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23 Possible Causes for PGRMC1, mouse, protein

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  • Endometriosis

    The mouse model recapitulated the human findings.[ncbi.nlm.nih.gov] […] validation results for 5 circRNAs ( circ_0004712, circ_0002198, circ_0003570, circ_0008951, and circ_0017248) and 8 mRNAs ( SCN3B, ENTPD1, IL16, BACH2, C3, CKS2, G0S2, and PGRMC1[ncbi.nlm.nih.gov] The degree of fibrosis in mouse endometriotic lesions was detected by Masson trichrome and Sirius red staining.[ncbi.nlm.nih.gov]

  • Uterine Sarcoma

    Taken together, our results show that PGRMC1 contributed to chemoresistance through cell proliferation, anti-apoptosis, and EMT induction, leading to the suggestion that PGRMC1[ncbi.nlm.nih.gov] 5/7), dishevelled protein (DVL), BAX, survivin and phosphorylated mitogen-activated protein kinase kinase (phospho-MEK) in all three lines; suppression of p27 and β-catenin[ncbi.nlm.nih.gov] MDR is also associated with the multidrug resistance-associated protein 1 (ABCC1) and the lung resistance-related protein (LRP), a human major vault protein.[ncbi.nlm.nih.gov]

  • Renal Cell Carcinoma

    The anti‑tumor activities of alisertib, an AURKA‑specific chemical inhibitor, were detected by Cell Counting Kit‑8 assay in vitro and mouse xenograft model in vivo.[ncbi.nlm.nih.gov] The present study suggests that the combined expression levels of PGRMC1 and ATP1A1 (PGRMC1/ATP1A1) are associated with the clinical prognosis of RCC patients.[ncbi.nlm.nih.gov] Objective: The aim of the study was to evaluate the expression of speckle-type POZ protein (SPOP) as a biomarker in patients with RCC.[ncbi.nlm.nih.gov]

  • Premature Ovarian Failure

    mouse model of POF.[ncbi.nlm.nih.gov] Abstract The gene PGRMC1 is highly expressed in the granulose and luteal cells of rodent and primate ovaries.[ncbi.nlm.nih.gov] Abstract Protein-losing enteropathy (PLE) and autoimmune oophoritis are unusual manifestations of systemic lupus erythematosus (SLE).[ncbi.nlm.nih.gov]

  • Immunosuppressive Drug

    Abstract We investigated the increased risk of Clostridium difficile infection (CDI) caused by the combined use of antibiotics and an immunosuppressive drug in a mouse model[ncbi.nlm.nih.gov] Furthermore, we investigated the mechanisms of HA prevention effects on POI, which was associated with promotion of GC proliferation and PGRMC1 expression.[ncbi.nlm.nih.gov] We identified several proteins and pathways as being involved in the mechanism of action of FTY720.[ncbi.nlm.nih.gov]

  • Progestin

    Electrophysiological studies showed that 3α, 5α-THNES exhibited only limited activity to enhance GABAAR-evoked responses with WSS-1 cells and did not modulate synaptic GABAARs of mouse[ncbi.nlm.nih.gov] These studies revealed that PGRMC1, PGRMC2, PAQR7, and PGR were expressed by granulosa/luteal cells from all patients, with PGRMC1 mRNA being most abundant, followed by PAQR7[ncbi.nlm.nih.gov] INTRODUCTION: Use of combined oral contraceptives (COCs) results in acquired protein S (PS) deficiency, a well-established risk factor for venous thromboembolism (VTE).[ncbi.nlm.nih.gov]

  • Anthracycline

    Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells . Mol. Cell.[nature.com] Interestingly, patients with high PGRMC1 tumor levels showed worse response to anthracycline-based therapy as patients with lower PGRMC1 levels.[ncbi.nlm.nih.gov] […] important apoptosis inhibitor (Bcl-2) and a key protein associated with activation of cell cycle-dependent kinases (cyclin D1).[ncbi.nlm.nih.gov]

  • Adactyly of Foot

    Hereditary and induced modifications of the normal necrotic patterns in the developing limb buds of the rat and mouse: Facts and hypotheses.[docslide.com.br] BCAP31 , ADGRG2 , ATP6AP2 , TENM1 , SSX3 , TIMM17B , SPRY3 , RRAGB , SCML2 , SLC9A6 , ENOX2 , PRDX4 , EBP , STAG2 , RAI2 , PLAC1 , CYSLTR1 , UTP14A , DIAPH2-AS1 , ZNF275 , PGRMC1[ncbi.nlm.nih.gov] 1 protein homolog LMBR1 47 Annotation score: A0A1W2PQV9 A0A1W2PQV9_HUMAN Limb region 1 protein homolog LMBR1 30 Annotation score: Sequence caution i The sequence AAD43188[uniprot.org]

  • Autosomal Recessive Spastic Paraplegia Type 35

    […] dominant) spg3a gene ATL1 AD-FSP ATL-1 FSP1 SPG3 606439 11231 BSCL2, seipin lipid droplet biogenesis associated berardinelli-seip congenital lipodystrophy 2 (seipin) gng3lg, mouse[ukgtn.nhs.uk] More ELISA Kits for FA2H Interaction Partners Human Fatty Acid 2-Hydroxylase (FA2H) interaction partners PGRMC1 may regulate FA2H activity, possibly through its heme chaperone[antibodies-online.com] […] phosphatase 2, regulatory subunit B, beta ( PPP2R2B ); Atassia spinocerebellare, tipo 17 (SCA17) : gene TATA box binding protein ( TBP ); Atassia spinocerebellare, tipo 14[isn.cnr.it]

  • Anauxetic Dysplasia

    Models phenotype-based associations Disease phenotypes are compared with mouse phenotypes, with each mouse model contributing one point to the diagram.[mousephenotype.org] PER3, PEX1, PEX10, PEX11B, PEX12, PEX13, PEX14, PEX16, PEX19, PEX2, PEX26, PEX3, PEX5, PEX6, PEX7, PFAS, PFKM, PFN1, PGAM1, PGAM2, PGAM5, PGBD1, PGC, PGD, PGK1, PGM1, PGR, PGRMC1[inteligene.com.br] POP1 Human Genome Epidemiology (HuGE) Navigator POP1 Atlas of Genetics and Cytogenetics in Oncology and Haematology: POP1 No data available for Genatlas for POP1 Gene RNA-protein[genecards.org]