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498 Possible Causes for PGE2

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  • Osteoporosis

    Dietary (n–3) and (n–6) polyunsaturates and acetylsalicylic acid alter ex vivo PGE2 biosynthesis, tissue IGF-I levels, and bone morphometry in chicks .[ajcn.org]

  • Tuberculosis

    NGAL, HNP1–3, and MMP-9 formed another cluster, which was linked to LL-37 and PGE2.[ncbi.nlm.nih.gov] Serum PGE2 concentration was analyzed by high-sensitivity competitive enzyme immunoassay (Assay Designs).[ncbi.nlm.nih.gov] […] neutrophil gelatinase-associated lipocalin (NGAL), and cathelicidin (LL-37)]; this cluster was close to neutrophils, CXC chemokine ligand 8 (CXCL8), and prostaglandin E2 (PGE2[ncbi.nlm.nih.gov]

  • Primary Hypertrophic Osteoarthropathy

    The levels of PGE2 in urine were much higher than normal in all patients, along with lower PGE-M levels.[ncbi.nlm.nih.gov] Genetic studies have identified the impaired PGE2 metabolism as a culprit for hypertrophic osteoarthropathy in PHO cases.[ncbi.nlm.nih.gov] Change history 26 June 2008 In the version of this article initially published, Figure 3a—d and Supplementary Figure 2a—c show 16-OH PGE2, not 15-OH PGE2.[doi.org]

  • Acute Inflammation

    […] vascular permeability and edema formation via EP3 receptor on mast cells, and PGE2 increases blood flow by eliciting vasodilatation via EP2/EP4 receptors on smooth muscle[ncbi.nlm.nih.gov] This review is aimed at describing the functions of Prx1 and Prx6 in the regulation of PGD2 and PGE2 production in acute inflammation in macrophages and the importance of[ncbi.nlm.nih.gov] Inhibiting post-resolution prostanoids using naproxen showed that numbers of tissue memory CD4 cells were under the endogenous control of PGE2, which exerts its suppressive[ncbi.nlm.nih.gov]

  • Antenatal Bartter Syndrome

    CONCLUSION: In patients with HPS/aBS, excessive PGE2 synthesis and hyperreninemia is dependent on COX-2 activity.[ncbi.nlm.nih.gov] Additionally urine levels of prostaglandines PGE2 und PGF2alpha are helpful.[moldiag.com] Inhibition of stimulated prostaglandin E2 (PGE2) formation with indomethacin results in a significant improvement of clinical symptoms and is therefore standard therapy.[ncbi.nlm.nih.gov]

  • Aspirin-induced Asthma

    PGE2 attenuated the bronchoconstrictive reactions in 10 patients, salbutamol in eight, and misoprostol in seven.[ncbi.nlm.nih.gov] In addition, PGE2 may be involved in regulation of CD11b expression on eosinophils by aspirin administration.[ncbi.nlm.nih.gov] Low levels of PGE2 are found in patients of AERD, which is a respiratory protective prostaglandin.[healthunits.com]

  • Vaginal Pessary

    OBJECTIVE: The purpose of this study was to evaluate the effects of exogenous administration of PGE2 upon the components of the biophysical profile.[ncbi.nlm.nih.gov] PGE2 (dinoprostone 10 mg) by intravaginal pessary (n 49).[ncbi.nlm.nih.gov] 50% in the Atad and PGE2 gel groups.[ncbi.nlm.nih.gov]

  • Upper Airway Cough Syndrome

    After induced sputum cytology, the concentrations of histamine, prostaglandin E2 (PGE2), and calcitonin-gene-related peptide (CGPR) in the induced sputum were measured by[ncbi.nlm.nih.gov] Within the vagus nerve various mechanisms of hypersensitivity have been established, including that induced by prostaglandins, particular PGE2 [ 22 ].[coughjournal.biomedcentral.com] […] the levels of CGRP and histamine in the induced sputum decreased significantly in 15 patients with UACS, with no obvious change in cell differential or concentration of PGE2[ncbi.nlm.nih.gov]

  • Hyporeninemic Hypoaldosteronism

    Urinary prostaglandin E2 (PGE2) was suppressed (70 ng/24 h).[ncbi.nlm.nih.gov] Urinary PGE2 was decreased in 4 patients but was in the normal range in 5 other patients with HH.[ncbi.nlm.nih.gov] ., cirrhosis, CHF) PGI2 and PGE2 preferentially dilate the afferent arteriole thereby augmenting GFR.[renalfellow.blogspot.com]

  • Congenital Clubbing of the Fingers

    In congenital heart disease, blood bypasses the lungs, where PGE2 is normally broken down by 15-HPGD.[sciencedaily.com] […] hypertrophic osteoarthropathy lead topulmonary hypertrophic osteoarthropathy lead to decreased clearance and degradation of PGE2.decreased clearance and degradation of PGE2[slideshare.net] […] of megakaryocytes into systemic circulation or excessive PGE2 or VEGF production by tumors.[epomedicine.com]

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