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2,088 Possible Causes for GABA, protein,, receptor associated, zebrafish

Did you mean: GABA, proteus, receptor associated, zebrafish

  • Hyperlipidemia

    […] domain containing adaptor protein)-MyD88-IRAK (interleukin-1 receptor-associated kinase)1/4-TRAF6 (TNF receptor-associated factor 6), leading to integrin activation via the[ncbi.nlm.nih.gov] KEYWORDS: Cadmium; Cholesteryl ester transfer protein; Embryo; Hyperlipidemia; Lipoprotein; Zebrafish[ncbi.nlm.nih.gov] ), dopamine (DA), 5-hydroxytryptamine (5-HT), N-methyl-D-aspartate (NMDA1R), GABA A , 5-HT 1 , D 1 , and apoptosis-related proteins Caspase3, bax, and bcl-2 were measured[ncbi.nlm.nih.gov] These factors were also associated with increased CVD risk.[ncbi.nlm.nih.gov]

  • Stress

    PA treatment was also associated with increased levels of angiotensinogen and angiotensin type 1 receptor (AT1R) mRNA expression.[ncbi.nlm.nih.gov] Abstract It is well established today that heterologous overexpression of proteins is connected with different stress reactions.[ncbi.nlm.nih.gov] In several regions of the central nervous system (CNS), SIS alters the level of neurotransmitter such as dopamine, serotonin, gamma aminobutyric acid (GABA), glutamate, nitrergic[ncbi.nlm.nih.gov] Using Light-sheet Fluorescence Microscopy, visualization of the developing zebrafish heart was possible.[ncbi.nlm.nih.gov]

  • Machado-Joseph Disease

    Because caffeine (a nonselective adenosine receptor antagonist) and selective adenosine A2A receptor (A2A R) blockade alleviate neurodegeneration in different brain diseases[ncbi.nlm.nih.gov] […] impairs misfolded protein clearance.[ncbi.nlm.nih.gov] […] a protein that accomplishes the proper positioning of GABA-A- and glycine receptors.[ncbi.nlm.nih.gov] This improves the movement of the MJD zebrafish.[ncbi.nlm.nih.gov]

  • Isoproterenol

    We questioned whether endogenous GABA(A) channels on airway smooth muscle could augment beta-agonist-mediated relaxation.[ncbi.nlm.nih.gov] […] determined that the adrenergic agonists phenylephrine (PE) and isoproterenol (ISO) can induce the production of β-hemoglobin embryonic 1 (hbbe1) mRNA and protein in adult zebrafish[ncbi.nlm.nih.gov] "Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists" .[en.wikipedia.org] Therefore, we investigated the protein expression profile and signaling transduction in HL-l cardiomyocyte cells treated with ET-1 and ISO.[ncbi.nlm.nih.gov]

  • Alexander Disease

    In the cerebellum, glutamine and GABA content and labeling from [1-(13)C]glucose were increased.[ncbi.nlm.nih.gov] To develop a vertebrate model to assess the aggregation tendency of GFAP, we expressed several previously reported mutant GFAPs and p.Asp128Asn GFAP in zebrafish embryos.[ncbi.nlm.nih.gov] Three of five proteins selected for follow-up were confirmed enriched in the RF fraction by immunobloting of both the AxD mouse models and human patients: receptor for activated[ncbi.nlm.nih.gov] The topological analysis of human protein interaction network strategy to identify highly interconnected sub-network modules from which six proteins are found i.e.[ncbi.nlm.nih.gov]

  • Lissencephaly

    The precursors of pyramidal neurons migrate radially, whereas most of the GABA-containing interneurons are generated in the ventral telencephalon and migrate tangentially[ncbi.nlm.nih.gov] We demonstrated that zebrafish consisted of two LIS1 genes, LIS1a and LIS1b.[ncbi.nlm.nih.gov] More recently, de novo missense mutations in the alpha-tubulin 1a gene (TUBA1A) located on chromosome 12q13.12, have also been associated with more or less severe defects[ncbi.nlm.nih.gov] It involves not only dynein and dynein-associated proteins such as LIS1 but also SUN proteins of the nuclear envelope.[ncbi.nlm.nih.gov]

  • Wolf Hirschhorn Syndrome

    […] are associated with the diverse pathological WHS phenotypes and their symptoms.[ncbi.nlm.nih.gov] Protein Name & Synonyms: Negative elongation factor A, NELF-A, Wolf-Hirschhorn syndrome candidate 2 protein, WHSC2, NELFA, FLJ10442, FLJ25112, P/OKcl.15.[raybiotech.com] Although fascinating, this theory is simplistic, since patients with Angelman syndrome without GABA deletion may present epilepsy and EEG abnormalities.[ncbi.nlm.nih.gov] […] genetics Zebrafish Proteins/genetics Zebrafish Proteins/metabolism Substances Adaptor Proteins, Signal Transducing CD2-associated protein Cytoskeletal Proteins Histones Intracellular[ncbi.nlm.nih.gov]

  • Motor Neuron Disease

    OBJECTIVE: To investigate the association between angiotensin converting enzyme inhibitors (ACEIs), angiotensin II receptors blockers (ARBs) and motor neuron disease (MND)[ncbi.nlm.nih.gov] Misfolded proteins accumulate and aggregate in neurodegenerative disease. The existence of these deposits reflects a derangement in the protein homeostasis machinery.[ncbi.nlm.nih.gov] Other GABA modulators have not been studied in randomized trials.[ncbi.nlm.nih.gov] A newly hatched zebrafish, riddled with the human gene that causes MND.[smh.com.au]

  • Dravet Syndrome

    CONCLUSIONS AND RELEVANCE: We conclude that the epilepsy phenotypic heterogeneity associated with GABRG2 mutations may be related to the extent of the reduction of GABAA receptor[ncbi.nlm.nih.gov] […] genetics Recombinant Proteins/metabolism Zinc/metabolism Substances GABRG2 protein, human Receptors, GABA-A Recombinant Proteins Zinc Grant support R01 NS033300/NS/NINDS[ncbi.nlm.nih.gov] To study the impact of depolarizing GABA onto distinct patterns of EEG activity, we extended a neural mass model as follows: one sub-population of pyramidal cells was added[ncbi.nlm.nih.gov] We also provide evidence that zebrafish larvae express the orthologues of all human 5-HT receptor subtypes.[ncbi.nlm.nih.gov]

  • Rubinstein-Taybi Syndrome

    Antibody-mediated encephalities, in which patients present with neurological syndromes associated with serum and/or CSF antibodies directed against ion channels, receptors[docksci.com] protein (EP300) (5%).[ncbi.nlm.nih.gov] We postulate other persons with RTS may respond to divalproex, and there may be some relationship between the chromosome 16p13.3 deletion and gamma-aminobutyric acid (GABA[ncbi.nlm.nih.gov] The zebrafish genome has two co-orthologs of lysine acetyltransferase EP300 (KAT3B) in zebrafish viz. ep300a and ep300b.[ncbi.nlm.nih.gov]