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8,670 Possible Causes for T cell, during, gamma delta, immune, Proliferation, response

  • Influenza

    Immune thrombocytopenia (ITP) is an isolated autoimmune condition, often preceded by a viral infection.[ncbi.nlm.nih.gov] CD4 T cells in vitro.[dx.doi.org] […] and humoral immune responses to develop.[doi.org] We reported influenza-associated encephalitis/encephalopathy in children during 2014-2017 in Taiwan, focusing on neurological presentations, neuroimaging correlations, and[ncbi.nlm.nih.gov] Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices [ACIP]. MMWR 2004;53[No. RR-6]:1-40).[ncbi.nlm.nih.gov] […] the median weekly death rate for a given city during the study period; and ( iii ) cumulative excess deaths during the study period.[dx.doi.org]

  • X-Linked Severe Combined Immunodeficiency

    Abstract Retroviral gene therapy can restore immunity to infants with X-linked severe combined immunodeficiency (XSCID) caused by mutations in the IL2RG gene encoding the[ncbi.nlm.nih.gov] He had very few alpha beta T cells but had a considerable number of gamma delta T cells in his peripheral blood.[ncbi.nlm.nih.gov] The humoral innate immune response consists of multiple components, including the naturally occurring antibodies (NAb), pentraxins and the complement and contact cascades.[hdl.handle.net] Identification and characterization of LMO4 , an LMO gene with a novel pattern of expression during embryogenesis. Proc. Natl. Acad. Sci. USA 95 : 11257 -11262. 16.[doi.org] LMO2 -Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1 By , C. Von Kalle , M. Schmidt , M. P. McCormack , N. Wulffraat , P.[sciencemag.org] Diversity of the TCRVβ repertoire was comparable to normal and, furthermore, mitogen-induced proliferation of the patient's T cells was minimally impaired compared to healthy[ncbi.nlm.nih.gov]

  • Interleukin-2

    A delayed or inadequate immune response can lead to prolonged disease, while an excessive or under-regulated response can lead to autoimmunity.[ncbi.nlm.nih.gov] […] that the enhanced production of kynurenine, a metabolite related to tryptophan catabolism, also impairs memory CD4 T-cell survival and interferes with IL-2 signaling early during[ncbi.nlm.nih.gov] […] of Y392 and Y510 inhibited proliferation only partially.[doi.org] It is expressed by CD4 and CD8 T cells, gamma delta T cells, B cells, dendritic cells, and eosinophils.[novusbio.com] IL-10 by itself could not promote the proliferation of CD8 T cells but could significantly enhance IL-2-mediated promotion of CD8 T cell proliferation.[ncbi.nlm.nih.gov] T memory stem cells (T SCM , CD95 CD45RO - CD45RA CD27 ) were present variably during T-cell expansion.[ncbi.nlm.nih.gov]

  • Cutaneous T-Cell Lymphoma

    immune response.[ncbi.nlm.nih.gov] Unlike most non-Hodgkin lymphomas (which are generally B cell related), CTCL is caused by a mutation of T cells.[en.wikipedia.org] […] to prolong response.[ncbi.nlm.nih.gov] OBJECTIVES: To extend our previous analysis on CTCL incidence across Canada and to provide all the collected data on CTCL patient incidence in Canada during the period of[ncbi.nlm.nih.gov] Our results indicate that exogenous SAMHD1 expression inhibits HuT78 cell growth and proliferation in part by increasing apoptosis.[ncbi.nlm.nih.gov] Abstract Primary cutaneous T-cell lymphoma gamma-delta subtype is an extremely rare entity of all the cutaneous T-cell lymphomas.[ncbi.nlm.nih.gov]

  • T-Cell Lymphoma

    J Acquired Immune Defic Syndr . 2000;26:371–376. 21. Harris NL, Jaffe ES, Diebold J, et al.[journals.lww.com] Conclusions: PTCL, NOS constituted about 30.68% of all PTCLs in our institution during a 5-year period and was the second most common type of PTCL.[ncbi.nlm.nih.gov] We determined the effects of PAK1 knockdown on cell proliferation and apoptosis in CTCL cells by MTS assay and flow cytometry.[ncbi.nlm.nih.gov] CONCLUSIONS: We believe this is a case of not otherwise specified gamma-delta T-cell lymphoma.[ncbi.nlm.nih.gov] T-cell acute lymphoblastic leukemia and lymphoma is caused by transformation of precursor T cells.[symptoma.com] In addition, we found that RSV suppressed the phosphorylation level of AKT and Stat3, and activated DNA damage response (DDR) pathway directly or through up-regulation of[ncbi.nlm.nih.gov]

