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412 Possible Causes for GDP, exchange, human, p21, protein,, smg, stimulatory

Did you mean: GDP, exchange, human, p21, proteus, smg, stimulatory

  • Carbachol

    The stimulatory effect of carbachol on PI turnover was completely abolished by the muscarinic receptor antagonist, atropine, but was unaltered by the nicotinic antagonist,[ncbi.nlm.nih.gov] In excised inside-out membrane patches from nonstimulated A9m3 cells GTP (10 microM) and GDP (10 microM) activated cation-selective channels with conductances of approximately[ncbi.nlm.nih.gov] Abstract The TAO (for thousand-and-one amino acids) protein kinases activate p38 mitogen-activated protein (MAP) kinase cascades in vitro and in cells by phosphorylating the[ncbi.nlm.nih.gov] SLC9A3 protein, human Slc9a3 protein, mouse Sodium-Hydrogen Exchanger 3 Sodium-Hydrogen Exchangers Cystic Fibrosis Transmembrane Conductance Regulator Carbachol Grant support[ncbi.nlm.nih.gov] The main outcome measures were the secretory flow rate and duct obstruction rate in the transplanted SMGs.[ncbi.nlm.nih.gov] Our data support an original transcriptional upregulation of human NPR-A in response to cAMP-induced agents, and in response to carbachol.[ncbi.nlm.nih.gov] The addition of 100 nm bovine insulin or 500 nm human insulin together with 3 mm glucose had no stimulatory effect on C-peptide secretion rates from perifused rat islets.[ncbi.nlm.nih.gov]

    Missing: p21
  • Lactobacillus Acidophilus

    Therefore albeit B. lactis still stimulates the effector Th cells but because of more stimulatory effect on Tregs, it could be a good potential therapeutic candidate for further[ncbi.nlm.nih.gov] The S-layer protein was extracted with 5M LiCl and the active fraction purified by gel filtration (G-75).[ncbi.nlm.nih.gov] […] effects on Cl /OH exchange activity.[ncbi.nlm.nih.gov] This study was carried out to investigate the characteristics of Lactobacillus acidophilus, a typical probiotic for humans, under simulated microgravity (SMG) conditions.[ncbi.nlm.nih.gov] IMPORTANCE Starch is one of the most abundant glycans in the human diet.[ncbi.nlm.nih.gov] When cells were treated with a combination of live LAB and 5-FU, a faster activation of caspase-3 protein was observed, and the p21 protein seems to be downregulated.[ncbi.nlm.nih.gov] The current studies were designed to elucidate the molecular mechanisms mediating the stimulatory effects of LA CS on Pgp promoter activity.[ncbi.nlm.nih.gov]

    Missing: GDP
  • Entamoeba Histolytica

    […] activation, α5β1 integrin induced ATP release into the extracellular space through opening of pannexin-1 channels that signalled through P2X7 receptors to deliver a critical co-stimulatory[ncbi.nlm.nih.gov] The crystal structure of ARF1 from E. histolytica has been determined bound to magnesium and GDP at 1.8 Å resolution.[ncbi.nlm.nih.gov] KEYWORDS: ALIX family proteins; EhADH; Entamoeba histolytica; cysteine proteases; molecular dynamics simulation; proteinprotein docking[ncbi.nlm.nih.gov] The discovery of amoebic trogocytosis in E. histolytica may also shed light on an evolutionarily conserved process for intercellular exchange.[ncbi.nlm.nih.gov] Distance to human settlements explained the variation in E. histolytica infection seen in lemurs.[ncbi.nlm.nih.gov] Abstract Rho family GTPases modulate actin cytoskeleton dynamics by signaling through multiple effectors, including the p21-activated kinases (PAKs).[ncbi.nlm.nih.gov] The spatiotemporal dynamics of vacuolar EhRab35 and its exchange with soluble cytosolic pool were monitored by fluorescence recovery after photobleaching experiments.[ncbi.nlm.nih.gov]

