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Sexual Dysfunction
This study is aimed to analyze the relationship between sexual function and topiramate to avoid topiramate-associated SD.[ncbi.nlm.nih.gov]
Sexual adversity usually occurred from 4weeks after topiramate use but favorably subsided without eventful complications after topiramate substitution or dose reduction in[ncbi.nlm.nih.gov]
The daily dose of topiramate in patients with SD was within the recommended dose.[ncbi.nlm.nih.gov]
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Priapism
KEYWORDS: Alcohol dependence; Dose-dependent; Priapism; Topiramate[ncbi.nlm.nih.gov]
This paper presents a case of priapism associated with topiramate use.[ncbi.nlm.nih.gov]
RESULTS: Reversible priapism (stuttering subtype) is associated with topiramate.[ncbi.nlm.nih.gov]
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Liver Injury
Topiramate commonly causes neurological adverse effects such as psychomotor slowing and somnolence.[ncbi.nlm.nih.gov]
Although it is common in first-generation antiepileptic drugs (AEDs), it is rare in newer AEDs such as topiramate.[ncbi.nlm.nih.gov]
Hepatotoxicity by topiramate is rare and has been previously reported in combination with other drugs such as valproate and carbamazepine.[ncbi.nlm.nih.gov]
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Adrenal Insufficiency
[…] as drugs which increase hepatic glucocorticoid metabolism by CYP3A4 induction (for example; rifampicin, mitotane, phenytoin, oxcarbazepine, carbamazepine, phenobarbitone, topiramate[clinicaladvisor.com]
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Fluoxetine
RESULTS: Patients treated with fluoxetine plus topiramate lost more weight at 3 and 6 months before surgery.[ncbi.nlm.nih.gov]
Among drugs that have been evaluated for weight loss include antidepressants (fluoxetine) and antiepileptic (topiramate).[ncbi.nlm.nih.gov]
200 mg/day (Group B); and the third group of patients were treated with fluoxetine 40 mg and 200 mg of topiramate/day (Group C).[ncbi.nlm.nih.gov]
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Ecstasy
The case of an ecstasy consumer, who started to discontinue ecstasy under topiramate treatment is presented here.[ncbi.nlm.nih.gov]
Antiepileptics/mood stabilizers with glutamate inhibition activity like topiramate may present a promising new approach for challenging the consequence of drug abuse.[ncbi.nlm.nih.gov]
Topiramate is an antiepileptic drug that has a broad spectrum of antiseizure effects, which appear to be the result of several neurostabilizing pharmacological mechanisms[ncbi.nlm.nih.gov]
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Anterior Uveitis
PURPOSE: To report a rare case of bilateral anterior uveitis with hypopyon formation following systemic topiramate use.[ncbi.nlm.nih.gov]
Abstract Topiramate is a recognized cause of drug-induced acute angle-closure glaucoma.[ncbi.nlm.nih.gov]
CONCLUSION: Topiramate should be added to the list of drugs that may cause anterior uveitis and hypopyon formation.[ncbi.nlm.nih.gov]
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Myopia
We described a very rare case of topiramate induced acute onset myopia during use for migraine.[ncbi.nlm.nih.gov]
Treatment consists of replacing topiramate with appropriate medication, strong cycloplegia, and topical steroids.[ncbi.nlm.nih.gov]
This article describes a case of topiramate-induced acute transient myopia. The underlying mechanism and management is discussed.[ncbi.nlm.nih.gov]
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Postherpetic Neuralgia
[…] the use of topiramate specifically for treatment of PHN.[ncbi.nlm.nih.gov]
Topiramate was initiated after the patient failed treatment with 4 other antiepileptic medications due to various adverse events.[ncbi.nlm.nih.gov]
Further studies are needed to determine whether topiramate should receive a stronger recommendation for the treatment of PHN.[ncbi.nlm.nih.gov]
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Hyperventilation
Withdrawing topiramate reduced both CSF acidosis and hyperventilation. The mechanism of topiramate-induced CSF acidosis remains unclear.[ncbi.nlm.nih.gov]
The problem resolved within 24 hours after discontinuing topiramate.[ncbi.nlm.nih.gov]
The acid-base status of critically ill patients receiving topiramate should be monitored carefully.[ncbi.nlm.nih.gov]