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  • Crystal Arthropathy

    712 Crystal arthropathies 712.1 Chondrocalcinosis due to dicalcium phosphate crystals 712.10 Chondrocalcinosis, due to dicalcium phosphate crystals, site unspecified convert[icd9data.com] From Wikipedia, the free encyclopedia Jump to navigation Jump to search Crystal arthropathy Specialty Rheumatology Crystal arthropathy is a class of joint disorder (called[en.wikipedia.org] Gout and Other Crystal Arthropathies, by Dr.[elsevier.com] Chondrocalcinosis, calcified cartilage seen on radiographs, is found in most patients with pseudogout.[musculoskeletalkey.com] Although these changes are non-specific, the finding of basic calcium phosphate crystal aggregates in all four cases and the near total absence of an inflammatory reaction[ncbi.nlm.nih.gov] Wrist involvement may result in scapholunate advanced collapse.[omicsonline.org] Other sites include the wrist, shoulder, ankle, elbow, and hands. Rarely, the temporomandibular joint and ligamentum flavum of the spinal canal are involved.[what-when-how.com] This article reviews the relevant epidemiologic data, with a focus on recent progress and data on other crystal arthropathies.[ncbi.nlm.nih.gov] Pathology The most common arthropathies are: gouty arthropathy due to monosodium urate (MSU) deposition pseudogout due to calcium pyrophosphate dihydrate (CPPD) deposition[radiopaedia.org] […] of diuretics Renal diseases Immunosuppressive therapy Obesity and associated metabolic syndrome Dietary trends Limitations of existing therapies What is the most common site[brainscape.com]

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  • Pseudogout

    […] phosphate crystals, of multiple sites Chondrocalcinosis due to dicalcium phosphate crystals, of the ankle and foot Chondrocalcinosis due to dicalcium phosphate crystals,[icd9data.com] Abstract Gout and pseudogout are inflammatory arthritides due to monosodium urate and calcium pyrophosphate dihydrate crystal formation.[ncbi.nlm.nih.gov] In fact, excessive alcohol use has many potential bad effects on the liver, heart, nerves, and other organs.[hopkinsarthritis.org] Calcium pyrophosphate deposition disease (Chondrocalcinosis, Pseudogout) References What is Calcium pyrophosphate deposition disease (Chondrocalcinosis, Pseudogout) Pseudogout[myvmc.com] To our knowledge, this is one of the few case reports of septic arthritis due to this organism, and the first in association with pseudogout.[ncbi.nlm.nih.gov] Calcium Pyrophosphate Crystal Formation Calcium pyrophosphate crystal form from the bonding of inorganic phosphate with calcium.[healthhype.com] Temporomandibular joint pseudogout: an uncommon site for a familiar condition F Goldblatt 1 , J Highton 2 , G R Kumara 3 1 Department of Rheumatology, Repatriation General[ard.bmj.com] […] side effects. 8 Strength of recommendation was graded using the EULAR 0–100 mm visual analogue scale (VAS). 9 10 All measures were reported with 95% CI unless otherwise specified[dx.doi.org] We reviewed previously reported cases of pseudogout involving the lumbar intervertebral disc and discuss the pathogenesis and treatment of the disease.[ncbi.nlm.nih.gov] NATURAL TREATMENTS FOR PSEUDOGOUT CRYSTALS Natural treatments for pseudogout crystals involves several key nutrients Although there is still no known cure for this disease[humanvitaminhealth.com]

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  • Gout

    This article summarizes the use of advanced imaging techniques in the diagnosis and assessment of gout and other crystal arthropathies.[ncbi.nlm.nih.gov] 2015 ICD-9-CM Diagnosis Code 274.8 Gout with other specified manifestations There are 3 ICD-9-CM codes below 274.8 that define this diagnosis in greater detail.[icd9data.com] Pseudogout (chondrocalcinosis) is a similar condition caused by deposits of calcium pyrophospate crystals in the joints.[britannica.com] However, it is caused by calcium phosphate, not uric acid.often, gout first attacks your big toe. It can also attack ankles, heels, knees, wrists, fingers and elbows.[icd9data.com] Among controls, 16% were found to have these abnormal ultrasound findings by both two sites and six sites examinations.[ncbi.nlm.nih.gov] Eventually other joints become involved.[symptoma.com] Chondrocalcinosis is present in 5%.[radiopaedia.org] However, it is caused by calcium phosphate, not uric acid.[medlineplus.gov] Supplements haven't been tested for safety and due to the fact that dietary supplements are largely unregulated, the content of some products may differ from what is specified[verywell.com] crystal arthropathies.[massgeneral.org]