    Missing: smg
  • Malignant Mesothelioma

    Previous research at pre-clinical and clinical levels into targets including IL-2, IFN-γ and a number of co-stimulatory molecules have provided a promising impact upon immune[annalscts.com] protein processing in the endoplasmic reticulum.[ncbi.nlm.nih.gov] Abstract The Na /H exchanger is responsible for maintaining the acidic tumor microenvironment through its promotion of the reabsorption of extracellular Na and the extrusion[ncbi.nlm.nih.gov] KEGG, Biocarta, PID, and Reactome databases were used for further pathway enrichment analysis for the identified SMGs.[karger.com] The present study was performed to investigate mechanisms underlying the hypoxia-induced phenotypic changes using human malignant mesothelioma (HMM) cells.[ncbi.nlm.nih.gov] Gallic acid restrained the activation of EGFR, ERK1/2 and AKT proteins and down regulated expression of Cyclin D and Bcl-2 genes, but upregulated the expression of p21 gene[ncbi.nlm.nih.gov] In this study, quantitative proteomics was used to investigate MM-derived exosomes from distinct human models and identify select cargo protein networks associated with angiogenesis[ncbi.nlm.nih.gov]

    Missing: GDP
  • Euphorbia

    Henceforth, Immuno-stimulatory strategies targeting neutrophilic function are indeed powerful tools in combating obstinate infections.[ncbi.nlm.nih.gov] HYPOTHESIS: Among lectins are the ribosome-inactivating proteins (RIPs), which are potent inhibitors of protein synthesis in cells and in cell-free systems.[ncbi.nlm.nih.gov] Cytotoxicity of plant methanol and chloroform fractions was examined towards human acute myeloid leukemia (THP1) and human colon epithelial (Caco2) cancer cell lines, as well[ncbi.nlm.nih.gov] Cell cycle arrest was associated with down-regulation of cyclin B and Cdk-1 and subsequent up-regulation of p53 and p21.[ncbi.nlm.nih.gov] YZ is supported by the International Postdoctoral Exchange Fellowship Program 2015 awarded by the Office of China Postdoctoral Council.[frontiersin.org] However, despite showing the most potent human CYP3A4 promoter activity via a PXR-independent pathway, 2 did not affect CYP3A4 mRNA expression in human primary hepatocytes[ncbi.nlm.nih.gov] Although these classification systems are useful to guarantee consistency, data exchange and comparability among different studies 16 , 18 , they have two major drawbacks.[nature.com]

    Missing: smg
  • Ethanol

    The stimulatory effect of ethanol and acetone on human keratinocytes may be one of the reasons why psoriasis can be precipitated by alcohol misuse.[ncbi.nlm.nih.gov] The renewable fuels industry (including biodiesel) supports around 42,000 jobs in Iowa and accounts for 4.7 billion of Iowa’s GDP. Ethanol is good for Iowa all right.[iowacorn.org] Therefore, the present study was undertaken to evaluate the role of ABC transporters and heat shock proteins mediated response in human neural precursor cells (NPCs) and its[ncbi.nlm.nih.gov] BACKGROUND/AIMS: To functionally characterize intracellular pH (pHi) regulating mechanisms, such as Na -H exchanger (NHE) and Na -HCO3- co-transporter (NBC), and further examine[ncbi.nlm.nih.gov] AntagomiR-451 efficiently protected GES-1 cells and primary human GECs from ethanol-induced viability reduction and apoptosis.[ncbi.nlm.nih.gov] […] analysis demonstrated that BSGLEE induces apoptosis and cell cycle arrest at G0/G1 phase, which are associated with deregulation of the expression of key genes and proteins (p21[ncbi.nlm.nih.gov] […] has been invested in infrastructure and expanded production capacity, creating an industry that is responsible for nearly 400,000 jobs and contributes 44 billion to the GDP[motherboard.vice.com]

    Missing: smg
  • Arteriovenous Malformation

    Mutations were missense or small in-frame deletions that affect amino acid residues within or adjacent to the protein's negative regulatory domain.[ncbi.nlm.nih.gov] The venes dissipate the used blood after the oxygen exchange took place through small vasculature, the so-called capillary bed.[uniklinik-freiburg.de] SMG I and II), B (i.e. SMG III) or C (i.e. SMG IV and V). EVIDENCE SYNTHESIS: The primary search produced 116 papers.[ncbi.nlm.nih.gov] In this study, we described LncRNAs profiles in 4 pairs of human brain arteriovenous malformation(AVM) and the corresponding fragment of superior temporal arteries(STA) or[ncbi.nlm.nih.gov] Etiology The syndrome is caused by heterozygous mutations in the RASA1 gene (5q13.3), encoding RAS p21 protein activator 1.[orpha.net] The surgically removed oblate Onyx cast did not contain brain tissue or vessel wall, and immunohistochemical staining against glial fibrillary acidic protein (GFAP) showed[ncbi.nlm.nih.gov] An AVM disrupts the normal exchange of blood between arteries and veins.[stanfordhealthcare.org]

