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9 Possible Causes for LANP

  • Morphea

    Integrated switch on the lanp head Eye friendly optic with reduced reflection for reading.[amazon.com]

  • Spinocerebellar Ataxia Type 1

    In addition, we find that depleting the Leucine-rich Acidic Nuclear Protein (LANP)-an ATXN1 binding inhibitor of histone acetylation-reverses aspects of SCA1 neuritic pathology[ncbi.nlm.nih.gov] As LANP interacts with ataxin 1--a protein mutated in the neurodegenerative disease spinocerebellar ataxia type 1 (SCA1)--we tested whether ataxin 1 can alter the E4F -LANP[wikigenes.org] Neurol. (2001) [ Pubmed ] The role of LANP and ataxin 1 in E4F-mediated transcriptional repression.[wikigenes.org]

  • Spinocerebellar Ataxia Type 5

    As LANP interacts with ataxin 1--a protein mutated in the neurodegenerative disease spinocerebellar ataxia type 1 (SCA1)--we tested whether ataxin 1 can alter the E4F -LANP[wikigenes.org] Neurol. (2001) [ Pubmed ] The role of LANP and ataxin 1 in E4F-mediated transcriptional repression.[wikigenes.org] Anatomical context of ATXN1 LANP is expressed predominantly in Purkinje cells , the primary site of pathology in SCA1 [1] .[wikigenes.org]

  • Autosomal Dominant Mental Retardation 21

    Classification of the Spinocerebellar Ataxias (SCA) Name Locus Phenotype SCA1 (autosomal dominant type 1) 6p22-p23 with CAG repeats (exonic); leucine-rich acidic nuclear protein (LANP[accesspharmacy.mhmedical.com]

  • Atrophies Muscular Spinobulbar

    When the ataxin-1 is altered , its interaction with LANP is also altered . The ataxin-1 is said to “sequester” the LANP and thus interfere with its normal activity.[web.stanford.edu] After a time, the sequestering of LANP appears to cause degeneration of the nerve cell .[web.stanford.edu] Scientists believe that LANP has a major effect on cell communication, which is needed for the survival of a nerve cell .[web.stanford.edu]

  • Familial Congenital Mirror Movements 2

    Lung Cancer - Ovarian Cancer - Pancreatic Cancer - Uterine Sarcoma SMAD3 15q22.33 LDS3, LDS1C, MADH3, JV15-2, HSPC193, HsT17436 - Breast Cancer - Liver Cancer ANP32A 15q23 LANP[cancerindex.org]

  • Pancreatic Carcinoma

    Pancreatic Cancer 2 CDCP1 3p21.31 CD318, TRASK, SIMA135 - CDCP1 and Pancreatic Cancer 2 HLA-C 6p21.3 HLC-C, D6S204, PSORS1, HLA-JY3 - HLA-C and Pancreatic Cancer 1 ANP32A 15q23 LANP[cancerindex.org]

  • Homozygous 11p15-p14 Deletion Syndrome

    15q21.1 D-PCa-2, C15orf21 - HMGN2P46 and Prostate Cancer 1 CDR2 16p12.3 Yo, CDR62 - CDR2 and Prostate Cancer 1 PDE11A 2q31.2 PPNAD2 - PDE11A and Prostate Cancer 1 ANP32A 15q23 LANP[cancer-genetics.org]

  • Ring Chromosome 15

    ) (Mapmodulin) (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Putative HLA-DR-associated protein I) (PHAPI) [C15orf1] [LANP] [MAPM] [PHAP1] ANPEP 15q25-q26[uniprot.org] P39687 AN32A_HUMAN 600832 Acidic leucine-rich nuclear phosphoprotein 32 family member A (Acidic nuclear phosphoprotein pp32) (pp32) (Leucine-rich acidic nuclear protein) (LANP[uniprot.org]

Further symptoms