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4,627 Possible Causes for Core, Cytochrome, II, Protein,, Reductase, Ubiquinol, c

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  • Arginine

    KEYWORDS: CYP2J2; docking; homology modeling; human cytochrome P450; inhibitor; mutants; regioselectivity[ncbi.nlm.nih.gov] II against cancer.[ncbi.nlm.nih.gov] If you’re not already getting a wholesome animal source of omega-3 fatty acids and taking a high-quality CoQ10 or Ubiquinol , then my Cardiac Support Pack may be the ideal[products.mercola.com] The targeting of GBP1 to cytosolic bacteria, via a unique triple-arginine motif present in its C terminus, promotes the corecruitment of four additional GBP paralogs (GBP2[ncbi.nlm.nih.gov] KEYWORDS: PRMT5; cancer; chromatin; epigenetics; histone methylation; post-translational modification; protein methylation[ncbi.nlm.nih.gov] RESULTS: The molecular modeling result showed that GA could encapsulated stably in the core of OACS micelles.[ncbi.nlm.nih.gov] […] and functional studies of fibroblast mitochondria show that P5CS deficiency is not associated with the mitochondrial alterations observed in Δ(1)-pyrroline-5-carboxylate reductase[ncbi.nlm.nih.gov]

  • Brucella Suis

    Abstract Expression of the high-oxygen-affinity cytochrome cbb3 and cytochrome bd ubiquinol oxidases of Brucella suis was studied in vitro and in the intramacrophagic niche[ncbi.nlm.nih.gov] The acetylated derivatives were generally better bsCA II inhibitors compared to the corresponding deacetylated compounds.[ncbi.nlm.nih.gov] The mutant complemented by b-clpA and overexpressing the gene was even more impaired at 37 and 42 degrees C.[ncbi.nlm.nih.gov] The purified recombinant proteins were examined for their binding activity with antiserum.[ncbi.nlm.nih.gov] The periplasmic core complex of VirB8/VirB10 structurally and functionally links the cytoplasmic NTPases of the system with its outer membrane and pilus components.[ncbi.nlm.nih.gov] Some of these sulphonamides were most effective bacterial CA than human (h) CA I and II inhibitors, making them selective for the prokaryotic enzymes.[ncbi.nlm.nih.gov] In this paper, we describe the synthesis of a family of oxo- and thioxo-imidazo[1,5-c]pyrimidines, potential enzyme inhibitors.[ncbi.nlm.nih.gov]

    Missing: Reductase
  • Moraxella Catarrhalis

    […] bc1 complex respiratory unit [PATH: mct00190 ] M00153 Cytochrome bd ubiquinol oxidase [PATH: mct00190 ] M00156 Cytochrome c oxidase, cbb3-type [PATH: mct00190 ] M00157 F-type[kegg.jp] The protein encoded by ORF113 was predicted to have a signal peptidase II cleavage site, and globomycin inhibition experiments confirmed that this protein was indeed a lipoprotein[ncbi.nlm.nih.gov] Slevogt H, Schmeck B, Jonatat C, et al.[erj.ersjournals.com] KEYWORDS: ABC transporter protein; Chronic obstructive pulmonary disease; Moraxella catarrhalis; Otitis media; Substrate binding protein; Vaccine[ncbi.nlm.nih.gov] ISSN: 0950-2688 EISSN: 1469-4409 URL: /core/journals/epidemiology-and-infection[cambridge.org] In all five mutants, expression of nitrate reductase genes was increased and of nitrite reductase decreased, suggesting an impaired aerobic respiration.[ncbi.nlm.nih.gov] We studied: (i) neuropeptide-mediated direct antibacterial activity exerted against Moraxella catarrhalis and nontypeable Haemophilus influenzae, and (ii) indirect immunomodulatory[ncbi.nlm.nih.gov]

