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14 Possible Causes for Protein, Tunicamycin Responsive

Did you mean: proteus, Tunicamycin Responsive

  • Dengue Virus

    (Tunica), whereas the inhibitor of ER stress response, salubrinal (Sal), decreases calreticulin even in infected cells (Den Sal) and modestly suppresses the response to tunicamycin[] The non-structural protein (NS) 4A is one of the least characterized DV proteins.[] Differential expression analysis identified that 29 proteins were differentially elevated greater than 2-fold in SD groups than DWS- and DWS .[]

  • Autosomal Recessive Juvenile Parkinson Disease

    […] inhibitor MG-132 [30] . 2-Mercaptoethanol ( 2-ME ) and tunicamycin increased the expression of parkin in SH-SY5Y (H) cells, Neuro2a cells, Goto-P3 cells, but not in SH-SY5Y[] Catalogue number PRO-1840 Synonyms Parkin RBR E3 Ubiquitin Protein Ligase, Parkinson Juvenile Disease Protein 2, Parkinson Protein 2 E3 Ubiquitin Protein Ligase (Parkin),[] Substances Calcium-Binding Proteins Luminescent Proteins Membrane Glycoproteins Nerve Tissue Proteins SYT11 protein, human Ubiquitin Synaptotagmins Green Fluorescent Proteins[]

  • Severe Acute Respiratory Syndrome

    Administration of E protein in trans reduced the stress response in cells infected with rSARS-CoV-ΔE or with respiratory syncytial virus, or treated with drugs, such as tunicamycin[] All constructs were expressed as recombinant proteins in yeast.[] The genome encodes for proteins that are homologous to known coronavirus proteins, such as the replicase proteins (ORFs 1a and 1b) and the four major structural proteins:[]

  • Wolfram Syndrome

    Treatment of fibroblasts and MIN6 cells with thapsigargin or tunicamycin increased WFS1 mRNA [18] .[] Miner1 is the first functionally different protein that shares the NEET fold with its recently identified paralog mitoNEET, an outer mitochondrial membrane protein.[] Here, we identify the endoplasmic reticulum (ER)-localized Wolfram syndrome protein (WFS1) as a specific degradation substrate of Smurf1.[]

  • Japanese Encephalitis

    In this respect, it is notable that PKR is activated in mammalian cells in response to treatment with tunicamycin or thagasgagine, which causes ER stress by inhibiting protein[] Such malfunctioning can result from a variety of ER stresses, including the inhibition of protein glycosylation and calcium imbalance.[] We further found that the JEV envelope protein E, but not other viral components, significantly downregulates BST2 with the viral protein M playing an auxiliary role in the[]

  • Amyotrophic Lateral Sclerosis

    […] pharmacology Unfolded Protein Response/physiology Substances SOD1 protein, human Tunicamycin Tryptophan Superoxide Dismutase-1 Grant support R01 NS067206/NS/NINDS NIH HHS[] We will also discuss an intriguingly central role of the protein TDP-43 in the majority of cases of this devastating disease.[] PubMed CrossRef Google Scholar Hesketh S, Thompsett AR, Brown DR (2012) Prion protein polymerisation triggered by manganese-generated prion protein seeds.[]

  • Stress

    […] pharmacology Unfolded Protein Response/physiology Substances SOD1 protein, human Tunicamycin Tryptophan Superoxide Dismutase-1 Grant support R01 NS067206/NS/NINDS NIH HHS[] Abstract It is well established today that heterologous overexpression of proteins is connected with different stress reactions.[] Yes-associated protein (YAP) is a powerful regulator and is overexpressed in many cancers, including HCC.[]

  • Placental Insufficiency

    Han , Reducing Agent and Tunicamycin-responsive Protein (RTP) mRNA Expression in the Placentae of Normal and Pre-eclamptic Women , Placenta , 25 , 1 , (62) , (2004) .[] On the other hand, oxidative destruction of proteins increased in placental insufficiency irrespective of pregnancy outcome.[] Epithelial membrane protein-2 (EMP2) is a tetraspan protein predicted to regulate placental development.[]

  • Aplastic Anemia

    Using archived bone marrow aspirate samples, we demonstrate that the culture-expanded AAA myeloid cells have an increased response to ER stress induced by tunicamycin leading[] Peripheral blood samples were analyzed by flow cytometry for the presence of glycophosphatidyl inositol (GPI)–anchored protein-deficient granulocytes at presentation and at[] […] managed in ways appropriate to their pathophysiology, which is more accurately determined by using markers such as the presence of glycosylphosphatidylinositol-anchored protein-deficient[]

  • Perilla

    The ER stressor tunicamycin was employed as a positive control.[] Abstract Protein tyrosine phosphatases (PTPs) are enzymes that catalyze protein tyrosine dephosphorylation of which Src homology phosphatase-1 (SHP-1) is one of the best-validated[] A transactivation domain of MYC-RP/GP and Delila could be located in the region between the 193rd and the 420th amino acid of MYC-RP/GP proteins.[]

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