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2,726 Possible Causes for NO mediated, signal, transduction

  • Influenza

    […] could lead to a new class of drugs targeting the essential polymerase function of “cap-snatching.” 5 Other promising antiviral avenues under investigation include signal transduction[doi.org] Abstract Immune-mediated necrotizing myopathy is a very rare inflammatory disease affecting skeletal muscles.[ncbi.nlm.nih.gov] To insure efficient transport across the nuclear membrane, these viruses use nuclear import and export signals exposed on the vRNPs.[ncbi.nlm.nih.gov]

  • Glucocorticoid

    Cidlowski at the Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, 111 T.W.[doi.org] The GR can also mediate rapid nongenomic signaling events initiated in the cytoplasm.[ncbi.nlm.nih.gov] Possible mediators of glucocorticoid effects on the brain and behavior, as well as possible "pro-aging" effects of glucocorticoids in certain cells of the body, will be reviewed[ncbi.nlm.nih.gov]

  • Urinary Tract Infection

    Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F (1992) Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction.[dx.doi.org] Thus, these glycoside antagonists of FmlH represent a rational antivirulence strategy for UPEC-mediated UTI treatment. Copyright 2018 the Author(s). Published by PNAS.[ncbi.nlm.nih.gov] TLR4-mediated expulsion of bacteria from infected bladder epithelial cells . Proc. Natl Acad. Sci. USA 106 , 14966–14971 (2009). 29.[doi.org]

  • Viral Lower Respiratory Infection

    Our transfection and transduction analyses show that this process is disrupted in the presence of any of the IFIH1 rare variants found in our study population.[pnas.org] […] transport, which removes water from the alveolar space by osmosis: Viral hemagglutinin binds to receptors on respiratory epithelial cells, inhibiting epithelial sodium-channel–mediated[nejm.org] The flow signal from the pneumotachograph was integrated to give volume (Validyne CD280: Validyne Engineering).[thorax.bmj.com]

  • Sunburn

    Once the signal of excessive radiation exposure is initiated, it generally takes four to six hours for these proteins to generate.[scientificamerican.com] Separation of oxidant-initiated and redox regulated steps in the NF-kappa B signal transduction pathway . Proc Natl Acad Sci USA 1994 ; 91 : 11527 – 11531 . 9 .[doi.org] […] membrane phospholipids releases polyunsaturated fatty acids, and their subsequent metabolism by cyclooxygenases (COXs) and lipoxygenases (LOXs) may produce potent eicosanoid mediators[ncbi.nlm.nih.gov]

  • T-cell Acute Lymphoblastic Leukemia

    In addition to their pathophysiological relevance, receptors and kinases involved in signal transduction are often attractive candidates for targeted drug development.[ncbi.nlm.nih.gov] Interleukin-7 and interleukin-7 receptor are essential for normal T-cell development and homeostasis, whereas excessive interleukin-7/interleukin-7 receptor-mediated signaling[ncbi.nlm.nih.gov] The identification of specific genomic alterations has contributed to identify strong oncogenic drivers and signaling pathways regulating leukemia growth.[ncbi.nlm.nih.gov]

  • Inflammation

    KEYWORDS: Akt phosphorylation; Inflammation; Macrophage foam cell; TLR4 signaling; mTORC2[ncbi.nlm.nih.gov] Mammalian signal transduction; regulation of translational initiation; cell cycle regulation; biochemistry and signaling pathway of mTOR/FRAP. October 2001. .[web.archive.org] Serhan Annual Review of Immunology The Role of Cell-Mediated Immune Responses in Resistance to Malaria, with Special Reference to Oxidant Stress Anthony C.[doi.org]

  • Osteoporosis

    The findings of the present study revealed that anti‑microRNA‑148a protected cells against ovariectomy‑induced osteoporosis through ERα by PI3K/AKT signaling.[ncbi.nlm.nih.gov] The heterogeneity of osteoporosis may be due not only to differences in the production of systemic and local regulators, but also to changes in receptors, signal transduction[web.archive.org] As this homeodomain-disrupting and predicted truncating mutation resides within the final exon of SATB2, escape from nonsense-mediated decay is likely.[ncbi.nlm.nih.gov]

  • X-Linked Severe Combined Immunodeficiency

    These results clearly indicated that gamma c is essential for activation of Jak3 and STAT6 in the signal transduction pathway of IL-4 in human B cells and that IL-13 does[ncbi.nlm.nih.gov] Moreover, the reconstituted gamma-c restored function to the IL-2 and IL-4 receptors as shown by signal transduction mediated by phosphorylation of the JAK1 and JAK3 members[ncbi.nlm.nih.gov] These results suggest that two distinct IL-4 signaling pathways exist.[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    The main risks to the athlete are spontaneous splenic rupture (seen in 0.1%-0.5% of patients and signaled by acute abdominal pain) and progression to chronic fatigue, best[ncbi.nlm.nih.gov] A recurrent lesson of the book is that the virus parasitizes every cell system: signal transduction, cell-cycle control, regulation of gene expression, posttranscriptional[doi.org] CASE CHARACTERISTICS: A 17-year-old boy with Epstein-Barr virus related infectious mononucleosis and cold antibody-mediated autoimmune hemolytic anemia with incidentally noted[ncbi.nlm.nih.gov]