  • Microcephaly

    We report a novel homozygous missense mutation in the ubiquinol-cytochrome c reductase synthesis-like (BCS1L) gene in two consanguineous Turkish families associated with deafness[ncbi.nlm.nih.gov] Author information 1 Dipartimento di Medicina Molecolare e Biotecnologie Mediche DMMBM, Università di Napoli Federico II, Via Sergio Pansini 5, Naples, 80131, Italy. 2 CEINGE[ncbi.nlm.nih.gov] Exome sequencing identified a known pathogenic homozygous alteration in DEAF1, c.676C T (p.R226W), in this patient.[ncbi.nlm.nih.gov] […] interference combined with auxin-inducible degron, we show that ASPM functions in spindle pole organisation during mitotic metaphase redundantly with another microcephaly protein[ncbi.nlm.nih.gov] RESULTS: We identified six individuals from three unrelated families with a founder homozygous splice mutation in TRAPPC6B , encoding a core subunit of the complex TRAPP I[ncbi.nlm.nih.gov] Whole exome and Sanger sequencing identified two novel missense mutations, c.28G T and c.189G T, in the WDR62 gene.[ncbi.nlm.nih.gov] The core of the complex consists of four subunits: SMC1A, SMC3, RAD21, and STAG1/2.[ncbi.nlm.nih.gov]

  • Pancytopenia

    […] constructed the K562 cDNA library, which we used to screen seven candidate autoantigens expressed in haematopoietic cells of IRP: ferritin, light polypeptide, ubiquinol-cytochrome[ncbi.nlm.nih.gov] Twenty candidate mRNAs and nine miRNAs were selected for validation in stage II (qRT-PCR).[ncbi.nlm.nih.gov] CONCLUSION: Anti-C(w) may lead to severe fetal anemia and consecutive complications.[ncbi.nlm.nih.gov] Neither the GTPase activity of the mutant proteins nor its activation by the SDBD protein or the 60S ribosomal subunit were affected.[ncbi.nlm.nih.gov] M BEVERIDGE, MBBS MRCP, Core Medical Trainee Year 2, Department of Haematology, Addenbrookes Hospital, Cambridge.[bjmp.org] […] pancytopenia resulting from maintenance chemotherapy in a patient with acute promyelocytic leukemia and two pharmacogenetic mutations, namely, methylene tetrahydrofolate reductase[ncbi.nlm.nih.gov] Contrast enhanced computed tomography of the abdomen showed findings consistent with grade II splenic injury.[bmcsurg.biomedcentral.com]

  • Growth Retardation

    We report a novel homozygous missense mutation in the ubiquinol-cytochrome c reductase synthesis-like (BCS1L) gene in two consanguineous Turkish families associated with deafness[ncbi.nlm.nih.gov] )(morpholine)Cl C1a-C3a, Pt(II)(salicylaldimine) (methylpiperazine)Cl C1b-C3b, di-metallic Pt(II) 2 (bis-salicylaldimine)(morpholine) 2 Cl 2 C4a and Pt(II) 2 (bis-salicylaldimine[ncbi.nlm.nih.gov] KEYWORDS: C-type natriuretic peptide (CNP); Glucocorticoid; Growth retardation; Skeletal growth[ncbi.nlm.nih.gov] We present a three-month-old girl with hypoproteinemia, growth retardation, and generalized stiff and edematous skin, who was diagnosed as protein-losing enteropathy.[ncbi.nlm.nih.gov] Critical Essential Core Tested Community How important is this topic for clinical practice?[step2.medbullets.com] This was associated with activation of caspase-9 and cytochrome C release.[ncbi.nlm.nih.gov] Figure 2 Comparison of infants discharged from level I–II units.[fn.bmj.com]

  • Oligospermia

    The mRNA and protein expression levels of apoptosis-associated genes [Bcl‑2, Bax, cytochrome c (Cyt C) and caspase-3] were measured by quantitative polymerase chain reaction[ncbi.nlm.nih.gov] In oligospermic patients two groups were identified: I. those with normal spermatogenesis (4), and II. those with subnormal spermatogenesis (19).[ncbi.nlm.nih.gov] Fluorescence polarization studies revealed weaker hydrophobicity around these sperm proteins in oligospermia.[ncbi.nlm.nih.gov] Total abstract views: 0 * Loading metrics... * Views captured on Cambridge Core between . This data will be updated every 24 hours.[journals.cambridge.org] OBJECTIVE: This study was designed to test the hypothesis that mutations in the gene for type 2 steroid 5alpha-reductase (SRD5A2) may be the cause of a phenotype characterized[ncbi.nlm.nih.gov] It also potently inhibits other normal cellular tyrosine kinases, c-abl, c-arg, and the receptors for platelet-derived growth factor (PDGF) and stem-cell factor (c-kit).[nejm.org] If this occurs, he may choose to stop the medication or consider the use of a 5-alpha reductase inhibitor to counteract these effects.[godot.urol.uic.edu]

