Show results in: Español
A Microbial Biorealm page on the genus Human JC Polyomavirus Classification Higher order taxa Viruses; dsDNA viruses, no RNA stage; Polyomaviridae; Polyomavirus Species JC[microbewiki.kenyon.edu] Most humans encounter BK and JC virus during childhood, causing mild illness.[ncbi.nlm.nih.gov] Abstract Agnoprotein is an important regulatory protein of the human polyoma JC virus (JCV) and plays critical roles during the viral replication cycle.[ncbi.nlm.nih.gov]
It is caused by the replication of polyomavirus JC (JCV) in the oligodendrocytes and astrocytes leading to their cytolytic death and loss of myelin from the subcortical white[ncbi.nlm.nih.gov] The JC virus is a common infection completely unrelated to MS. Between 40-90% of the general population have been exposed to JC virus.[mstrust.org.uk] Sequence analysis of lesional brain tissue identified PML-associated viral mutations in regulatory (non-coding control region) DNA, capsid protein VP1, and the regulatory agnoprotein[ncbi.nlm.nih.gov]
We present two cases of BK polyomavirus-associated nephropathy who were submitted to contrasting strategies of clinical follow-up to BK polyomavirus reactivation, but progressed[ncbi.nlm.nih.gov] JC Virus (BK/JC) PCR Kit BKJC/ISEX/050 real-time PCR 50 reactions GeneProof BK/JC Virus (BK/JC) PCR Kit BKJC/ISEX/100 real-time PCR 100 reactions[geneproof.com] Human polyomavirus JC small regulatory agnoprotein forms highly stable dimers and oligomers: implications for their roles in agnoprotein function.[antimicrobe.org]
BK and JC are both members of the polyomavirus family.[ncbi.nlm.nih.gov] Epub 2012 Jan 25. de Jong MM, Nolte IM, te Meerman GJ, van der Graaf WT, Oosterwijk JC, Kleibeuker JH, Schaapveld M, de Vries EG.[ghr.nlm.nih.gov] Can J Neurol Sci. 2009; 36 :462–7. [ PubMed : 19650357 ] Zhang Q, Davis JC, Lamborn IT, Freeman AF, Jing H, Favreau AJ, Matthews HF, Davis J, Turner ML, Uzel G, Holland SM[ncbi.nlm.nih.gov]
Abstract The human polyomavirus JC virus (JCV) is the agent of progressive multifocal leukoencephalopathy (PML).[ncbi.nlm.nih.gov] (E) Coimmunostaining of polyomavirus and neurofilaments. Magnification, 400. Polyomavirus-infected cells are stained in red (*) and neurofilaments in brown (arrowheads).[jcm.asm.org] In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology in Clinical Practice . 7th ed. Philadelphia, PA: Elsevier; 2016:chap 96. Ma MJ.[medlineplus.gov]
The clinical picture, MRI imaging, and positive JC virus PCR in CSF strongly suggest ruxolitinib-related JC virus meningitis.[ncbi.nlm.nih.gov] Moris G, Garcia-Monco JC (June 1999). "The challenge of drug-induced aseptic meningitis" (PDF) .[en.wikipedia.org] KEYWORDS: JC virus meningitis; Myelofibrosis; Ruxolitinib[ncbi.nlm.nih.gov]
OBJECTIVE: To review the literature regarding the use of intravesicular cidofovir in the treatment of polyomavirus-associated hemorrhagic cystitis.[ncbi.nlm.nih.gov] Prognostic value of JC virus load in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy. J Infect Dis 178 : 1816–1820.[link.springer.com] Another patient had milder symptoms of cystitis and intermittent polyomavirus shedding.[ncbi.nlm.nih.gov]
Polyomavirus BK (BKPyV) and JC (JCPyV) infect asymptomatically around 80% of general population worldwide remaining latent in the body.[ncbi.nlm.nih.gov] Bethesda (MD): National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2009. 3 Peralta CA, Kurella M, Lo JC, et al.[healthypeople.gov] Tong A, Chapman JR, Wong G, de Bruijn J, Craig JC. Screening and follow-up of living kidney donors: a systematic review of clinical practice guidelines.[nejm.org]
Progressive multifocal leukoencephalopathy (PML) is a destructive and often fatal infection of oligodendrocytes caused by the human polyomavirus JC virus (JCV). 1 Risk factors[cp.neurology.org] Progressive multifocal leukoencephalopathy (PML) is a destructive and often fatal infection of oligodendrocytes caused by the human polyomavirus JC virus (JCV). 1 Risk factors[cp.neurology.org]
Experimental Design: Serum samples from patients with MCC were analyzed for the presence and titer of antibodies against antigens of the oncogenic Merkel cell polyomavirus[ncbi.nlm.nih.gov] Kumar V, Abbas AK, Aster JC. Diseases of the immune system. In: Kumar V, Abbas AK, Aster JC, eds. Robbins and Cotran Pathologic Basis of Disease . 9th ed.[nlm.nih.gov] Hachulla E 1 , Le Masson G 2 , Solé G 2 , Hamidou M 3 , Desnuelle C 4 , Azulay JP 5 , Besson G 6 , Swiader L 7 , Abad S 8 , Antoine JC 9 , Bouhour F 10 , Créange A 11 , Grenouillet[ncbi.nlm.nih.gov]