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156 Possible Causes for Ser Ile Lys Pro Ser Ala Tyr Leu Pro Leu Arg Phe NH2

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  • Mechlorethamine

    Abstract Two groups of 20 patients with psoriasis were treated with mechlorethamine applied topically (group A) or with PUVA combined with mechlorethamine (group B).[ncbi.nlm.nih.gov] Thus, 38% of the patients in both groups became contact sensitized to mechlorethamine.[ncbi.nlm.nih.gov] The addition of UV-B to topical applications of mechlorethamine reduced the incidence of allergic contact dermatitis to mechlorethamine from 64% to 22%.[ncbi.nlm.nih.gov]

  • Childhood Hodgkin's Disease

    Forty-six received mechlorethamine (Mustargen; Merk Sharpe & Dohme, West Point, PA), vincristine (Oncovin; Eli Lilly and Company, Indianapolis), procarbazine, and prednisolone[ncbi.nlm.nih.gov] There are several effective regimens, using agents such as vincristine, procarbazine, doxorubicin, prednisone, etoposide, cyclophosphamide, vinblastine, bleomycin, mechlorethamine[symptoma.com]

  • Alkylating Agent

    The mechanistic study proves that the DNA cross-linking activity is mainly due to the release of DNA alkylating mechlorethamine.[pubs.rsc.org] Abstract Exposure of epithelial respiratory cells to the alkylating agent, mechlorethamine (HN2), induces anoikis initiated by mitochondrial depolarization and caspase-2 activation[ncbi.nlm.nih.gov] HPLC-ESI -MS/MS analysis of total proteolytic digests of DPCs revealed the chemical structures of the cross-links produced by DEB and mechlorethamine to be 1-(S-cysteinyl)[conservancy.umn.edu]

  • Cutaneous T-Cell Lymphoma

    These stages can be effectively controlled by skin-directed therapies such as mechlorethamine gel (Valchlor ).[ncbi.nlm.nih.gov] KEYWORDS: CTCL; Valchlor ; cutaneous T-cell lymphoma; mechlorethamine gel; mycosis fungoides; nitrogen mustard Conflict of interest statement Disclosure Dr McGirt is a consultant[ncbi.nlm.nih.gov] […] therapies are useful for patch and limited plaque disease and include topical treatments such as corticosteroids, retinoids, or imiquimod (which activates immune cells), mechlorethamine[uacc.arizona.edu]

  • Procarbazine

    PCB was one of the four drugs combined in mechlorethamine, vincristine, PCB, prednisolone (MOPP), one of the first combination chemotherapy regimens to show that advanced-stage[ncbi.nlm.nih.gov] Abstract The authors report the clinical features of hypersensitivity reactions believed to result from procarbazine in eight patients treated with mechlorethamine, vincristine[ncbi.nlm.nih.gov] […] procarbazine [ pro-kahr bah-zēn ] an antineoplastic agent used primarily in combination with mechlorethamine , vincristine , and prednisone in the regimen called MOPP for[medical-dictionary.thefreedictionary.com]

  • T-Cell Lymphoma

    KEYWORDS: CTCL; Valchlor ; cutaneous T-cell lymphoma; mechlorethamine gel; mycosis fungoides; nitrogen mustard Conflict of interest statement Disclosure Dr McGirt is a consultant[ncbi.nlm.nih.gov] […] therapies are useful for patch and limited plaque disease and include topical treatments such as corticosteroids, retinoids, or imiquimod (which activates immune cells), mechlorethamine[uacc.arizona.edu] Topical chemotherapy in cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine[rarediseases.org]

  • Antineoplastic Agent

    The alkylation sequence for mechlorethamine reacting with the N-7 position of deoxyguanylate is shown in Figure 54-4 .[clinicalgate.com] Megestrol Megace (R) L-Pam, M, MEL Melphalan - L-phenylalanine mustard, L-sarcolysin Alkeran (R) IV-M, IV-MEL Melphalan hydrochloride IV Alkeran (R) MESNA MESNA Mesnex (R) HN(2) Mechlorethamine[meds.com] Among these are busulfan , cyclophosphamide , ifosfamide , and thiotepa ; the nitrogen mustards chlorambucil , mechlorethamine , and melphalan ; and the nitrosoureas carmustine[medical-dictionary.thefreedictionary.com]

  • Mycosis Fungoides

    These stages can be effectively controlled by skin-directed therapies such as mechlorethamine gel (Valchlor ).[ncbi.nlm.nih.gov] (MCH) 0.04% Formulation in Mycosis Fungoides Completed NCT00535470 Phase 2 0.04% Mechlorethamine gel Search NIH Clinical Center for Mycosis Fungoides Inferred drug relations[malacards.org] Topical chemotherapy in cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine[rarediseases.org]

  • Uracil Mustard

    Total doses of uracil mustard were similar to those of mechlorethamine, although there were variations in the dose schedule.[ncbi.nlm.nih.gov] Mechlorethamine is just an "… As many estimable colleagues have noted, guanine's weird.[scienceblogs.com] First, if a cyclic phosphamide group replaced the N-methyl of mechlorethamine, the compound might be relatively inert, presumably because the bis-(2-chloroethyl) group of[chem.libretexts.org]

  • Mycosis

    Topical chemotherapy in cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine[rarediseases.org] Mechlorethamine (nitrogen mustard) is a drug that can be painted onto the skin to suppress the cancer.[encyclopedia.com] Its effectiveness is similar to mechlorethamine. In addition to side effects in the skin, this drug may cause myelosuppression .[encyclopedia.com]

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