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110 Possible Causes for Immunotoxin, LMB 9

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  • Trichosanthes Kirilowii

    Purification, partial characterization and use for preparation of immunotoxins . Eur J Biochem. 176 , 581–588 (1988). 4. Lee-Huang, S. et al.[nature.com]

    Missing: LMB 9
  • Promyelocytic Leukemia

    Immunotoxins, such as gemtuzumab ozogamicin, may find certain cancer cells and kill them without harming normal cells.[clinicaltrials.gov]

    Missing: LMB 9
  • Diphtheria Toxoid

    Ex-vivo treatment of donor bone marrow with anti-T-cell immunotoxins for prevention of graft-versus-host disease.[nature.com] Resimmune is an immunotoxin that is in clinical trials in Cutaneous T cell lymphoma patients.[en.wikipedia.org] Immunotoxins: a new approach to cancer therapy. Science 219 : 644–650. 15 Cawley, D.B., Herschman, H.R., Gilliland, D.G. and Collier. R.J. 1980.[nature.com]

    Missing: LMB 9
  • Toxic Effect

    Abstract Immunotoxins are chimeric proteins consisting of a toxin coupled to an antibody.[ncbi.nlm.nih.gov] The percentage of AnnexinV cells was over 95% in both cell lines treated with 10 nM immunotoxin.[ncbi.nlm.nih.gov] A complete elimination of Raji clones was reached with the 10 nM immunotoxin, whereas a mixture of free RIP and mAb gave about 90% of clonogenic growth.[ncbi.nlm.nih.gov]

    Missing: LMB 9
  • T-cell Acute Lymphoblastic Leukemia

    These recombinant immunotoxins were expressed in Escherichia coli and showed that nanobody immunotoxins have the benefits of easy soluble expression in a prokaryotic expression[ncbi.nlm.nih.gov] METHODS AND RESULTS: Three new types of immunotoxins, dhuVHH6-PE38, dVHH6-PE-LR, and dhuVHH6-PE-LR, were successfully constructed.[ncbi.nlm.nih.gov] In our previous efforts, we have successfully generated the monovalent and bivalent CD7 nanobody-based immunotoxins, which can effectively trigger the apoptosis of CD7-positive[ncbi.nlm.nih.gov]

    Missing: LMB 9
  • Sambucus

    KEYWORDS: ribosome-inactivating proteins; Sambucus; endoglin (CD105); immunotoxin; transferrin[ncbi.nlm.nih.gov] The lack of toxicity of type 2 RIPs from Sambucus make them good candidates as toxic moieties in the construction of immunotoxins and conjugates directed against specific[ncbi.nlm.nih.gov]

    Missing: LMB 9
  • Shigella Dysenteriae

    […] efficient immunotoxins.[cordis.europa.eu] Toxins of this group are extensively used to form immunotoxins for targeted cytotoxic therapy, and knowledge of the translocation mechanism is essential for development of[cordis.europa.eu]

    Missing: LMB 9
  • Methotrexate

    Eur J Med Chem. 2018 Oct 5;158:502-516. doi: 10.1016/j.ejmech.2018.09.027. Epub 2018 Sep 13. Author information 1 State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wailong, Taipa, Macau, China. 2 State Key Laboratory of Quality Research in Chinese Medicine,[…][ncbi.nlm.nih.gov]

    Missing: LMB 9
  • Thiotepa

    Bju International 94(3): 317-321, 2004 Prevention of postoperative recurrence of human bladder carcinoma by intravesical instillation of immunotoxin, a clinical study .[eurekamag.com]

    Missing: LMB 9
  • Corynebacterium Diphtheriae

    Página 33 - Phase I trial of recombinant immunotoxin Anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies. ‎[books.google.es]

    Missing: LMB 9

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