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387 Possible Causes for IMP, synthase

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  • Enterococcus Faecalis

    We selected Thymidylate synthase (TS) from this organism as a potential specific target for antibacterial therapy.[] Elektronen-Synchrotron (DESY), Hamburg, Germany. 6 Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences, Vienna, Austria. 7 Research Institute of Molecular Pathology (IMP[] […] that infecting unencapsulated E. faecalis cps2 is a stronger stimulator for toll like receptor 2 (TLR2) and interleukin-1β (IL-1β) mRNAs, but not for inducible nitric oxide synthase[]

  • Zellweger Syndrome

    Three peroxisomal integral membrane proteins (IMPs) (69, 53 and 22 kDa) were present in normal amounts in all the Zellweger and adrenoleukodystrophy samples and they sedimented[] Indeed, cells defective in dihydroxyacetone phosphate acyltransferase (DHAP-AT) or alkyl-DHAP synthase express only the diacyl form of GPI-anchored proteins.[] […] in the peroxisomal biogenesis factors PEX5, PEX16, and PEX19 and in cells from patients with RCDP types 1, 2, and 3 caused by mutations in PEX7, DHAP-AT, and alkyl-DHAP synthase[]

  • Middle Cerebral Artery Occlusion

    RESULTS AND DISCUSSION: Distribution of delta waves was observed pre-operatively corresponding to areas of cerebral hypo-perfusion as confirmed by IMP-SPECT but disappeared[] Ozagrel, a thromboxane A(2) synthase inhibitor, inhibits platelet aggregation and causes vasodilatation, thereby increasing CBF in cerebral thrombosis.[] […] Abstract PATIENT AND METHODS: Cerebral blood flow and neuromagnetic activity were measured using (123)I-iodoamphetamine-single photon emission computed tomography (IMP-SPECT[]

  • Clofibrate

    We further show that 1.4 mM clofibric acid suppressed umami enhancement from GMP, but not from IMP.[] Surprisingly, the expression of lipogenic pathway genes including SREBP-1c (sterol regulatory element-binding protein-1c), HMG-CoA synthase, SPTLC1 (serine palmitoyltransferase[] Abstract In humans, umami taste can increase the palatability of foods rich in the amino acids glutamate and aspartate and the 5'-ribonucleotides IMP and GMP.[]

  • Polymyalgia Rheumatica

    Linear regression between PMR-AS and clin-PMR-AS [CRP-imp PMR-AS 1.12(clin-PMR-AS) 0.26] allowed us to build the CRP-imp PMR-AS.[] OBJECTIVES: We investigated the association of the T-786C single nucleotide polymorphism (SNP) of the endothelial nitric oxide synthase gene (NOS3), which is characterised[] CRP-imp PMR-AS agreed more closely with PMR-AS than did clin-PMR-AS. The results in the TENOR cohort confirmed that CRP-imp PMR-AS or ESR-PMR-AS could be used.[]

  • Placental Insufficiency

    In Groups 1 and 2, IRT% and IMP were increased (P 0.001) compared with the control group.[] Activity of NO synthase and the concentration of nitrites in the placenta in women with placental insufficiency and spontaneous abortions were below the normal.[] The proportion of left ventricular isovolumetric relaxation time (IRT%) of the cardiac cycle, and index of myocardial performance (IMP) were calculated.[]

  • Ischemic Cardiomyopathy

    This study investigates in situ cardiac regeneration utilizing precision delivery of a novel mesenchymal precursor cell type (iMP) during coronary artery bypass surgery (CABG[] Abstract The role of nitric oxide synthase 1 (NOS1) as a major modulator of cardiac function has been extensively studied in experimental models; however, its role in human[]

  • Grifola Frondosa

    Kinase 3/antagonists & inhibitors Glycogen Synthase Kinase 3/metabolism Grifola/chemistry* Grifola/metabolism Hep G2 Cells Hepatocytes/cytology Hepatocytes/drug effects*[] Alice Chen Commissioned to be written by UNICORN Imp. Mfg. Corp for reference by clients of Unicorn Imp. & Mfg. Corp.[] The expression of acetyl-CoA carboxylase, fatty acid synthase, and sterol regulatory element-binding protein 1c was decreased.[]

  • Francisella Tularensis

    KEYWORDS: Francisella tularensis; IMP dehydrogenase; complex I[] […] demonstrated that PGE(2) synthesis by F. tularensis-infected macrophages requires cytosolic phospholipase A2 (cPLA(2)), cyclooxygenase 2 (COX-2), and microsomal prostaglandin E synthase[] The virulence of F. tularensis is decreased by deletion of guaB , the gene encoding IMP dehydrogenase (IMPDH), suggesting that this enzyme is a target for antibacterial design[]

  • Nitrofurantoin

    Carbapenem-resistant Enterobacteriaceae present an increasing and diverse problem, including strains of multiple species with metallo-β-lactamases (IMP, NDM or VIM) and non-metallo[] Complementing ST2747-an with a functional wild-type lumazine synthase restored nitrofurantoin susceptibility.[] We identified a 12-nucleotide deletion in ribE, encoding lumazine synthase, an essential enzyme involved in the biosynthesis of flavin mononucleotide (FMN), which is an important[]

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