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  • Nephrocalcinosis

    […] phosphate crystals, of multiple sites Chondrocalcinosis due to dicalcium phosphate crystals, of the ankle and foot Chondrocalcinosis due to dicalcium phosphate crystals,[icd9data.com] The major finding was that, in addition to a causal role in initiating renal crystal retention, the tubular epithelium also is involved in an active crystal clearing mechanism[uantwerpen.be] Histopathological confirmation could not be done due to bilateral severely contracted kidneys.[ncbi.nlm.nih.gov] In vitro studies showed that the p.Arg495His mutation resulted in decreased phosphate uptake when compared to wild-type SLC34A1.[ncbi.nlm.nih.gov] […] mutation which changes intron 4 consensus splice site from 'GT' to 'TT' resulting in decreased splice efficiency and the formation of a truncated protein with loss of 64[ncbi.nlm.nih.gov] 2018 2019 Billable/Specific Code calcium E83.50 ICD-10-CM Diagnosis Code E83.50 Unspecified disorder of calcium metabolism 2016 2017 2018 2019 Billable/Specific Code other specified[icd10data.com] Nephrocalcinosis involves the deposition of microscopic crystals in the tubular lumen or interstitium.[ncbi.nlm.nih.gov] Kidney stones are a well known complication of high blood calcium due to primary hyperparathyroidism.[blog.parathyroid.com] The coding sequence and splice sites of candidate genes (CYP24A1, CYP27B1, FGF23, KLOTHO, SLC34A3 and SLC34A1) were sequenced directly.[ncbi.nlm.nih.gov] In this study, we wanted to elucidate whether the histopathological appearance of calcium phosphate deposits provides information about possible etiology.[ncbi.nlm.nih.gov]

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  • Hypophosphatasia

    Abstract In adults, hypophosphatasia (HPP) may be revealed by fractures, mainly metatarsal and femoral, and by crystal-related joint diseases.[ncbi.nlm.nih.gov] […] mutations (as many as 260 genetic mutations have been associated with HPP), patients have disordered bone mineralization leading to rickets, osteomalacia, fractures and other[ncbi.nlm.nih.gov] The build-up of inorganic pyrophosphate promotes the development of articular chondrocalcinosis.[ncbi.nlm.nih.gov] Abstract Hypophosphatasia is an inherited disorder due to mutations in the bone alkaline phosphatase (ALPL) gene.[ncbi.nlm.nih.gov] Treatment with high-dose pyridoxal phosphate eliminated his seizures.[ncbi.nlm.nih.gov] […] domains such as the active site, the vicinity of the active site and homodimer interface.[ncbi.nlm.nih.gov] We assessed the pharmacodynamics, pharmacokinetics, preliminary efficacy, and safety of BPS804 administrations at specified intervals during treatment and follow-up.[ncbi.nlm.nih.gov] The gene encodes alkaline phosphatase, tissue-nonspecific isozyme (TNSALP) involved in skeletal mineralization.[orpha.net] In HPP, extracellular accumulation of inorganic pyrophosphate, a TNSALP substrate, inhibits hydroxyapatite crystal growth leading to rickets or osteomalacia.[ncbi.nlm.nih.gov] In adults, main clinical involvement includes early loss of primary or secondary teeth, osteoporosis, bone pain, chondrocalcinosis, and fractures.[ncbi.nlm.nih.gov]

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  • Calcium Pyrophosphate Arthropathy

