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376 Possible Causes for ICR

  • Meningitis

    Combined treatment with interleukin-12 and mebendazole lessens the severity of experimental eosinophilic meningitis caused by Angiostrongylus cantonensis in ICR mice.[doi.org]

  • Corneal Ectasia

    Numerous questions concerning ICRS remain, including the duration of the effects of ICRS and the changes that ICRS induce on a biomechanical level.[ncbi.nlm.nih.gov] CONCLUSIONS: ICRS-CXL and ICRS alone were both safe and effective in treating corneal ectasia.[ncbi.nlm.nih.gov] ICRS do not consistently decrease corneal aberrations.[ncbi.nlm.nih.gov]

  • Keratoconus

    PURPOSE: To evaluate a four-stage combined treatment for keratoconus including intrastromal corneal ring segment (ICRS) implantation followed by corneal cross-linking (CXL[ncbi.nlm.nih.gov] The ICRS implantation is done with CXL to stop the progression of the disease.[ncbi.nlm.nih.gov] METHODS: Medical records of 23 eyes of 23 patients undergoing combined tPRK and CXL after ICRS implantation were retrospectively analyzed.[ncbi.nlm.nih.gov]

  • Pellucid Marginal Degeneration

    ICRS implantation can delay penetrating keratoplasty and improve contact lens tolerance, but does not treat the underlying process.[ncbi.nlm.nih.gov] PURPOSE: To evaluate refractive, visual, and aberrometric changes in corneas with pellucid marginal degeneration (PMD) implanted with intracorneal ring segments (ICRS) during[ncbi.nlm.nih.gov] OBJECTIVE: To evaluate the use of the intracorneal ring (ICR; Intacs, Addition Technology, Inc., Fremont, CA) for the treatment of pellucid marginal degeneration (PMD).[ncbi.nlm.nih.gov]

  • Osteochondritis Dissecans

    The OCD criteria of the ICRS were applied to arthroscopy and imaging interpretations.[ncbi.nlm.nih.gov] ICRS OCD I lesions (n 6) showed no intralesional separation.[ncbi.nlm.nih.gov] An ICRS OCD I or II lesion with central positioning and/or occupying 2016 The Author(s).[ncbi.nlm.nih.gov]

  • Beckwith-Wiedemann Syndrome

    We analyzed these regions in 19 healthy pregnancies and highlighted stable methylation levels between CVF and CVC at ICR1, ICR2, GNASXL, PWS/AS-ICR, and MEST.[ncbi.nlm.nih.gov] […] epigenetic changes that disrupt the parent-of-origin specific expression of these genes. [2, 3] Most commonly, BWS is caused by epigenetic modifications to methylation at ICRs[emedicine.com] In addition, PWS/AS-ICR, GNASXL, and MEST, but not GNAS1A and ZAC/PLAGL1, are steadily hemimethylated in CV from healthy pregnancies, independently from culture.[ncbi.nlm.nih.gov]

  • High Fat Diet

    ICR mice were fed the AIN-76 diet, or high-fat diet (HFD), or the RCD- or SRCD-supplemented HFD (10%, w/w) for 9 weeks (n   7 per group).[ncbi.nlm.nih.gov] Furthermore, we found that mice treated with ICRE have improved cold tolerance during acute cold challenge.[ncbi.nlm.nih.gov] The ICR mice received high-fat diet (HFD) continuously for 12 weeks after two weeks of acclimatization with a standard chow diet, and the mice fed with a standard chow diet[ncbi.nlm.nih.gov]

  • Calcific Tendinitis of the Shoulder

    The remaining 107 shoulders had incomplete resorption (ICR) (ICR group). Gartner type I calcification was most common (64.5%) in the ICR group.[ncbi.nlm.nih.gov] Most frequently, glenohumeral articular cartilage was either entirely intact (ICRS grade 0 (humeral head/glenoid): 46%/48%) or showed very mild degenerative changes (ICRS[ncbi.nlm.nih.gov] The mean duration of symptoms before ESWT was significantly longer in the ICR group. Overall, 81% of the CR group and 23.4% of the ICR group were symptom free.[ncbi.nlm.nih.gov]

  • Poliovirus

    ICR-PVRTg1 and ICR-PVRTg5 showed the highest and the lowest sensitivity to poliovirus, respectively, whereas ICR-PVRTg21 was in-between.[doi.org] Recombinant viruses between the virulent Mahoney and attenuated Sabin 1 strains of poliovirus type 1 were subjected to neurovirulence tests using a transgenic (Tg) mouse line, ICR-PVRTg1[jvi.asm.org] Those in ICR-PVRTg21 and ICR-PVRTg5 were at intermediate and lowest levels, respectively.[doi.org]

  • Russell-Silver Syndrome

    To further characterize the role of epimutations in RSS we evaluated the methylation status at both 11p15.5 imprinting control regions (ICRs): ICR1 associated with H19/IGF2[ncbi.nlm.nih.gov] […] that epimutations on chromosome 11p15 can be most efficiently detected in RSS patients by screening for DNA methylation defects at the H19 promoter or the distal region of ICR[ncbi.nlm.nih.gov] Alterations in the methylation of certain cluster of genes result in differentially methylated regions (DMR′s) or imprinting control regions (ICR′s).[symptoma.com]

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