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2,813 Possible Causes for Muscle, spindle

  • Myopericytoma

    Microscopically, it was composed of densely packed spindle cells organized as whorls and short interlacing fascicles with a concentric perivascular distribution.[ncbi.nlm.nih.gov] Imaging suggested that a mass had originated in the middle scalene muscle.[ncbi.nlm.nih.gov] In some areas, fascicles of spindle cells, embedded in a myxoid stroma, bulged into the lumina of lesional vessels, reminiscent of myofibroma/myofibromatosis.[ncbi.nlm.nih.gov]

  • Leiomyosarcoma

    On histopathological analysis, all the classic features were noted and diagnosis of a spindle cell neoplasm was made without any obscurity.[ncbi.nlm.nih.gov] […] of Muscle Clinical Examination of Leiomyosarcoma of Muscle How is Leiomyosarcoma of Muscle Diagnosed?[myvmc.com] Histopathological examination showed spindle cells with nuclear mitoses.[ncbi.nlm.nih.gov]

  • Pleomorphic Rhabdomyosarcoma

    All tumors had large, often multinucleated, polygonal, spindled or strap-like rhabdomyoblasts with abundant eosinophilic cytoplasm.[ncbi.nlm.nih.gov] […] showing smooth-muscle and fibrohistiocytic differentiation.[ncbi.nlm.nih.gov] On the other hand, only two types of tumor cells (spindle-shaped and spiderweb cells) were scattered or present in clusters in the LBC specimens.[ncbi.nlm.nih.gov]

  • Sunburn

    A novel mutation in the XPA gene associated with unusually mild clinical features in a patient who developed a spindle cell melanoma.[ncbi.nlm.nih.gov] A disabling myalgia in the thigh at the DPT site in one child may also have been the result of localization of the varicella virus in the muscle during the inapparent viremic[ncbi.nlm.nih.gov] […] call NHS 111 if: your skin is blistered or swollen your temperature is very high, or you feel hot and shivery you feel very tired, dizzy and sick you have a headache and muscle[nhs.uk]

  • Inflammatory Myofibroblastic Tumor

    The tumor has spindle cell proliferation with a prominent inflammatory infiltrate and myxoid degeneration favoring other designations such as inflammatory pseudotumor and[ncbi.nlm.nih.gov] We resected the tumor to the depth of the muscle layer, but normal muscle tissue was not seen. We consequently diagnosed this tumor as a muscle-invasive bladder tumor.[karger.com] Abstract Inflammatory myofibroblastic tumor (IMT) is an uncommon tumor characterized by inflammatory cell infiltration and differentiated myofibroblastic spindle cells.[ncbi.nlm.nih.gov]

  • Malignant Neoplasm

    The tumor cells ranged from round to polygonal with abundant cytoplasm to elongated spindle cells with scant cytoplasm.[ncbi.nlm.nih.gov] […] drastically reduces the incidence of "undifferentiated" diagnoses and will optimize patient management, as illustrated by two cases of large-cell lymphoma arising in skeletal muscle[ncbi.nlm.nih.gov] The majority of SMN are osteosarcomas, spindle cell and pleomorphic sarcomas of soft tissues, and hematolymphoid malignancies.[ncbi.nlm.nih.gov]

  • Dementia

    Changes in sleep architecture that have been documented in AD include a reduction in stage N3 (slow wave) sleep, reduced fast spindle activity (a component of stage N2), and[doi.org] Your loved one might have: Memory and concentration problems Poor judgment Confusion Mood swings Depression Sleep problems Twitching or jerky muscles Trouble walking Normal[webmd.com] And as with brain cells, muscle cells are high energy users.[scientificamerican.com]

  • Rhabdomyosarcoma

    Spindle-cell RMS, a favorable prognostic variant of embryonal RMS, should be considered in the cytologic diagnosis of soft-tissue tumors with round cell and spindle cell morphology[ncbi.nlm.nih.gov] Presence of laminin alpha5 chain and lack laminin alpha1 chain during human muscle development and in muscular dystrophies. J. Biol. Chem. 272: 28590-28595, 1997.[atcc.org] Non-neoplastic skeletal muscle fiber nuclei stained positively for myogenin in both tumor-associated samples (25 of 40) and benign skeletal muscle samples (5 of 11).[ncbi.nlm.nih.gov]

  • Dermatofibrosarcoma Protuberans

    Histologic evaluation of the specimen showed a spindle cell lesion consisting of fibroblast-like cells arranged in a storiform pattern.[ncbi.nlm.nih.gov] BACKGROUND: Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing cutaneous tumor that can invade the subcutaneous tissue, muscle tissue, and even bone.[ncbi.nlm.nih.gov] Histologically, the primary and recurrent tumors comprised a high-grade spindle cell sarcoma, with a small component of storiform, low-grade, CD34-positive spindle cells,[ncbi.nlm.nih.gov]

  • Embryonal Rhabdomyosarcoma

    Microscopically, the TUR specimen almost comprised a fascicular proliferation of spindle-shaped tumor cells, leading to the diagnosis of spindle cell sarcoma.[ncbi.nlm.nih.gov] Neoplasms/diagnosis Muscle Neoplasms/etiology* Muscle Neoplasms/surgery Neoplasms, Post-Traumatic/diagnosis Neoplasms, Post-Traumatic/etiology* Neoplasms, Post-Traumatic[ncbi.nlm.nih.gov] Despite the expression of early muscle specific genes, RMS cells fail to complete myogenesis even in differentiation conditions.[ncbi.nlm.nih.gov]

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