    Gout and Other Crystal Arthropathies, by Dr.[books.google.de] Calcium pyrophosphate and pseudogout. Arthroscopy; 1985;1(1):8-16. INTERNET Chondrocalcinosis 2. Genetic and Rare Diseases Information Center. Last updated: 1/12/2018.[rarediseases.org] […] acute, self-limiting synovitis with CPPD Osteoarthritis with CPPD (formerly pseudo-osteoarthritis) – CPPD that occurs in a joint that has pre-existing degenerative changes due[bpac.org.nz] McCarty D et al . (1983) Crystal populations in human synovial fluid: identification of apatite, octacalcium phosphate, and tricalcium phosphate .[nature.com] […] musculoskeletal system and connective tissue › M05-M1A Inflammatory polyarthropathies › M11- Other crystal arthropathies › Other specified crystal arthropathies, unspecified site[icd10data.com] Symptomatic involvement of the spine by calcium pyrophosphate deposition disease is rare except by nodular deposition in the ligamentum flavum and atlanto-occipital ligament[ncbi.nlm.nih.gov] The knee is the most commonly involved joint. Ankle, wrist, and shoulder involvement is also common, and acromioclavicular pseudogout has been described.[musculoskeletalkey.com] Tophaceuos Calcium Pyrophosphate Dihydrate Deposition Disease of the Temporomandibular Joint: The Preferential Site?.[cambridge.org] The crystals are usually detected by imaging and/or joint fluid analysis.[en.wikipedia.org] […] and the phosphate radical; dibasic and tribasic calcium phosphate are used as sources of calcium. calcium polycarbophil a hydrophilic agent used as a bulk laxative . calcium[medical-dictionary.thefreedictionary.com]

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  • Familial Calcium Pyrophosphate Deposition

    Gout and Other Crystal Arthropathies, by Dr.[books.google.com] Calcium pyrophosphate and pseudogout. Arthroscopy; 1985;1(1):8-16. INTERNET Chondrocalcinosis 2. Genetic and Rare Diseases Information Center. Last updated: 1/12/2018.[rarediseases.org] In another kindred with CPPDD due to precocious osteoarthritis, the phenotype was linked to markers of chromosome 8p.[ncbi.nlm.nih.gov] Reginato AJ, Knowlton RG, Jimenez SA, et al. : Calcium pyro-phosphate disease in the Chiloe islanders.[link.springer.com] Diseases of the musculoskeletal system and connective tissue › M05-M1A Inflammatory polyarthropathies › M11- Other crystal arthropathies › Other chondrocalcinosis, unspecified site[icd10data.com] ., marked suprapatellar pouch enlargement due to abnormal amounts of intraarticular synovial fluid), large, rounded hyperechoic deposits in the menisci, and confluent deposits[jrheum.org] It is more commonly known by alternative names that specify certain clinical or radiographic findings, although neither is synonymous with CPPD.[wikidoc.org] NATURAL TREATMENTS FOR PSEUDOGOUT CRYSTALS Natural treatments for pseudogout crystals involves several key nutrients Although there is still no known cure for this disease[humanvitaminhealth.com] […] and the phosphate radical; dibasic and tribasic calcium phosphate are used as sources of calcium. calcium polycarbophil a hydrophilic agent used as a bulk laxative. calcium[medical-dictionary.thefreedictionary.com] The ANKH protein is involved in pyrophosphate metabolism and, more specifically, in pyrophosphate transport from the intracellular to the extracellular compartment.[ncbi.nlm.nih.gov]

