm.nih.gov]

  • Perineurioma

    Histologically, they were composed of intimately admixed plump spindle cells and elongated slender spindle cells forming storiform, lamellar or fascicular architecture.[ncbi.nlm.nih.gov] Within the myxoid stroma, occasional eosinophils were present together with a delicate capillary network.[ncbi.nlm.nih.gov] The second component exhibited the opposite immunophenotype and was consistent with a perineurioma (Fig. 1 f). The perineurial component was present in the margins.[karger.com] cell tumor/perineurioma.[e-sciencecentral.org]

  • Follicular Dendritic Cell Sarcoma

    Abstract Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm of the antigen presenting cells of the immune system.[ncbi.nlm.nih.gov] […] cell ( n 6) malignant melanoma, and spindle cell carcinoma ( n 11).[doi.org] Imaging reveals a solid mass with a cystic component and a clear boundary. In addition, the solid part exhibits poor contrast enhancement.[ncbi.nlm.nih.gov] cell sarcoma with immature T-cell proliferation require clarification.[ncbi.nlm.nih.gov]

  • Inflammatory Myofibroblastic Tumor

    An IMT usually presents as a solitary nodule but can also present as a locally invasive lesion.[ctsnet.org] The tumor has spindle cell proliferation with a prominent inflammatory infiltrate and myxoid degeneration favoring other designations such as inflammatory pseudotumor and[ncbi.nlm.nih.gov] OBJECTIVE: Carcinosarcoma is a rare malignant tumor with both carcinomatous and sarcomatous components.[ncbi.nlm.nih.gov] The dedifferentiated component of dedifferentiated liposarcoma shows wide histologic variation including tumors with heterologous differentiation.[experts.umich.edu]

  • Well-Differentiated Liposarcoma

    This is the strategy followed by the authors in a case of a 53 year old lady presenting with a large retroperitoneal lipomatous neoplasm within a sciatic hernia.[ncbi.nlm.nih.gov] There is paucity of information on head and neck subcutaneous liposarcomas of spindle cell atypical lipomatous tumor/well differentiated liposarcoma type (S-WDL/ALT).[austinpublishinggroup.com] Three cases showed high-grade osteosarcomatous transformation juxtaposed to the low-grade osteosarcomatous component, reminiscent of the "dedifferentiation" phenomenon of[ncbi.nlm.nih.gov] Both presented clinically as a skin tag. The neoplasms arose in a 56-year-old female and a 69-year-old male patient.[ncbi.nlm.nih.gov]

  • Solitary Fibrous Tumor

    Abstract We describe the case of an 81-yr-old woman who presented with bilateral pulmonary nodules in the setting of a large uterine mass, concerning for a gynecologic malignancy[ncbi.nlm.nih.gov] In this first known case report of MELTVR, the authors present a case of MELTVR that was histologically categorized in a nonmyxoid spindle-cell tumor group and resembled solitary[ncbi.nlm.nih.gov] The tumor also comprised high-grade sarcomatous components; these included lipid-rich, rhabdomyosarcomatous, and pleomorphic components.[ncbi.nlm.nih.gov] By contrast, nuclear STAT6 staining was present in three cases of giant cell angiofibroma (i.e., giant-cell rich solitary fibrous tumor), both in the spindle cell component[ncbi.nlm.nih.gov]

  • Spindle Cell Sarcoma

    Abstract This report describes a patient who presented with pancoast syndrome, secondary to spindle cell sarcoma of the lung.[ncbi.nlm.nih.gov] Spindle cell sarcoma (SCS) is a malignant neoplasm of mesenchymal origin.[symptoma.com] Final pathological examination showed a germ cell tumor of which yolk sac tumor formed the major component including a small area that appeared to be immature nerve tissue[ncbi.nlm.nih.gov] Abstract The article presents the case of a 73-year-old female injured in a bicycle accident, who was diagnosed with a left hemothorax.[ncbi.nlm.nih.gov]

  • Synovial Sarcoma

    A case of a 68-year-old male with an extensive smoking history who presented with chest pain and a primary, central, metabolically active lung mass was reported.[ncbi.nlm.nih.gov] Both spindle and epithelial cells were negative for thyroglobulin, calcitonin, synaptophysin and chromogranin.[ncbi.nlm.nih.gov] We present a case of a SS with a poorly differentiated component that resembles Ewing sarcoma (ES).[ncbi.nlm.nih.gov] To understand the molecular effects of HDAC inhibition, RNA-seq transcriptome analysis was undertaken in six human synovial sarcoma cell lines.[ncbi.nlm.nih.gov]