    Missing: stimulatory
  • Cervical Cancer

    T cells from being suppressed IL-2/IL-2R: activating this cytokine pathway can help promote the growth and expansion of cancer-fighting T cells OX40: activating this co-stimulatory[cancerresearch.org] TPD7 inhibited HeLa cell invasion by downregulating the expression of matrix metalloproteinase (MMP)-9 and CXCR4 proteins.[ncbi.nlm.nih.gov] Coordination of the dissemination and exchange of information.[canada.ca] SMGs are ordered by the overall mutation frequency and colour-coded by mutation type. Novel SMGs identified in squamous cell carcinomas are labelled in turquoise text.[nature.com] Malondialdehyde levels (8.02nmols/mL) were almost five times higher in human papillomavirus-positive compared to human papillomavirus-negative women (1.70nmols/mL) living[ncbi.nlm.nih.gov] Lupeol induced S-phase cell cycle arrest and also decreased the expression of S-phase Cyclins and CDKs and increased the expression of cyclin-dependent kinase inhibitors, p21[ncbi.nlm.nih.gov] CONCLUSIONS: Our results revealed that SNAP23 suppressed progression of CC and induced cell cycle G2/M arrest via upregulating p21 cip1 and downregulating CyclinB1.[ncbi.nlm.nih.gov]

    Missing: GDP
  • Adenosine

    Inhibition of the stimulatory effect of adenosine signalling on angiogenesis using specific pharmacological adenosine receptor agonist, and antagonist is a potentially novel[ncbi.nlm.nih.gov] Azathioprine Methotrexate Mycophenolic acid Pemetrexed Pralatrexate Many others Others Precursors: Adenine Adenosine AMP ADP ATP Cytosine Cytidine CMP CDP CTP Guanine Guanosine GMP GDP[en.wikipedia.org] […] and mineralization of osteoblasts via enhancing expression of bone morphogenetic protein (BMP)-2, which is a potent inducer of osteoblastogenesis.[ncbi.nlm.nih.gov] KEYWORDS: CdTe quantum dot; Ion-exchange reaction; Multiple cycle amplification; Silver nanoclusters[ncbi.nlm.nih.gov] Abstract The human O-acetyl-ADP-ribose deacetylase MDO1 is a mono-ADP-ribosylhydrolase involved in the reversal of post-translational modifications.[ncbi.nlm.nih.gov] The major causes of excessive DSBs in H1299 cells are as follows: First, defect of p53-p21 signal and phosphorylation of SMC1 increase S phase cells, where replication of[ncbi.nlm.nih.gov] Caffeine's stimulatory effects are primarily (although not entirely) credited to its inhibition of adenosine by binding to the same receptors.[psychology.wikia.com]

    Missing: smg
  • Momordica Charantia

    Due to their immune-stimulatory activities and their ability to increase T-helper 1 cell cytokines, total fruit and leafy stem juices may serve in the treatment of immunodeficiency[ncbi.nlm.nih.gov] Abstract This review describes the nature and applications of ribosome inactivating proteins (RIPs) from Momordica charantia (bitter melon).[ncbi.nlm.nih.gov] In order to obtain sufficient samples for researches, a strategy combining ion-exchange and gel filtration chromatography was developed and optimized in this study.[ncbi.nlm.nih.gov] […] gourd treatment in humans.[ncbi.nlm.nih.gov] […] addition, KuJ markedly decreased the levels of cyclins (D1 and E), cyclin-dependent kinases (Cdk2 and Cdk4) and proliferating cell nuclear antigen, and caused an increase in p21[ncbi.nlm.nih.gov] Further studies revealed that BME treatment enhanced p53, p21, and pChk1/2 and inhibited cyclin B1 and cyclin D1 expression, suggesting an additional mechanism involving cell[ncbi.nlm.nih.gov] -4 is due to reduced expression of Bcl-2 and increased expression of Bax leading to increased expression of caspase-3 and affecting the expression of cell cycle proteins p21[ncbi.nlm.nih.gov]

    Missing: GDP smg