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62 Possible Causes for E2F3

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  • Mesomelic Dysplasia, Savarirayan Type

    The deletions encompass four known genes: MBOAT1 , E2F3, CDKAL1 and SOX4. All patients showed mesomelia of the lower limbs with hypoplastic tibiae and fibulae.[jmg.bmj.com]

  • Persistent Hyperplastic Primary Vitreous

    […] partial trisomy 6p22 pter and persistent hyperplastic primary vitreous (PHPV) with retinal detachment: Forkhead box Q1 (FOXQ1), FOXF2, FOXC1, NRN1, EDN1, ATXN1, DEK oncogene, E2F3[ncbi.nlm.nih.gov]

  • Glioblastoma Multiforme

    Expression of a panel of seven microRNAs (hsa-miR-34a, hsa-miR-16, hsa-miR-17, hsa-miR-21, hsa-miR-221, hsa-miR-326, and hsa-miR-375) and seven target genes ( E2F3, PI3KCA[ncbi.nlm.nih.gov] Our data demonstrated a significant upregulation of five microRNAs (hsa-miR-16, hsa-miR-17, hsa-miR-21, hsa-miR-221, and hsa-miR-375), three genes ( E2F3, PI3KCA, and Wnt5a[ncbi.nlm.nih.gov]

  • Fibrolamellar Hepatocellular Carcinoma

    […] was increased expression of oncogenes associated with various cancers including pathways found in breast cancer: ErbB2 (EGF pathway) ( 32 ), Aurora Kinase A (AURKA) and E2F3[pnas.org] In the set of genes that are associated with pancreatic cancer, the FLHCC samples showed additional enrichment with the transcripts involved in the cell cycle (E2F1, E2F3,[pnas.org] , which is required for normal cell proliferation ( 85 ); and overexpression of E2F3, which has been associated with breast ( 86 ), prostate ( 87 ), and bladder cancer ( 88[pnas.org]

  • Malignant Melanoma

    E2F3 affects the melanoma cell glucose metabolism and growth.[ncbi.nlm.nih.gov] METHOD: QRT-PCR was used to detect the expression of lncRNA H19 and E2F3 was detected in melanoma tissues.[ncbi.nlm.nih.gov] Cell counting kit-8 (CCK8), representative metabolites analysis was used to explore the biological function of lncRNA H19, miR-106a-5p and E2F3 in melanoma cells.[ncbi.nlm.nih.gov]

  • Retinoblastoma

    […] phosphorylates LIN52, a component of p107- and p130-assembled transcriptionally repressive DREAM complexes that control transcription during the G0/G1 phases, and the Rb-associated E2F3[ncbi.nlm.nih.gov] Interacts with heterodimeric E2F/DP transcription factor complexes containing TFDP1 and either E2F1, E2F3, E2F4 or E2F5, or TFDP2 and E2F4.[uniprot.org] Recent studies identified gains and amplifications at 1q32 ( MDM4 and KIF14 genes) and 6p22 ( E2F3 and DEK genes) as M3 and M4 respectively.[atlasgeneticsoncology.org]

  • Amegakaryocytic Thrombocytopenia

    EXTL1, FEN1, FHIT, FER, FES, ETV3, ERG, ESRRA, FGF1, FGF7, EZH1, ETV7, ETS2, FBXO11, EREG, ESCO1, ESPL1, FBXO8, FGF6, ETV3L, FGR, FEV, FAT3, EPHA7, PHF1, ELF3, ELF2, DVL2, E2F3[mendelian.co]

  • Velocardiofacial Syndrome

    NFYB; ELK4; FOXQ1; IKZF3; MAFF; FOXD5 Function transcription factor activity, sequence-specific DNA binding Related Protein GLI2; ZNF334; MSC; FOXC1; TBX5; POU3F3B; GM239; E2F3[creativebiomart.net]

  • Vesicoureteral Reflux 8

    BANP; PCOLCE; TFAP2A; q7ard1_yerpe; purA; TFAP2C; E2F3 TNXB Related Articles Chen, XY; Li, R; et al.[creativebiomart.net]

  • Phakomatosis Pigmentokeratotica

    October 01, 2017 The role of miR-210, E2F3 and ephrin A3 in angiosarcoma cell proliferation.[medscape.com]

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