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582 Possible Causes for Metalloproteases

  • Amebic Liver Abscess

    Am J Trop Med Hyg. 2017 Oct;97(4):1214-1217. doi: 10.4269/ajtmh.17-0258. Epub 2017 Jul 19. Author information 1 Department of Medicine, McMaster University, Hamilton, Ontario, Canada. 2 Department of Radiology, McMaster University, Hamilton, Ontario, Canada. 3 Department of Clinical Epidemiology and Biostatistics, McMaster[…][]

  • Cyanotic Congenital Heart Disease

    Abstract Changes in plasma von Willebrand factor concentration (VWF:Ag) and ADAMTS-13 activity (the metalloprotease that cleaves VWF physiologically) have been reported in[]

  • Fibrinolysis

    In accordance with these findings, inhibition of TAFIa increased secretion of matrix metalloprotease proenzymes by endothelial and breast cancer cells.[]

  • Immune Thrombocytopenic Purpura

    The deficiency in ADAMTS13 metalloprotease, which cleaves the von Willebrand factor, may be congenital or acquired.[]

  • Prion Disease

    PrP(C) is shed at the plasma membrane by the metalloprotease ADAM10, yet the impact of this on prion disease remains enigmatic.[] In contrast to α- and β-cleavage where there is an ongoing controversy on the identity of relevant proteases, the metalloprotease ADAM10 represents the only relevant PrP sheddase[]

  • Vibrio Parahaemolyticus

    V. parahaemolyticus expresses the metalloproteases; PrtV, VppC, VPM and the serine proteases; VPP1/Protease A, VpSP37, PrtA.[] This review summarizes findings on the metalloproteases and serine proteases produced by V. parahaemolyticus and their roles in infections.[] The pathogenicity of V. parahaemolyticus has been linked to the expression of different kinds of virulence factors including extracellular proteases, such as metalloproteases[]

  • Myopathy

    Abstract The "A disintegrin and metalloprotease" (ADAM) family is thought to play an important role in tissue destruction and inflammatory reactions.[]

  • Didanosine

    The role of exposure to antiretrovirals (ARV) and serum matrix metalloproteases (MMPs) on liver fibrosis (LF) progression in human immunodeficiency virus (HIV) mono or HIV[]

  • Chronic Bronchitis

    Abstract We investigated the association of matrix metalloproteinases, the disintegrin and metalloprotease 33 and the tissue and serum inhibitors of proteinase gene polymorphisms[]

  • Arterial Thrombosis

    ADAMTS13 metalloprotease cleaves von Willebrand factor (VWF), thereby inhibiting platelet aggregation and arterial thrombosis.[]

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