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636 Possible Causes for P ATP, compound

  • Viral Lower Respiratory Infection

    In a true negative, the internal control will amplify, whereas if the internal control fails to amplify, this would indicate inhibitory compounds in the sample which were[] Expression levels of the IFIH1 isoforms are shown under the plot in the Western blot gel. * P 0.05, ** P 0.01, *** P 0.001. ( B ) RNA-induced ATPase activity of purified IFIH1[] IFIH1-wt was able to hydrolyze ATP and showed a typical dsRNA-dependent increase in enzymatic activity, whereas the mutant isoforms had no detectable ATPase activity, even[]

  • Tuberculosis

    TBA-7371 is an antimicrobial compound that belongs to a novel class of drugs known as DprE1 inhibitors, of which there are two other compounds in early development.[] Lu P, et al. 2011. Pyrazinoic acid decreases the proton motive force, respiratory ATP synthesis activity, and cellular ATP levels . Antimicrob.[] A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis .[]

  • Phenothiazine

    These compounds did not show any apparent mutagenic activity, but rather be antimutagenic.[] Phenothiazine maleates-induced stimulation of ATP-dependent uptake of 2',7'-bis-(3-carboxyethyl)-5-(and-6)-carboxyfluorescein (BCECF) into inside-out membrane vesicles prepared[] On the other hand, a high dose of compound 6 caused cell death in both types of culture cells.[]

  • Curcumin

    Sign up for email alerts on Compounding August 4, 2017 Summary Two patients administered infusions of curcumin (a component of the spice turmeric) compounded with polyethylene[] Curcuminoids may interfere with the activity of efflux drug transporters of the ATP -binding cassette (ABC) family, including P-glycoprotein, multidrug resistance protein[] Also, compounds 5, 6 and 7 exhibited significant inhibitory activity against histamine.[]

  • Cantharidin

    Compounds 11 and 12 had anticancer potential similar to that of compound 10.[] CEM/ADR5000 and CEMJ/VLB100 are characterized by over-expression of the MDR-mediating ATP-binding cassette (ABC) transporter P-glycoprotein ( MDR1, ABCB1 ), while CEM/E1000[] In vitro the compound did not exhibit a therapeutic window, being equally toxic to normal HSCs and LSCs. In vivo cantharidin did not produce myelosuppression.[]

  • Digitoxin

    Attractively, among these compounds there are 24 compounds CC50 of which was less than 2.5 μM were identified.[] Abstract Digoxin is a drug with a narrow therapeutic index, which is substrate of the ATP-dependent efflux pump P-glycoprotein.[] Forms of Compound in ChEMBL Compound Bioactivity Summary Compound Assay Summary Compound Target Summary Calculated Compound Parent Properties Structural Alerts There are[]

  • Toxic Effect of Antimony

    […] and its compounds 985.3 Toxic effect of beryllium and its compounds 985.5 Toxic effect of cadmium and its compounds 985.6 Toxic effect of chromium 985.8 Toxic effect of other[] DNA Repair (Amst) 6: 923-935. [19] Baumann, P., Benson, F. E. and West, S. C. (1996).[] 985.1 - Toxic effect of arsenic and its compounds 985.2 - Toxic effect of manganese and its compounds 985.3 - Toxic effect of beryllium and its compounds 985.5 - Toxic effect[]

  • Capsaicin

    It is an organic nitrogen compound belonging to the lipid group, but it is often erroneously classed among the alkaloids, a family of nitrogenous compounds with marked physiological[] However, due to intergroup variability, these effects of ATP and AMP were not statistically significant (0.125 p 0.998).[] Thus, the combination of both bioactives reduces the effectiveness of each compound to decrease the adipocyte size and induce WAT browning.[]

  • Carotenoid

    This study investigated whether the natural carotenoid crocetin and the synthetic compound AS101 protect the ovary against CPM by modulating SIRT1 and mitochondrial markers[] […] to NAD(P)H)] followed by a subsequent mitochondrial ATP synthesis.[] The accumulation patterns for PVA and tocochromanol compounds in developing grain of 23 PVA hybrids was studied, and nutritionally meaningful amounts of those compounds were[]

  • Novobiocin

    […] in ChEMBL Molecule Features Withdrawal Information Mechanism of Action Clinical Data Compound Bioactivity Summary Compound Assay Summary Compound Target Summary Calculated[] Autophosphorylation of Hsp90 was analysed by incubation with gamma(32)P-ATP.[] P. Tingey and A. Maxwell , Probing the Role of the ATP-Operated Clamp in the Strand-Passage Reaction of DNA Gyrase , Nucleic Acids Research , 24 , 24 , (4868) , (1996) .[]

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