Create issue ticket

764 Possible Causes for Proteins, Rapamycin Binding

Did you mean: Proteins, Rapamycin, Binding

  • Sirolimus

    , apoptosis proteins, and epithelial-mesenchymal-transition (EMT) proteins.[ncbi.nlm.nih.gov] - binding protein 12 (FKBP12) to form a complex which inhibits the mammalian target of rapamycin (mTOR) pathway by directly binding to mTOR Complex 1 (mTORC1).[caymanchem.com] protein kinase mTOR.[dx.doi.org]

  • Meningitis

    CSF protein and glucose measurements are therefore essential in management but may be neglected in clinical practice.[ncbi.nlm.nih.gov] Voriconazole interferes with the metabolism of several other drugs, including cyclosporine, tacrolimus, sirolimus, and warfarin, potentially leading to toxic levels of these[dx.doi.org] […] after infection Ferric binding protein (FbpA) Iron binding Lactoferrin binding protein (LbpA) Lactoferrin binding Neiserrial surface protein A (NspA) Immunogenic surface[doi.org]

  • Lymphangioleiomyomatosis

    Mutations in TSC1 or TSC2 lead to the activation of the mammalian target of rapamycin complex-1, a kinase that regulates growth factor-dependent protein translation, cell[ncbi.nlm.nih.gov] After discontinuation of sirolimus, the decline in lung function resumed in the sirolimus group and paralleled that in the placebo group.[ncbi.nlm.nih.gov] We report here that estrogen increased LAM patient-derived cells' resistance to anoikis in vitro, accompanied by decreased accumulation of the proapoptotic protein Bim, an[ncbi.nlm.nih.gov]

  • Immunosuppressive Drug

    We identified several proteins and pathways as being involved in the mechanism of action of FTY720.[ncbi.nlm.nih.gov] Regimens could be simplified using drugs with long half-lives requiring once-daily administration, such as sirolimus.[ncbi.nlm.nih.gov] Clin Chem 42 : 1417 -1425, 1996 Chen J, Zheng XF, Brown EJ, Schreiber SL: Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated[jasn.asnjournals.org]

  • Protein Losing Enteropathy

    Differential diagnoses for low protein levels are reduced intake or malnutrition, decreased protein synthesis due to hepatic dysfunctions, and protein losing nephropathy.[symptoma.com] At the time of writing this report, the beneficial effect of sirolimus has lasted for more than 3 years.[ncbi.nlm.nih.gov] She also had severe protein C and protein S depletion from GI loss which caused extensive thrombosis.[ncbi.nlm.nih.gov]

  • Proteinuria

    Healthy kidneys do not allow a significant amount of protein to pass through their filters.[webmd.com] CASE REPORT: A 43-year-old man who received a cadaveric kidney was converted to sirolimus from cyclosporine after being diagnosed with adenocarcinoma and carcinoma clarocellulare[ncbi.nlm.nih.gov] […] significant complication after liver transplantation (LT), but the role of pre-existing renal insufficiency and proteinuria remains unclear among LT recipients receiving sirolimus[ncbi.nlm.nih.gov]

  • Low Protein Diet

    BACKGROUND & AIMS: Amino acid (AA) availability is critical to maintain protein homeostasis and reduced protein intake causes a decline in protein synthesis.[ncbi.nlm.nih.gov] Z Nudelman, M Friedman, D Barasch, A Nemirovski, M Findler, A Pikovsky, JS Gutkind and R Czerninski , Levels of sirolimus in saliva and blood following mouthwash application[doi.org] […] involved in intracellular signalling distal to IGF1R, which include members of the insulin-receptor substrate ( IRS ) family, AKT , target of rapamycin ( TOR ) and S6 kinase[doi.org]

  • Wiskott Aldrich Syndrome

    Abstract Wiskott–Aldrich syndrome protein family verprolin-homologous protein 2 (WAVE2) is a protein that mediates actin cytoskeletal reorganization and lamellipodia protrusion[ncbi.nlm.nih.gov] ) in Kidney Transplant Recipients Completed NCT00121810 Phase 4 mycophenolate mofetil [CellCept];Corticosteroids;Calcineurin inhibitors;Sirolimus 8 Drug-Drug Interaction of[malacards.org] Several actin regulatory proteins were implicated in regulating the actin machinery, such as members of the Wiskott-Aldrich syndrome protein (WASp) family.[ncbi.nlm.nih.gov]

  • Diamond-Blackfan Anemia

    , along with rarer abnormalities of additional ribosomal proteins.[ncbi.nlm.nih.gov] 148-82-3 4053 460612 39 Mycophenolic acid Approved Phase 2,Phase 1,Not Applicable 24280-93-1 446541 40 Prednisone Approved, Vet_approved Phase 1, Phase 2 53-03-2 5865 41 Sirolimus[malacards.org] Mutations in the ribosomal protein (RP) S19 are found in 25% of patients, while mutations in other proteins of the small ribosomal subunit--RPS17 and RPS24--have been found[ncbi.nlm.nih.gov]

  • Soy Allergy

    […] food proteins.[jn.nutrition.org] Cyclosporin A, FK506 (tacrolimus), and rapamycin (sirolimus) are powerful immunosuppressive agents that interfere with T-cell signaling 14-4.[ncbi.nlm.nih.gov] Generally, these studies show lower allergic reactivity for soy proteins vs. other food allergens.[ncbi.nlm.nih.gov]

Further symptoms