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76 Possible Causes for PYROGLUTAMATE, SODIUM

  • Metabolic Acidosis

    Following treatment with sodium bicarbonate there was no change in weight, blood pressure, serum creatinine, albumin, sodium, calcium, phosphate, PTH, hemoglobin and CRP.[ncbi.nlm.nih.gov] Abstract High anion gap metabolic acidosis due to pyroglutamic acid (5-oxoproline) is a rare complication of acetaminophen treatment (which depletes glutathione stores) and[ncbi.nlm.nih.gov] The method quantifies glycolic acid, beta-hydroxybutyric acid with good linearity and pyroglutamic acid with a reproducible curvature relation between 1 and 20 mmol/L and[ncbi.nlm.nih.gov]

  • 5-Oxoprolinuria

    Renal tubular acidosis was suspected in the absence of amino aciduria and the patient was treated with sodium bicarbonate.[ncbi.nlm.nih.gov] Abstract Enzyme studies on placenta, cultured skin fibroblasts, and erythrocytes from two sisters with the inborn error 5-oxoprolinuria (pyroglutamic aciduria) indicate that[ncbi.nlm.nih.gov] Nevertheless, vitamin E administration has been continued in addition to the correction of acidosis with sodium bicarbonate.[ncbi.nlm.nih.gov]

  • Pyroglutamate Hydrolase Deficiency

    The metabolism of L -pyroglutamic acid in fibroblasts from a patient with pyroglutamic aciduria: the demonstration of an L -pyroglutamate hydrolase system. Scand. J.[link.springer.com] Bicarbonate (see Sodium Bicarbonate, [[Sodium Bicarbonate]]) References Effect of isotonic volume expansion on extracellular bicarbonate stores in normal dogs.[mdnxs.com] @article{Roesel1981PyroglutamicA, title {Pyroglutamic aciduria (5-Oxoprolinuria) without glutathione synthetase deficiency and with decreased pyroglutamate hydrolase activity[semanticscholar.org]

  • Acidosis

    Sodium acetate may be used specifically to neutralise the acids. At the same time the underlying cause must be treated.[symptoma.com] Long-term use of paracetamol (at therapeutic doses) can cause the accumulation of endogenous organic pyroglutamate, resulting in metabolic acidosis with an elevated anion[ncbi.nlm.nih.gov] Three “newer” anion-gap-generating acids have been recognised recently: D-lactic acid, which can occur in some patients with short bowel syndromes. 5-oxoproline (or pyroglutamic[emergencymedicinecases.com]

  • Phenytoin

    Stevens , The Pyroglutamate Hydantoin Rearrangement , European Journal of Organic Chemistry , 2006 , 11 , (2649-2660) , (2006) .[doi.org] Home Medical Meds and you Medication 27 September 2013 Phenytoin sodium Phenytoin sodium is an anticonvulsant.[health24.com] Active ingredient: 30 mg phenytoin sodium , USP Inactive ingredients: lactose monohydrate, confectioner's sugar, talc, and magnesium stearate.[web.archive.org]

  • Distal Renal Tubular Acidosis

    […] caused by formate Ethylene glycol poisoning caused by glycolate and oxalate Paraldehyde poisoning caused by a variety of organic acids Sulfur poisoning caused by sulphate Pyroglutamic[patient.info] The maximum urinary pCO2 was determined by the oral intake of acetazolamide and sodium bicarbonate.[ncbi.nlm.nih.gov] It involves correction of the acidemia with oral sodium bicarbonate, sodium citrate or potassium citrate.[en.wikipedia.org]

  • Chinese Restaurant Syndrome

    Six subjects, three with a history of flushing, were challenged with 35.7–285.7 mg MSG/kg body weight or 7.1–71.4 mg pyroglutamate/kg body weight.[academic.oup.com] Another concern about MSG is its sodium content.[dailypioneer.com] It Contains Only About One-Third the Sodium of Table Salt Shutterstock MSG is 12 percent sodium, while table salt is 39 percent.[thedailymeal.com]

  • Hawkinsinuria

    An infant in this family presented with metabolic acidosis and excreted quinolacetic acid and pyroglutamic acid in the urine together with the tyrosine derived phenolic acids[ncbi.nlm.nih.gov] Glucose, galactose, fructose, sialic acid, Nitroprusside sodium tests screen for what? Ketones, cystine, homocysteine Azure A tests screen for what?[quizlet.com] Hyperphosphatemia Metabolic Acidosis Hyperkalemia Stage 5: Kidney Failure (GFR Azotemia 52 Acute Interstitial Nephritis Urinalysis Eosinophiluria Proteinuria Fractional Excretion of Sodium[slideplayer.com]

  • Lactic Acidosis

    This is because it can cause an accumulation of pyroglutamic acid in the blood.[healthline.com] Abstract We herein describe a patient with non-occlusive mesenteric ischemia (NOMI) potentially associated with the administration of a sodium glucose co-transporter 2 (SGLT2[ncbi.nlm.nih.gov] Pyroglutamic acidosis ( 8 ) should be considered in any patient presenting with a high anion gap acidosis.[cjasn.asnjournals.org]

  • Autosomal Dominant Distal Renal Tubular Acidosis

    […] rare inborn errors of metabolism including Wilson's disease, mitochondrial myopathies, met achromatic leukodystrophy, pyruvate carboxylase deficiency (Leigh's syndrome) and pyroglutamic[sjkdt.org] It involves correction of the acidemia with oral sodium bicarbonate, sodium citrate or potassium citrate.[flipper.diff.org] […] loss and volume contraction, which causes a compensatory increase in blood levels of aldosterone. [3] Aldosterone causes increased resorption of sodium and loss of potassium[en.wikipedia.org]

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