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67 Possible Causes for N Methyltransferase, Phosphatidylethanolamine

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  • Ezetimibe

    Mice lacking phosphatidylethanolamine N -methyltransferase (PEMT) are protected from high-fat diet (HFD)-induced obesity and insulin resistance.[ncbi.nlm.nih.gov] Mice lacking phosphatidylethanolamine N -methyltransferase (PEMT) are protected from high-fat diet (HFD)-induced obesity and insulin resistance.[ncbi.nlm.nih.gov]

  • Bacillus Subtilis

    […] subtilis DSM 3257, membranes of the I'1a strain were characterized by an increased amount of anteiso fatty acids and a ten-fold higher ratio of phosphatidylglycerol (PG)-to-phosphatidylethanolamine[ncbi.nlm.nih.gov] The key enzyme for plant Cho synthesis is phosphoethanolamine N-methyltransferase (PEAMT), which catalyzes all three methylation steps, including the rate-limiting N-methylation[ncbi.nlm.nih.gov]

  • Cold Exposure

    KEYWORDS: adipose tissue; hypertension; obesity; phosphatidylcholine; phosphatidylethanolamine; phosphatidylethanolamine N-methyltransferase[ncbi.nlm.nih.gov] Abstract Mice that lack phosphatidylethanolamine N-methyltransferase (Pemt(-/-) mice) are protected from high-fat (HF) diet-induced obesity.[ncbi.nlm.nih.gov] Abstract Mice that lack phosphatidylethanolamine N-methyltransferase (Pemt(-/-) mice) are protected from high-fat (HF) diet-induced obesity.[ncbi.nlm.nih.gov]

  • Spinal and Bulbar Muscular Atrophy

    Mass spectrometry analysis revealed an increase of phosphatidylethanolamines and phosphatidylserines in mitochondria isolated from SBMA muscles, as well as a 50% depletion[ncbi.nlm.nih.gov] Muscular Disorders, Atrophic/genetics Muscular Disorders, Atrophic/metabolism Nuclear Proteins/metabolism PC12 Cells Peptides/genetics* Phosphorylation Protein-Arginine N-Methyltransferases[ncbi.nlm.nih.gov] […] metabolism* Substances Drosophila Proteins Nuclear Proteins Peptides RNA, Messenger Receptors, Androgen polyglutamine PRMT6 protein, human PRMT6 protein, mouse Protein-Arginine N-Methyltransferases[ncbi.nlm.nih.gov]

  • Vinblastine

    We showed that cobalamin-induced increase in cell phosphatidylcholine production was phosphatidylethanolamine-methyltransferase-dependent.[ncbi.nlm.nih.gov] "Partial purification of an N-methyltransferase involved in vindoline biosynthesis in Catharanthus roseus." Phytochemistry, 32(3):673-678.[metacyc.org] […] antagonists & inhibitors Phosphatidylethanolamine N-Methyltransferase/metabolism Phospholipase D/antagonists & inhibitors Phospholipase D/metabolism* S-Adenosylmethionine[ncbi.nlm.nih.gov]

  • Infantile Refsum Disease

    […] examples of peroxisomal disorders neonatal adrenoleukodystrophy (NALD) bile acid synthesis derived from cholesterol phospholipid modification alter phosphatidylserine and phosphatidylethanolamine[medbullets.com] PubMed Google Scholar Kerr SJ, Heady JE (1973) Purification and characterization of glycine N-methyltransferase. J Biol Chem 248: 69–72.[link.springer.com] PubMed CrossRef Google Scholar Yeo E-J, Wagner C (1994) Tissue distribution of glycine N-methyltransferase, a major folate-binding protein of liver.[link.springer.com]

  • Phenylketonuria

    […] patients with phenylketonuria and 18 age-matched healthy control subjects LCPUFA-levels in plasma phospholipids and cholesteryl esters, erythrocyte phosphatidylcholine and phosphatidylethanolamine[ncbi.nlm.nih.gov] Epinephrine then is synthesized from norepinephrine via methylation of the primary distal amine of norepinephrine by phenylethanolamine N-methyltransferase (PNMT).[newworldencyclopedia.org] […] scores of DHA-levels in erythrocyte parameters from the respective age-matched control group and patients' concurrent and long-term phenylalanine levels for erythrocyte phosphatidylethanolamine[ncbi.nlm.nih.gov]

  • Fish-Eye Disease

    Analysis of his EM lipids revealed normal cholesterol and phospholipid content but a marked increase in phosphatidylcholine with concomitant decreases in phosphatidylethanolamine[ncbi.nlm.nih.gov] Guanidinoacetat-N-Methyltransferase GAMT 19p13.3 Snyder-Robinson-S. Spermin-Synthase SMS Xp22.1 PHGDH-Def.[de.wikibooks.org] Glycin-N-Methyltransferase GNMT 6p12 Hereditäre sensorische Neuropathie I Serin-C-Palmitoyltransferase SPTLC1 9q22.1-q22.3 Farber Lipogranulomatose Ceramidase ASAH1 8p22-p21.3[de.wikibooks.org]

  • Nortriptyline

    […] prodrugs ) Acetyl-coA Adafenoxate Choline ( lecithin ) Citicoline Cyprodenate Dimethylethanolamine Glycerophosphocholine Meclofenoxate (centrophenoxine) Phosphatidylcholine Phosphatidylethanolamine[en.wikipedia.org] Possible explanations for methylation include genetic polymorphisms in cytochrome P450 metabolizing enzymes, polymorphism of amine N-methyltransferase enzyme, drug-drug interactions[ncbi.nlm.nih.gov]

  • Hypoalphalipoproteinemia

    Analysis of his EM lipids revealed normal cholesterol and phospholipid content but a marked increase in phosphatidylcholine with concomitant decreases in phosphatidylethanolamine[ncbi.nlm.nih.gov] Hyperlipidämie, kombinierte Hyperlipidämie, seltene Hyperlipoproteinämie Typ 1 Hyperlipoproteinämie Typ 3 Hyperlipoproteinämie Typ 5 Hyperlysinämie Hypermethioninämie durch Glycin N-Methyltransferase-Mangel[se-atlas.de]

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