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  • Idiopathic Pulmonary Fibrosis

    […] and treatment to relieve your symptoms.[nhs.uk] CONCLUSIONS: We identified a LysoPC by UHPLC-HRMS as potential biomarker in serum of patients with IPF.[ncbi.nlm.nih.gov] Electronic address: [email protected][ncbi.nlm.nih.gov] In this Review, we discuss current and emerging therapies for IPF, particularly those targeting age-related mechanisms, and discuss future therapeutic approaches.[ncbi.nlm.nih.gov] A cut-off level of 30% for lymphocytes in BAL demonstrated a favorable discriminative power for the diagnosis of IPF.[ncbi.nlm.nih.gov] Subjects were randomized in a 1:1 ratio to warfarin or matching placebo for a planned treatment period of 48 weeks.[ncbi.nlm.nih.gov] pulmonary rehabilitation have been shown.[patient.info] We investigated the predictive power of the selected biomarkers to identify individuals with IPF who were at risk of progression or death.[ncbi.nlm.nih.gov] The risk of pulmonary nocardiosis may be increased in cases of IPF on immunosuppressive therapy.[ncbi.nlm.nih.gov]

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  • Dementia

    The atypical antipsychotics risperidone and olanzepine have significant efficacy for the treatment of aggression and risperidone is also efficacious in the treatment of psychosis[ncbi.nlm.nih.gov] This has been identified as an area of need in recent UK. Government reports and by the Alzheimer's Society (UK).[ncbi.nlm.nih.gov] But there is hope: if we can harness big data we may be able to address the gaps in our knowledge around treatment and care.[doi.org] Validation therapy has attracted a good deal of criticism from researchers who dispute the evidence for some of the beliefs and values of validation therapy, and the appropriateness[ncbi.nlm.nih.gov] Brain blood flow SPECT is useful in the diagnosis and differential diagnosis of the dementias.[ncbi.nlm.nih.gov] On Tuesday, that plan got a new push.[nytimes.com] Specifically, cholinesterase inhibitor use was not significantly associated with either subsequent hospitalization for pulmonary embolism (HR, 0.97; 95% CI, 0.55-1.72) or[doi.org] We found no convincing evidence for the efficacy of omega-3 PUFA supplements in the treatment of mild to moderate AD.[ncbi.nlm.nih.gov] The plan recognizes the need to address dementia from the stages of prevention of risk factors and early detection, to diagnosis and patient care, and through assurance of[brookdale.jdc.org.il]

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  • Pneumonia

    CONCLUSIONS: This case reveals an association between eribulin treatment and interstitial pneumonia.[ncbi.nlm.nih.gov] Key Points Question What is the accuracy of symptoms and physical examination findings in identifying children with pneumonia?[doi.org] We also address the types of pneumonia caused by hantaviruses, metapneumoviruses and rhinoviruses. [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov] Oxygen therapy is widely used in the treatment of lung diseases. However, the effectiveness of oxygen therapy as a treatment for pneumonia is not well known.[ncbi.nlm.nih.gov] Lim , consultant in general and respiratory medicine 1 Department of Respiratory Medicine, Nottingham City Hospital, Nottingham NG5 1PB Correspondence to: Z Hoare Prompt diagnosis[bmj.com] Unit of analysis issues Cluster‐RCTs We had planned to include cluster‐RCTs in the analysis.[doi.org] Severe pneumonia significantly impairs pulmonary function and makes long radiological sequelae in MERS. KEYWORDS: Complication; Coronavirus; MERS; Outbreak[ncbi.nlm.nih.gov] The International HIV-associated Opportunistic Pneumonias (IHOP) study was established to address these knowledge gaps.[ncbi.nlm.nih.gov] Electronic address: [email protected] 2 Department of Medicine, University of British Columbia, Vancouver, Canada. 3 Department of Radiology, University of British[ncbi.nlm.nih.gov]