    Missing: Ubiquinol
  • Dimethyl Sulfoxide

    Various exogenous compounds, for example, the drugs bupropione and propofol, but also various cytostatics, are metabolized in the liver by the enzyme cytochrome P450 (P450[ncbi.nlm.nih.gov] Complex formation of nickel( II ) with dimethyl sulfoxide, methanol, and acetonitrile in a TFSA -based ionic liquid of [C 2 mim][TFSA] Author affiliations * Corresponding[pubs.rsc.org] […] was only induced when HFMSCs were treated in the following conditions: in high-dose combination (5-aza 50 μM RA 10(-1) μM DMSO 1 %) in cardiac differentiation medium at 37 C[ncbi.nlm.nih.gov] […] are determined jointly by relative exposure of polar and nonpolar residues of a protein and the mode of molecular action of a solvent on that protein.[ncbi.nlm.nih.gov] Till date, there have been no studies to directly identify the residues involved in the core of the assembly.[ncbi.nlm.nih.gov] DMSO reductase serves as the terminal reductase under anaerobic conditions, with DMSO being the terminal electron acceptor.[uniprot.org] EG did not exert direct genotoxic activity, however EG exhibited significant genotoxic and clastogenic activities in the presence of an external cytochrome-based P450 oxidation[ncbi.nlm.nih.gov]

    Missing: Ubiquinol
  • Novobiocin

    NB induces cytosolic accumulation of cytochrome c and activation of caspase-9 and caspase-3, triggering apoptosis of HL-60/Bcr-Abl and K562 cells.[ncbi.nlm.nih.gov] […] novobiocin-elicited proteolysis of Topo II and the PMA-induced Topo II phosphorylation, as well as the decrease in Topo II activity and the acquisition of differentiation[ncbi.nlm.nih.gov] Recent studies of structure-activity relationship (SAR) by Renoir and co-workers highlighted the crucial role of the C-4 and/or C-7 positions of the coumarin and removal of[ncbi.nlm.nih.gov] BACKGROUND: Heat shock protein 90 (Hsp90) interacts with and stabilizes several oncogenic protein kinases (e.g., p185(erbB2), p60(v-src), and Raf-1) and is required for the[ncbi.nlm.nih.gov] Herein, 24 cores were synthesized with varying distances and angles between the sugar and amide moieties.[ncbi.nlm.nih.gov] […] technique for measuring pyrimidine dimer frequencies in genomic restriction fragments, we have determined the extent of DNA repair in the active, essential dihydrofolate reductase[ncbi.nlm.nih.gov] "Coumarin formation in novobiocin biosynthesis: beta-hydroxylation of the aminoacyl enzyme tyrosyl-S-NovH by a cytochrome P450 NovI".[en.wikipedia.org]

    Missing: Ubiquinol
  • Pili Torti

    Symbol Name BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like CDH3 cadherin 3, type 1, P-cadherin (placental) DSG4 desmoglein 4 FOXE1 forkhead box E1 HR hair growth[amp.pharm.mssm.edu] In this X-linked recessive disorder, the defective gene, MKN or ATP7A, which maps to Xq13.3, encodes a copper-translocating membrane protein adenosine triphosphatase that[dermaamin.com] Get full exposure to core knowledge with coverage of dermatology’s entire spectrum of subspecialties.[books.google.de] Figure 7 Scanning electron microscope picture of hair from II.1 showing pili torti et canaliculi.[jmg.bmj.com] Characterization of the Menkes protein copper-binding domains and their role in copper-induced protein relocalization. Hum Mol Genet . 1999 Aug. 8(8):1473-8. [Medline] .[emedicine.medscape.com] Schachner, MD Harvey Blank Professor and Chairman, Dermatology & Cutaneous Surgery University of Miami Miller School of Medicine Miami, FL Ronald C.[books.google.de] Chavanas S, Garner C, Bodsemer C, Ali M, Teillac DH, Wilkinson J, et al .[ijtrichology.com]