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34 Possible Causes for MAPKK, activation, activity, of

Did you mean: MAPKK, amotivation, activity, of

  • Enoxacin

    It has a broad spectrum of in vitro antibacterial activity, and is particularly potent against Gram-negative organisms and staphylococci.[ncbi.nlm.nih.gov] […] quinoxalin-2-yl)-2-thiophenecarboxamide Purity: 98% (HPLC) Biological Activity T-LAK-cell-originated protein kinase (TOPK) inhibitor; exhibits selectivity for TOPK over other MAPKK[tocris.com] Against many of the common Enterobacteriaceae enoxacin displayed a similar degree of activity as gentamicin.[ncbi.nlm.nih.gov] Abstract The in vitro activities of enoxacin, lomefloxacin, norfloxacin, ofloxacin, and pefloxacin against 274 strains of Salmonella typhi isolated from suspected typhoid[ncbi.nlm.nih.gov]

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  • Chronic Fatigue Syndrome

    The 26-session graded activity intervention involved gradual increases in physical activity.[ncbi.nlm.nih.gov] Sequential phosphorylation of MAPK kinase kinase (MAPKKK) and MAPK kinase (MAPKK/MEK1/2) activates ERK1/2 through dual phosphorylation of threonine and tyrosine residues [[dx.doi.org] Such approaches do not provide information on either the severity of symptoms or on fluctuations in symptom severity and activity level that occur over time.[ncbi.nlm.nih.gov] The trial's poor results on objective measures of fitness suggest a lack of adherence to the activity component of these therapies.[ncbi.nlm.nih.gov]

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  • Candida Albicans

    In this study, we examined their antifungal activity against C. albicans in vitro.[ncbi.nlm.nih.gov] Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK . Science 276 , 1702–1705 (1997). 119. Smith, D.[doi.org] Herein, we report a structure-activity relationship study on this peptide with the aim of designing a more potent peptide for further development.[ncbi.nlm.nih.gov] KEYWORDS: 1,3-Dimethylxanthines; Antibiofilm activity; Anticancer activity; Fungicidal activity; Proxyphylline analogues; Selective toxicity[ncbi.nlm.nih.gov]

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  • Lymphangioleiomyomatosis

    Cathepsin K gene expression and protein and protease activity were detected in LAM-associated fibroblasts but not the LAM cell line 621-101.[ncbi.nlm.nih.gov] Further phosphorylation events occur downstream via mitogen activated protein kinase kinase (MAPKK) and mitogen activated protein kinase (MAPK) resulting in the upregulation[thorax.bmj.com] Given the role of NK cells in immune surveillance, we postulated that NK cell activating receptors and their cognate ligands are involved in LAM pathogenesis.[ncbi.nlm.nih.gov] METHOD: We measured physical activity (steps per day, SPD; physical activity level, PAL; minutes of moderate activity, MMA) in 34 women with LAM, 32 FEV1-matched female patients[ncbi.nlm.nih.gov]

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  • Bacillus Anthracis

    A UV-based enzymatic activity assay was then used to select inhibitory compounds.[ncbi.nlm.nih.gov] Highly specific protease component that cleaves members of the mitogen-activated protein kinase kinase (MAPKK) family.[sigmaaldrich.com] Passive transfusion of mice with pulsed BMDC, concurrently with active immunisation with rPA in alum, significantly enhanced (p[ncbi.nlm.nih.gov] We discovered that while B. anthracis 34F2 Sterne endospores germinate poorly within non-activated human PMNs, these phagocytes exhibit rapid microbicidal activity toward[ncbi.nlm.nih.gov]

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  • Pseudomonas Aeruginosa

    Abstract Ceftolozane/tazobactam is a novel antimicrobial agent with activity against Pseudomonas aeruginosa and other common Gram-negative pathogens.[ncbi.nlm.nih.gov] Interestingly, compromising the p38 MAPK cascade, including by mutations in tir-1 /SARM, nsy-1 /MAP3K, sek-1 /MAPKK, and pmk-1 /p38 or by RNAi-mediated knockdown of PMK-1[doi.org] No β-lactam-avibactam combination was active against Achromobacter xylosoxidans.[ncbi.nlm.nih.gov] Herein, different essential oils extracted from Mediterranean plants were analyzed for their activity against P. aeruginosa .[ncbi.nlm.nih.gov]

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  • Yersinia Pestis

    Pla favors fibrinolysis by direct activation of plasminogen, inactivation of the serpins plasminogen activator inhibitor-1 and α2-antiplasmin, inactivation of the thrombin-activable[ncbi.nlm.nih.gov] […] mitogen-activated protein kinase (MAPK) and the nuclear factor κB (NFκB) signaling pathways used in innate immune response by preventing activation of the family of MAPK kinases (MAPKK[doi.org] Furthermore, a direct interaction of MAPKKs and IKKβ with YopJ has been reported ( 9 ). Fig. 3.[doi.org] Click to hear Dr Bock discuss pathogen activators of plasminogen.[ncbi.nlm.nih.gov]

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  • Carotenoid

    PCC 7120 were purified, and their cleavage activities were investigated.[dx.doi.org] Several MAPKs and MAPKKs have been shown to be regulated by ABA by both increased expression and activation (reviewed in Liu, 2012 ).[doi.org] The extent of antineoplastic effects, however, did not seem to correlate with the carotenoid content and antioxidant activity of the two tomato varieties.[ncbi.nlm.nih.gov] Retinol Activity Equivalent: 10737mcg Beef, variety meats and by-products, liver, cooked, braised Retinol Activity Equivalent: 9442mcg Goose, liver, raw Retinol Activity[nutritiondata.self.com]

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  • Oncogenic Osteomalacia

    It is unlikely, therefore, that the HEM-1 product is the active factor responsible for oncogenic osteomalacia.[ncbi.nlm.nih.gov] Raf-Kinase-Signalwegs mittels Verabreichung von deaktivierenden Antikörpern gegen Raf-Kinase oder mittels Koexpression dominanter negativer Raf-Kinase oder dominanter negativer MEK (MAPKK[encrypted.google.com] We then compared RNA from tumor-derived cultures expressing inhibitory activity with RNA from tumor-derived cultures in which inhibitory activity was not evident and identified[ncbi.nlm.nih.gov] Support for the diagnosis was obtained by detection of phosphate uptake inhibitory activity in a blinded sample of the patient's serum using a renal cell bioassay.[ncbi.nlm.nih.gov]

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  • Isotretinoin

    […] responsiveness to T cell mitogens, suggesting that the drug activity included suppression of an effector T cell response.[jci.org] Cytochrome P450, family 24, subfamily A, polypeptide 1 70,126.96 0.0010 Steroid metabolic process NM_002506 Nerve growth factor (β polypeptide) 66,907.97 0.0023 Activation of MAPKK[iovs.arvojournals.org] Retinoids Induce the Activity of the D2R Promoter in Transfected Cells.[doi.org] The immunosuppressive activity of 13-cRA included suppression of interleukin 2, whose production was inhibited in splenocytes.[jci.org]

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