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  • Tuberculosis

    With regard to treatment, we focus on important changes in the philosophy of treatment, emphasizing the responsibility of the provider to assure successful completion of treatment[dx.doi.org] RD9 profiles without RD1- identify M. tuberculosis; an additional RD4 profile per se identifies M. africanum; an additional RD4- profile per se identifies Mycobaterium bovis[ncbi.nlm.nih.gov] To evaluate DOT compared to self-administered therapy in people on treatment for active TB or on prophylaxis to prevent active disease.[ncbi.nlm.nih.gov] The Global Plan to End TB The Global Plan to End TB provides a roadmap for the fight against TB for a five-year period.[stoptb.org] TB; Tuberculosis - pulmonary; Mycobacterium - pulmonary Fitzgerald DW, Sterling TR, Haas DW. Mycobacterium tuberculosis. In: Bennett JE, Dolan R, Blaser MJ, eds.[medlineplus.gov] […] recent years, the pipeline remains thin and major challenges remain to be addressed in efficiently evaluating newer drugs to improve treatment outcomes, shorten duration of therapy[doi.org] The dangerous contact time is before treatment. However, once treatment with drugs starts, the sick person is noncontagious within a few weeks.[emedicinehealth.com] Identifying predictors of drug resistance and working on them is the important way of reducing the expansion in high burden countries.[ncbi.nlm.nih.gov] The diagnosis of TB must be confirmed by detecting the causative agent ( Mycobacterium tuberculosis , MTB) in an appropriate biological specimen.[ncbi.nlm.nih.gov]

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  • Acute Bronchitis

    Their use should be weighed against the cost and potential adverse effects for treatment of a self-limiting disease.[ncbi.nlm.nih.gov] With multiplex PCR testing, viruses were identified in 36.1% (105/291), most commonly rhinovirus (25.8%) and coronavirus (3.8%).[ncbi.nlm.nih.gov] Address reprint requests to Dr. Wenzel at the Department of Internal Medicine, Virginia Commonwealth University, 1101 E. Broad St., P.O.[doi.org] Therapy consists of both nonpharmacological and pharmacological options to include antibiotics and antivirals, antitussive agents, protussive agents, and beta-2-agonists.[ncbi.nlm.nih.gov] Abstract Cough is the most common symptom bringing patients to the primary care physician's office, and acute bronchitis is usually the diagnosis in these patients.[ncbi.nlm.nih.gov] […] that report HEDIS results to NCQA. 13,000 Recognized patient-centered medical homes. 1,200 Health plans accredited through Health Plan Accreditation. 350 Full-time employees[ncqa.org] Differentiation of cough-variant asthma may require pulmonary function testing.[merckmanuals.com] Treatment Treatment of acute bronchitis is typically divided into two categories: antibiotic therapy and symptom management.[aafp.org] CONCLUSIONS: Future efforts to reduce antibiotic prescribing should address multi-level barriers identified by clinicians and tailor strategies to differences at individual[ncbi.nlm.nih.gov]

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  • Pulmonary Hypertension

    Treatment of atrial flutter proved to be more successful than treatment of atrial fibrillation.[doi.org] METHODS: Patients with suspected pulmonary hypertension who underwent CTPA, MRI and RHC were identified.[ncbi.nlm.nih.gov] Electronic address: [email protected][ncbi.nlm.nih.gov] Importantly, 53% of patients were on background therapy with bosentan.[doi.org] Right heart catheterization remains essential for a diagnosis of PH or PAH.[ncbi.nlm.nih.gov] plans are in place and to answer any other questions you may have.[choa.org] Chronic thromboembolic pulmonary hypertension and other pulmonary artery obstructions.[patient.info] Cluster analysis of 200 patients identified four homogenous phenotypes.[ncbi.nlm.nih.gov] Thus, limited treatment data exist for the less-studied non-PAH forms of PH.[ncbi.nlm.nih.gov]

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  • Cardiac Sarcoidosis

    Sarcoidosis is typically a benign condition that does not require treatment.[heart.templehealth.org] ClinicalTrials.gov Identifier: NCT01729169 Recruitment Status : Completed First Posted : November 20, 2012 Last Update Posted : May 11, 2016 Sponsor: Information provided[clinicaltrials.gov] Baughman and Marcel Veltkamp Abstract Author Information Authors Article Metrics Metrics To address the current recommendations for screening, diagnosis , and treatment of[journals.lww.com] […] require therapy.[mayoclinic.pure.elsevier.com] Diagnosis and treatment of cardiac sarcoidosis Kengo F Kusano 1 , Kazuhiro Satomi 1 , 2 1 Department of Cardiovascular Medicine , National Cerebral and Cardiovascular Center[heart.bmj.com] Therapy and Follow-up : Severe cardiac sarcoidosis with only minor lung involvement was diagnosed and steroid therapy started with a plan to reevaluate the patient in 2-3[scmr.org] Owing to a low index of suspicion, and in some cases lack of pulmonary involvement, it may take many years before the diagnosis is finally made.[bcmj.org] 52 Issue : 4 Page : 566-567 Cardiac sarcoidosis causing sudden death Department of Pathology, J N Medical College, Belgaum, Karnataka, India Click here for correspondence address[ijpmonline.org] If there has been a response, the prednisone dose should be tapered to 5 to 15 mg/day, with treatment planned for an additional 9 to 12 months (36) .[onlinejacc.org]