  • Inflammation

    HIV-infection is associated with ongoing activation of the immune system and persistent inflammation.[ncbi.nlm.nih.gov] […] is active during wasting conditions ( 53 ).[doi.org] The effect of rLRRFIP-1 on cellular proliferation, inflammation, and collagen deposition was also investigated.[ncbi.nlm.nih.gov] {gamma}{delta} T cell-induced hyaluronan production by epithelial cells regulates inflammation . J. Exp. Med. 201 , 1269–1279 (2005). 7. Adamson, I.Y. & Bowden, D.H.[doi.org] T Cells and Inflammation Lymphocytes from the so-called T helper cell (Th) lineage (characterised by the expression of the surface molecule CD4) play a central role in the[sterna-biologicals.com] […] lymphocytes (CD8 ); T lymphocytes displaying major histocompatibility complex class II antigen (DR ), vascular adhesion molecule 4 (VLA-4) (CD49d ), Fas antigen (CD95 ), or gamma-delta[doi.org]

  • Hepatosplenic T-cell Lymphoma

    We reviewed the literature and identified 60 patients with immune disorders who subsequently developed HSTCL.[ncbi.nlm.nih.gov] during terminal phase, indicating that this change represented a blast-like transformation of the patient's original lymphoproliferative disorder.[ncbi.nlm.nih.gov] Hepatosplenic T-Cell lymphoma (HSTCL) which is a rare aggressive form of Peripheral T-Cell lymphoma that is characterized by primary extranodal disease with malignant T-cell proliferation[ncbi.nlm.nih.gov] We conclude that hepatosplenic gamma delta T-cell lymphoma is a distinct clinicopathologic entity derived from cytotoxic gamma delta T cells, and should be distinguished from[ncbi.nlm.nih.gov] The cell of origin for this disease is an immature cytotoxic T-cell clonally expressing the γδ T-cell receptor.[en.wikipedia.org] CONCLUSIONS: Hepatosplenic T-cell lymphoma is a distinct T cell lymphoma associated with an aggressive clinical course, a poor response to conventional treatment, and an exceedingly[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    KEYWORDS: acute infection; anti-viral immunity; cytokines; dendritic cells; herpesvirus; immune dysregulation; immune regulation; virus[ncbi.nlm.nih.gov] The Epstein-Barr virus (EBV) had infected both CD19- and CD8-positive cells, and clonal proliferation of EBV-infected cells and T-cells was detected.[ncbi.nlm.nih.gov] The aim of the study was to analyze frequencies of CD28 CD95 , CD28 CD95 , CD28 CD95 T cell subsets putative naïve (T(N)), central (T(CM)) and effector memory (T(EM)) T cells[ncbi.nlm.nih.gov] responses.[dx.doi.org] Abstract Here we present evidence for previously unappreciated B-cell immune dysregulation during acute Epstein-Barr virus (EBV)-associated infectious mononucleosis (IM).[ncbi.nlm.nih.gov] Development of AIM is accompanied by a change in the ratio of immune cells.[ncbi.nlm.nih.gov]

    Missing: gamma delta
  • Lymphoproliferative Disorder

    It is generally accepted that impaired immune function due to immunosuppression is a primary cause of EBV PTLD.[ncbi.nlm.nih.gov] Methods: Among 33 patients developing LPD during MTX treatment, 20 LPDs regressed spontaneously within 12 weeks after MTX cessation (regressive LPD), and 13 did not regress[ncbi.nlm.nih.gov] , and histiocytic/dendritic cell proliferations.[ncbi.nlm.nih.gov] […] panniculitis like T-NHL § Primary cutaneous gamma delta T cell lymphoma § Primary cutaneous epidermotropic CD8 cytotoxic T cell lymphoma § Primary cutaneous epidermotropic[ihaematology.com] In this case, the proliferated T-cell in the paracortex of lymph node showed T-cell receptor gene rearrangement, which indicated a clonal proliferation.[ncbi.nlm.nih.gov] Results One hundred eleven of 126 patients had a complete or partial response (88%; 95% CI, 81% to 93%), of whom 88 had a complete response (70%; 95% CI, 61% to 77%).[ncbi.nlm.nih.gov]

  • T-cell Acute Lymphoblastic Leukemia

    Nevertheless, the effects of PI3K/Akt/mTOR inhibitors on T lymphocytes, a key component of immune responses, have been seldom explored.[ncbi.nlm.nih.gov] T-ALL stems from hematopoietic progenitor cells that are set for T-cell development and it is thought that partially developed thymocytes are, in fact, the source of this[symptoma.com] KEYWORDS: CDKN1B deletion; MEF2C dysregulation; T-cell acute lymphoblastic leukemia; glucocorticoid response; immunophenotype[ncbi.nlm.nih.gov] […] connective tissue diseases are most encountered, etiological factors, pericardial effusions, can also rarely emerge because of malign disease in childhood and it often develops during[ncbi.nlm.nih.gov] These data indicate that Lhx2 is capable of blocking proliferation of T-ALL-derived cells by both LMO2-dependent and -independent means.[ncbi.nlm.nih.gov] […] genetics Receptors, Antigen, T-Cell, gamma-delta/immunology* Receptors, Antigen, T-Cell, gamma-delta/metabolism Survival Analysis T-Lymphocytes/immunology* T-Lymphocytes[ncbi.nlm.nih.gov]