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985 Possible Causes for Cysteine, Proteinases

  • Urinary Tract Infection

    […] uropathogenic Escherichia coli Yu Gu , Yue Xu , Jing Xu , Xinyan Yu , Xu Huang , Genyan Liu & Xiaoqiu Liu Applied Microbiology and Biotechnology (2019) Effect of Subtilisin-like Proteinase[doi.org] Inhibitory effect of cranberry polyphenol on biofilm formation and cysteine proteases of Porphyromonas gingivalis.[doi.org]

  • Streptococcal Infection

    […] digests host connective tissue, hyaluronic acid, and the organism's own capsule), streptokinases (proteolytic), and streptodornase A-D (deoxyribonuclease activity). [13] Proteinase[emedicine.medscape.com] Cysteine protease (Exotoxin B) Pyoderma strains of S. pyogenes can colonize or survive on normal skin surfaces for extended periods.[atsu.edu] Exotoxins (for example, DNAses A, C and D, streptolysin S, proteinase, streptokinase, and pyrogenic exotoxins [A-D]) Human immune system stimulators (for example, streptolysin[medicinenet.com]

  • Porphyromonas Gingivalis

    As sPAD can influence microbial virulence, this study was designed to evaluate the effect of sPAD on gene expression level of arginine A-specific cysteine proteinase (rgpA[ncbi.nlm.nih.gov] These receptors include proteinase-activated receptors that are activated by P. gingivalis - derived proteinases [29] .[doi.org] Endopeptidases/chemistry Cysteine Endopeptidases/immunology* Disease Models, Animal Female Humans Immunization Immunoglobulin M/biosynthesis* Immunoglobulin M/metabolism[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    Saliva sample (100 μL) was digested overnight with proteinase K (PK) at 55 C in a 96-well plate (8-10 wells per subject per time point).[doi.org] Each of these compact units contains conserved residues including four cysteines and a nearly invariant tryptophan.[dx.doi.org] After DNase I heat inactivation (10 min at 70 C), supernatants were mixed (1:1 [vol/vol]) with lysis buffer (0.1 mg of proteinase K/ml in water) and incubated for 60 min at[dx.doi.org]

  • Malignant Neoplasm

    […] epithelial cells (HMEC), MMP-7 can bind to several glycosylation branches of the CD44 receptor isoform variant-3 (CD44v3) which can colocalize with MMP-7 and anchor this proteinase[doi.org] A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors . Proc. Natl Acad. Sci. USA 94 , 2859–2863 (1997). 76.[doi.org] Proteinase K, at a final concentration of 20 μg/ml, was added and the mixture was incubated at 55 C overnight.[doi.org]

  • Trichomonas Vaginalis

    The CP30 band is a cysteine proteinase because its activity was inhibited by E-64, a thiol proteinase inhibitor.[doi.org] This review focuses on the advancements reached in the area of the pathogenesis of T. vaginalis, especially in the role of the cysteine proteinases.[ncbi.nlm.nih.gov] Key words: Trichomonas vaginalis / Trichomonosis / Cysteine proteinases / Pathogenesis H.M.[doi.org]

  • HIV-proteinase Inhibitor

    In vitro resistance to an inhibitor of HIV proteinase (Ro 31–8959) relative to inhibitors of reverse transcriptase (AZT and TIRO).[link.springer.com] It contains inhibitors of multiple cysteine and serine protease families.[en.wikipedia.org] Abstract Newly developed substrate analogue peptidomimetics are able to inhibit the human immunodeficiency virus, HIV-1 proteinase at nanomolar concentration.[ncbi.nlm.nih.gov]

  • Tuberculosis

    An enzyme-linked immunosorbent assay was performed for anti-myeloperoxidase (MPO) and anti-proteinase 3 (PR3) detection.[ncbi.nlm.nih.gov] […] either to be directly tested with microscopy and the Xpert MTB/RIF assay (one sample) or to be processed by standard decontamination with sodium hydroxide and N -acetyl-cysteine[doi.org] This material was also subjected to proteinase K digestion as indicated above.[dx.doi.org]

  • Trichobilharzia Regenti

    J Chem Ecol 14:691–700 CrossRef Google Scholar Dalton JP, Clough KA, Jones MK, Brindley PJ (1997) The cysteine proteinases of Schistosoma mansoni cercariae.[doi.org] Cysteine peptidases of 33 kDa and 33-34 kDa were identified in extracts of T. regenti and S. mansoni cercariae employing a biotinylated Clan CA cysteine peptidase-specific[ncbi.nlm.nih.gov] Characterization of the cathepsin-like cysteine proteinases of Schistosoma mansoni . Infection and Immunity 64 , 1328 – 1334 . Dalton , J. P. , Clough , K.[doi.org]

  • Entamoeba Histolytica

    The cysteine proteinase-adhesin complex of this parasite (EhCPADH) is a heterodimeric protein formed by a cysteine protease (EhCP112) and an adhesin (EhADH) that plays an[ncbi.nlm.nih.gov] Macrophage cytoskeletal cleavages were dependent on Eh cysteine proteinases EhCP-A1 and EhCP-A4 but not EhCP-A5 based on pharmacological blockade of Eh enzyme inhibitors and[ncbi.nlm.nih.gov] In this study, we have identified the key virulence factor in live Eh that elicits the fast release of mucin by goblets cells as cysteine protease 5 (EhCP5) whereas, modest[ncbi.nlm.nih.gov]

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