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  • Radiation Pneumonitis

    Abstract The basis of radiation recall reactions (RRR) is a subclinical radiation damage that is uncovered later by treatment with anticancer agents.[ncbi.nlm.nih.gov] PURPOSE: To identify dosimetric factors that predict development of radiation pneumonitis (RP) following stereotactic or hypofractionated radiotherapy for lung tumors.[ncbi.nlm.nih.gov] Electronic address: [email protected][ncbi.nlm.nih.gov] Radiation therapy was performed at a dose of 75 Gy in 50 fractions over five weeks.[ncbi.nlm.nih.gov] RESULTS: RP was identified in 19 of 55 patients, with a median time to diagnosis of 56 days after RT.[ncbi.nlm.nih.gov] All imaging data were incorporated into a 3D planning system to evaluate correlations between RP dosimetric parameters (where fV20 is the percentage of functional lung volume[ncbi.nlm.nih.gov] Normal pulmonary volume was total lungs minus gross tumor volume.[ncbi.nlm.nih.gov] […] index (SI), pulmonary function, tumour location, serum Krebs von den Lungen-6 value (KL-6), dose-volume metrics (V5, V10, V20, V30, V40 and VS5), homogeneity index of the planning[ncbi.nlm.nih.gov] After wide excision of the right breast tumor and dissection of level I axillary lymph nodes, systemic therapy with oral 5-FU and tamoxifen was started.[ncbi.nlm.nih.gov]

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  • Kallmann Syndrome Type 3

    Thus, the treatment plan should be established according to the needs of the individual patient.[symptoma.com] Olfactory impairment may be partial or complete, and PROKR2 mutations have even been identified in apparently normosmic patients.[symptoma.com] Most KS3 patients respond well to hormonal therapy, develop normal sexual characteristics, and may even have children.[symptoma.com] The underlying gene defect should be identified to secure the diagnosis, to facilitate the identification of related carriers and possibly allow for prenatal diagnosis.[symptoma.com] Thus, the treatment plan should be established according to the needs of the individual patient.[symptoma.com] Orthopedic comorbidities and further birth defects require symptomatic treatment according to the respective guidelines; causal therapy is not available.[symptoma.com] In about 5% of cases, mutations in the PROKR2 gene can be identified. The respective patients are diagnosed with Kallmann syndrome type 3.[symptoma.com] ., he was able to maintain physiological levels of testosterone after the discontinuation of hormonal therapy.[symptoma.com] Distinct genotypes result in slight phenotypic differences, which may help to make a tentative diagnosis and to prioritize the sequencing of determined genes.[symptoma.com]

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  • Osteoporosis

    Reconsider treatment choice. Continue treatment.[patient.info] This large-scale meta-analysis provided replication evidence for several QTLs identified in previous studies and also identified a new QTL on chromosome 18p11-q12.3 [ 22 ][doi.org] Many national and international organizations now address screening and treatment for men in their osteoporosis clinical guidelines.[ncbi.nlm.nih.gov] […] the important role of autophagy in the pathogenesis of GIOP, here we review the potential mechanisms about the impacts of autophagy in GIOP and its association with GIOP therapy[ncbi.nlm.nih.gov] 2015 ICD-9-CM Diagnosis Code 733.0 Osteoporosis There are 5 ICD-9-CM codes below 733.0 that define this diagnosis in greater detail.[icd9data.com] Abstract This study was planned to evaluate the incidence and risk factors of osteoporosis and fracture after gastrectomy for stomach cancer using a nationwide claims database[ncbi.nlm.nih.gov] […] and intervention, screening for osteoporosis in patients with the NAFLD, especially those with lower income and co-morbid with diabetes mellitus and chronic obstructive pulmonary[ncbi.nlm.nih.gov] However, the combination therapy of anabolic agents and bisphosphonates reports no benefit and even reduced the anabolic effects of anabolic agents.[ncbi.nlm.nih.gov] Diagnosis and management of osteoporosis in patients with stages 1-3 CKD and patients without CKD are similar, but diagnosis and management decisions differ greatly once patients[ncbi.nlm.nih.gov]

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