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  • Gouty Arthritis

    RESULTS: The overall rate of detection of MSU crystals was 78.8%.[ncbi.nlm.nih.gov] 2015 ICD-9-CM Diagnosis Code 274.8 Gout with other specified manifestations There are 3 ICD-9-CM codes below 274.8 that define this diagnosis in greater detail.[icd9data.com] […] periarticular demineralization o Erosion of joint margins with sclerosis o Cartilage destruction late in course of disease o Periarticular swelling (in acute monarticular gout) o Chondrocalcinosis[learningradiology.com] Fractional excretion of phosphate was low (5.3%) and fractional free water clearance per fractional distal sodium delivery was 0.51.[ncbi.nlm.nih.gov] […] arthroscopic examination revealed abundant calcific material deposited around the knee joint, including in the ACL tissue, and that the ACL was torn at the femoral attachment site[ncbi.nlm.nih.gov] Abstract Previous studies demonstrated that toll-like receptor (TLR) 4 was involved in the development of autoinflammatory disease including gouty arthritis (GA).[ncbi.nlm.nih.gov] Pseudogout (chondrocalcinosis) is a similar condition caused by deposits of calcium pyrophospate crystals in the joints.[britannica.com] However, it is caused by calcium phosphate, not uric acid.[fpnotebook.com] Gout is a metabolic disorder related to excess of uric acid in the extracellular compartment, and deposition of monosodium urate crystals in the joints and other sites.[ncbi.nlm.nih.gov] The mean (SD) total dose of colchicine given was not specified.[doi.org]

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  • Osteomalacia

    Kaartinen and Faleh Tamimi , Bone Extracts Immunomodulate and Enhance the Regenerative Performance of Dicalcium Phosphates Bioceramics , Acta Biomaterialia , 10.1016/j.actbio[doi.org] When concentrations are too low crystallization does not proceed normally.[wikilectures.eu] […] edit Wikibooks (0 entries) edit Wikiquote (0 entries) edit Wikisource (0 entries) edit Wikiversity (0 entries) edit Wikivoyage (0 entries) edit Wiktionary (0 entries) edit Other[wikidata.org] Patients also suffer from arthritis and chondrocalcinosis, as well as dental abnormalities. Lowering phosphate intake could reduce pyrophosphate levels.[163.178.103.176] Abstract Ferric carboxymaltose (FCM) is a novel iron formulation increasingly prescribed due to its effectiveness and fast infusion time.[ncbi.nlm.nih.gov] He had multiple stress fractures, low serum phosphate, decreased renal tubular reabsorption of phosphate, and normal PTH and FGF23, indicating adult onset hypophosphatemic[ncbi.nlm.nih.gov] It's very important that you take the correct dosage of supplements as specified by your GP.[hypopara.org.uk] […] mater and involving the skull.[ncbi.nlm.nih.gov] […] clinicians need to be aware that TDF can cause proximal renal tubular dysfunction and loss of bone mineral density, especially in patients with concomitant renal disease or other[ncbi.nlm.nih.gov] Patients also suffer from arthritis and chondrocalcinosis, as well as dental abnormalities.[courses.washington.edu]

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  • Hereditary Chondrocalcinosis

    Idiopathic by far the most common Pathology Chondrocalcinosis is the finding of radioopaque crystals in hyaline cartilage & can be salts of Calcium pyrophosphate dihydrate Dicalcium[orthofracs.com] ; may have histiocytic and giant cell reaction around these crystals CPPD crystals have rhomboid or parallelelipedic morphology Microscopic (histologic) images Images hosted[pathologyoutlines.com] Other sites include the wrist, shoulder, ankle, elbow, and hands. Rarely, the temporomandibular joint and ligamentum flavum of the spinal canal are involved.[what-when-how.com] Abstract A clinical and radiological survey of 77 members of a Tunisian family with hereditary chondrocalcinosis was performed.[ncbi.nlm.nih.gov] Chondrocalcinosis 2 (CCAL2) occurs due to mutations in the ANKH gene.[cags.org.ae] The theory outlined in these papers is important for understanding CPPD crystal deposition and basic phosphate crystal formation and dissolution.[journals.lww.com] Imaging of chondrocalcinosis: Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease - imaging of common sites of involvement.[moh-it.pure.elsevier.com] Reginato AJ, Knowlton RG, Jimenez SA, et al. : Calcium pyro-phosphate disease in the Chiloe islanders.[link.springer.com] Thus, the radiologist plays an important role in confirming these diabetic complications, furthermore he is involved in the therapeutic management of the patient.[books.google.com] […] familial study of three patients from the Osona region (Barcelona) with early onset (fourth decade) of articular chondrocalcinosis (CCA) disclosed the occurrence of CCA in other[biomedsearch.com]

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