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232 Possible Causes for MRD

  • Urinary Tract Infection

    In contrast, all isolates resistant to augmentin and nitrofurantoin were MRD, while 72.7 and 82.4% of isolates resistant to ciprofloxacin and cefazolin were MDR.[ncbi.nlm.nih.gov]

  • B-Precursor Acute Lymphoblastic Leukemia

    RESULTS: MRD results were concordant in 91 of the 108 paired samples (84.2%; K 0.690); 49 samples were MRD-negative while 42 were MRD-positive by both methods, with 1 log[ncbi.nlm.nih.gov] We classified patients as "best risk" if they had cleared MRD by day 8 of therapy and as "worst risk" if they had MRD remaining in bone marrow at day 28, and tested whether[ncbi.nlm.nih.gov] Given the strong association of MRD and outcome in non-Down syndrome (non-DS) BP-ALL, it is likely that MRD levels are also of prognostic significance in DS BP-ALL.[ncbi.nlm.nih.gov]

  • Childhood Acute Lymphoblastic Leukemia

    […] in a misleading assessment of the true level of marrow MRD.[ncbi.nlm.nih.gov] […] risk) levels of MRD.[ncbi.nlm.nih.gov] […] possible implications for MRD detection.[ncbi.nlm.nih.gov]

  • Congenital Ptosis

    Excellent lid height was assessed as a marginal reflex distance (MRD) greater than 3 mm.[ncbi.nlm.nih.gov] RESULTS: At postoperative day seven and 30, MRD of both the groups were good but on three months follow-up MRD of silicon rod group dropped, however it was not statistically[ncbi.nlm.nih.gov] Eyelid parameters including LMF, lid fissure height (LFH) and margin reflex distance (MRD) were measured in both eyes and analyzed.[ncbi.nlm.nih.gov]

  • Blepharoptosis

    Success was defined as a MRD at the last postoperative visit of 3 mm.[ncbi.nlm.nih.gov] Postoperative MRD-1 and change in MRD-1 were not correlated to ΔR.[ncbi.nlm.nih.gov] The difference in the surgical methods and MRD 3, 6 and 12 months after operation did not reach statistical significance.[ncbi.nlm.nih.gov]

  • Acute Lymphoblastic Leukemia

    MRD was successfully quantified in patients with 1-month interval time.[ncbi.nlm.nih.gov] […] on day 19 or 0.01% MRD on day 46.[doi.org] 10–4) MRD patients presented a pattern of OS, LFS, RI and NRM that was not significantly different from that observed in “low risk” (MRD 10–4) MRD patients.[haematologica.org]

  • T-cell Acute Lymphoblastic Leukemia

    Collectively, TFDP3 confers chemoresistance in MRD within childhood T-ALL, indicating that TFDP3 is a potential gene therapy target for residual cancer.[ncbi.nlm.nih.gov] Patients with MRD positivity at the time of transplant had significantly higher rates of progression compared with those with MRD negativity (76 vs 34%, hazards ratio 2.8,[ncbi.nlm.nih.gov] Their MRD were evaluated by SIL-TAL1, Wilms' tumor 1 (WT1) expression, and the leukemia-associated immunophenotype (LAIP) .[ncbi.nlm.nih.gov]

  • Hairy Cell Leukemia

    To determine, using MRD and tumor marker data, when BMBx can be avoided. To compare response and MRD after the 1st and 2nd courses of cladribine.[clinicaltrials.gov] Of the 9 CRs, 8 remain free of MRD at 12 to 48 (median 27) months of follow-up.[ncbi.nlm.nih.gov] Complete remission to single-agent purine analog is often accompanied by minimal residual disease (MRD), residual HCL cells detectable by immunologic methods, considered a[ncbi.nlm.nih.gov]

  • B-Cell Chronic Lymphocytic Leukemia

    Patients will continue IBR VEN for the same duration of time as it took them to achieve MRD negativity (i.e. patients who are MRD negative after 6 months IBR VEN will stop[bloodjournal.org] CONCLUSION: The 8-color CLL-MRD assay provides a more informative approach than its predecessors for the assessment of MRD in B-CLL by functioning as an important disease[ncbi.nlm.nih.gov] RESULTS: The overall response, minimal residual disease (MRD) -negative complete response (CR), MRD-positive CR, and partial response rates were 93%, 46%, 36%, and 11%, respectively[ncbi.nlm.nih.gov]

  • Chronic Lymphocytic Leukemia

    Patients will continue IBR VEN for the same duration of time as it took them to achieve MRD negativity (i.e. patients who are MRD negative after 6 months IBR VEN will stop[bloodjournal.org] RESULTS: The overall response, minimal residual disease (MRD) -negative complete response (CR), MRD-positive CR, and partial response rates were 93%, 46%, 36%, and 11%, respectively[ncbi.nlm.nih.gov] Current goals of CLL therapies are to produce deep and durable, especially minimal residual disease (MRD)-negative, remissions so as to allow patients to ultimately discontinue[ncbi.nlm.nih.gov]

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